TEST BANK
RUBIN'S PATHOLOGY: CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION
DAVID S. STRAYER, EMANUEL RUBIN
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
Table of Contents:
Chapter 1: Cell Adaptation, Injury and Death
Chapter 2: Inflammation
Chapter 3: Repair, Regeneration and Fibrosis
Chapter 4: Immunopathology
Chapter 5: Neoplasia
Chapter 6: Developmental and Genetic Diseases
Chapter 7: Hemodynamic Disorders
Chapter 8: Environmental and Nutritional Pathology
Chapter 9: Infectious and Parasitic Diseases
Section II: Pathogenesis of Systemic Conditions Expandable section
Chapter 10: Aging
Chapter 11: Systemic Autoimmune Diseases
Chapter 12: Sepsis
Chapter 13: Obesity and Diabetes Mellitus
Chapter 14: The Pathology of Pregnancy
Chapter 15: The Amyloidoses
Section III: Diseases of Individual Organ SystemsExpandable section
Chapter 16: Blood Vessels
Chapter 17: The Heart
Chapter 18: The Respiratory System
Chapter 19: The Gastrointestinal Tract
Chapter 20: The Liver and Biliary System
Chapter 21: The Pancreas
Chapter 22: The Kidney
Chapter 23: The Lower Urinary Tract and Male Reproductive System
Chapter 24: The Female Reproductive System and Peritoneum
Chapter 25: The Breast
Chapter 26: Hematopathology
Chapter 27: The Endocrine System
Chapter 28: The Skin
Chapter 29: The Head and Neck
Chapter 30: Bones, Joints and Soft Tissue
Chapter 31: Skeletal Muscle and Peripheral Nervous System
Chapter 32: The Central Nervous System
Chapter 33: The Eye
Chapter 34: Forensic Pathology
,Rubin's Pathology: Clinicopathologic Foundations of
MedicineChapter 1: Cell Adaptation, Injury and Death
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
1. of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
2. Adaptation to the reduced size of the liver leads to _ of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
A person eating peanuts starts choking and collapses. His airway obstruction is partially
cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
3. caused a cerebral infarction and resulting _ in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
Bacteria and viruses cause cell damage by , which is unique from the intracellular
4. damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
D) decreasing protein synthesis and function
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
A) destroying phospholipids in the cell membrane.
B) altering the immune response of the cell.
C) disrupting calcium storage in the cell.
D) inactivation of enzymes and mitochondria.
, 6. Injured acells ahave aimpaired aflow aof asubstances athrough athe acell amembrane aas aa aresult aof:
A) increased afat aload.
B) altered apermeability.
C) altered aglucose autilization.
D) increased asurface areceptors.
7. Reversible aadaptive aintracellular aresponses aare ainitiated aby:
A) stimulus aoverload.
B) genetic amutations.
C) chemical amessengers.
D) mitochondrial aDNA.
8. Injured acells abecome avery aswollen aas aa aresult aof:
A) increased acell aprotein asynthesis.
B) altered acell avolume aregulation.
C) passive aentry aof apotassium ainto athe acell.
D) bleb aformation ain athe aplasma amembrane.
A adiabetic apatient ahas aimpaired asensation, acirculation, aand aoxygenation aof ahis afeet. aHe
asteps aon aa apiece aof aglass, athe awound adoes anot aheal, aand athe aarea atissue abecomes
anecrotic. aThe anecrotic
9. cell adeath ais a characterized aby:
A) rapid aapoptosis.
B) cellular arupture.
C) shrinkage aand acollapse.
D) chronic ainflammation.
A a99-year-old awoman ahas aexperienced athe adecline aof acell afunction aassociated awith aage. aA
10. group aof atheories a of acellular aaging afocus aon aprogrammed:
A) changes awith agenetic ainfluences.
B) elimination aof acell areceptor asites.
C) insufficient atelomerase aenzyme.
D) DNA amutation aor afaulty arepair.
An a89-year-old afemale apatient ahas aexperienced asignificant adecreases ain aher amobility
aand astamina aduring aa a3-week ahospital astay afor athe atreatment aof aa afemoral ahead afracture.
aWhich aof athe afollowing aphenomena amost alikely aaccounts afor athe apatients adecrease ain
amuscle afunction
11. that aunderlies aher areduced amobility?
A) Impaired amuscle acell ametabolism aresulting afrom ametaplasia
B) Dysplasia aas aa aconsequence aof ainflammation aduring abone aremodeling
C) Disuse aatrophy aof amuscle a cells aduring aa aprolonged aperiod aof aimmobility
RUBIN'S PATHOLOGY: CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION
DAVID S. STRAYER, EMANUEL RUBIN
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
Table of Contents:
Chapter 1: Cell Adaptation, Injury and Death
Chapter 2: Inflammation
Chapter 3: Repair, Regeneration and Fibrosis
Chapter 4: Immunopathology
Chapter 5: Neoplasia
Chapter 6: Developmental and Genetic Diseases
Chapter 7: Hemodynamic Disorders
Chapter 8: Environmental and Nutritional Pathology
Chapter 9: Infectious and Parasitic Diseases
Section II: Pathogenesis of Systemic Conditions Expandable section
Chapter 10: Aging
Chapter 11: Systemic Autoimmune Diseases
Chapter 12: Sepsis
Chapter 13: Obesity and Diabetes Mellitus
Chapter 14: The Pathology of Pregnancy
Chapter 15: The Amyloidoses
Section III: Diseases of Individual Organ SystemsExpandable section
Chapter 16: Blood Vessels
Chapter 17: The Heart
Chapter 18: The Respiratory System
Chapter 19: The Gastrointestinal Tract
Chapter 20: The Liver and Biliary System
Chapter 21: The Pancreas
Chapter 22: The Kidney
Chapter 23: The Lower Urinary Tract and Male Reproductive System
Chapter 24: The Female Reproductive System and Peritoneum
Chapter 25: The Breast
Chapter 26: Hematopathology
Chapter 27: The Endocrine System
Chapter 28: The Skin
Chapter 29: The Head and Neck
Chapter 30: Bones, Joints and Soft Tissue
Chapter 31: Skeletal Muscle and Peripheral Nervous System
Chapter 32: The Central Nervous System
Chapter 33: The Eye
Chapter 34: Forensic Pathology
,Rubin's Pathology: Clinicopathologic Foundations of
MedicineChapter 1: Cell Adaptation, Injury and Death
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
1. of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
2. Adaptation to the reduced size of the liver leads to _ of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
A person eating peanuts starts choking and collapses. His airway obstruction is partially
cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
3. caused a cerebral infarction and resulting _ in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
Bacteria and viruses cause cell damage by , which is unique from the intracellular
4. damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
D) decreasing protein synthesis and function
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
A) destroying phospholipids in the cell membrane.
B) altering the immune response of the cell.
C) disrupting calcium storage in the cell.
D) inactivation of enzymes and mitochondria.
, 6. Injured acells ahave aimpaired aflow aof asubstances athrough athe acell amembrane aas aa aresult aof:
A) increased afat aload.
B) altered apermeability.
C) altered aglucose autilization.
D) increased asurface areceptors.
7. Reversible aadaptive aintracellular aresponses aare ainitiated aby:
A) stimulus aoverload.
B) genetic amutations.
C) chemical amessengers.
D) mitochondrial aDNA.
8. Injured acells abecome avery aswollen aas aa aresult aof:
A) increased acell aprotein asynthesis.
B) altered acell avolume aregulation.
C) passive aentry aof apotassium ainto athe acell.
D) bleb aformation ain athe aplasma amembrane.
A adiabetic apatient ahas aimpaired asensation, acirculation, aand aoxygenation aof ahis afeet. aHe
asteps aon aa apiece aof aglass, athe awound adoes anot aheal, aand athe aarea atissue abecomes
anecrotic. aThe anecrotic
9. cell adeath ais a characterized aby:
A) rapid aapoptosis.
B) cellular arupture.
C) shrinkage aand acollapse.
D) chronic ainflammation.
A a99-year-old awoman ahas aexperienced athe adecline aof acell afunction aassociated awith aage. aA
10. group aof atheories a of acellular aaging afocus aon aprogrammed:
A) changes awith agenetic ainfluences.
B) elimination aof acell areceptor asites.
C) insufficient atelomerase aenzyme.
D) DNA amutation aor afaulty arepair.
An a89-year-old afemale apatient ahas aexperienced asignificant adecreases ain aher amobility
aand astamina aduring aa a3-week ahospital astay afor athe atreatment aof aa afemoral ahead afracture.
aWhich aof athe afollowing aphenomena amost alikely aaccounts afor athe apatients adecrease ain
amuscle afunction
11. that aunderlies aher areduced amobility?
A) Impaired amuscle acell ametabolism aresulting afrom ametaplasia
B) Dysplasia aas aa aconsequence aof ainflammation aduring abone aremodeling
C) Disuse aatrophy aof amuscle a cells aduring aa aprolonged aperiod aof aimmobility
