1
HESI PN Pharmacology Retake Questions with Answers
(100% Correct Answers)
Cephalexin monohydrate (Keflex) —ANS: An antibiotic prescribed for clients with
postoperative infections, requiring assessment for penicillin allergy due to cross-allergy
risks.
Cytosine arabinoside (Arc-C) —ANS: An antimetabolite used in chemotherapy that
can cause stomatitis and mucosal ulcerations as signs of toxicity.
Acetaminophen (Tylenol) overdose assessment —ANS: Most important to assess for
pain in the flank area.
Naproxen dosing frequency —ANS: Typically prescribed every 8 hours, with a peak
effect occurring in one to two hours.
Oral metronidazole (Flagyl) instructions —ANS: The nurse should instruct the client
to increase fluid intake, avoid drinking alcohol, use condoms until treatment is
completed, and ensure all sexual partners are treated.
© 2025 All rights reserved
, 2
Cross-allergy —ANS: A phenomenon where an allergy to one drug (e.g., penicillins)
may indicate an allergy to another related drug (e.g., cephalosporins).
Antimetabolite toxicity signs —ANS: Key signs include stomatitis and mucosal
ulcerations.
Nonsteroidal anti-inflammatory drugs (NSAIDs) response —ANS: Individual
responses to NSAIDs are variable, and alternative medications may be indicated if
effectiveness is not achieved.
Hydration before chemotherapy —ANS: It is important to hydrate the client with IV
fluids before and after the infusion of cytosine arabinoside.
Pain assessment in acetaminophen overdose —ANS: Pain assessment should focus on
the flank area in cases of acetaminophen overdose.
Therapeutic blood levels —ANS: Therapeutic blood levels of certain drugs may take 4
to 6 weeks to be reached.
Corticosteroids for osteoarthritis —ANS: Corticosteroids are not indicated for the
treatment of osteoarthritis.
© 2025 All rights reserved
HESI PN Pharmacology Retake Questions with Answers
(100% Correct Answers)
Cephalexin monohydrate (Keflex) —ANS: An antibiotic prescribed for clients with
postoperative infections, requiring assessment for penicillin allergy due to cross-allergy
risks.
Cytosine arabinoside (Arc-C) —ANS: An antimetabolite used in chemotherapy that
can cause stomatitis and mucosal ulcerations as signs of toxicity.
Acetaminophen (Tylenol) overdose assessment —ANS: Most important to assess for
pain in the flank area.
Naproxen dosing frequency —ANS: Typically prescribed every 8 hours, with a peak
effect occurring in one to two hours.
Oral metronidazole (Flagyl) instructions —ANS: The nurse should instruct the client
to increase fluid intake, avoid drinking alcohol, use condoms until treatment is
completed, and ensure all sexual partners are treated.
© 2025 All rights reserved
, 2
Cross-allergy —ANS: A phenomenon where an allergy to one drug (e.g., penicillins)
may indicate an allergy to another related drug (e.g., cephalosporins).
Antimetabolite toxicity signs —ANS: Key signs include stomatitis and mucosal
ulcerations.
Nonsteroidal anti-inflammatory drugs (NSAIDs) response —ANS: Individual
responses to NSAIDs are variable, and alternative medications may be indicated if
effectiveness is not achieved.
Hydration before chemotherapy —ANS: It is important to hydrate the client with IV
fluids before and after the infusion of cytosine arabinoside.
Pain assessment in acetaminophen overdose —ANS: Pain assessment should focus on
the flank area in cases of acetaminophen overdose.
Therapeutic blood levels —ANS: Therapeutic blood levels of certain drugs may take 4
to 6 weeks to be reached.
Corticosteroids for osteoarthritis —ANS: Corticosteroids are not indicated for the
treatment of osteoarthritis.
© 2025 All rights reserved
