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Terms in this set (83)
Drug Nomenclature
-Generic Name(identifies the active ingredient in the
drug)
-Trade/Brand Name(only used by company that
made the drug for 10 years)
Drug Preparations
-Capsule/Pill/Tablet
Pharmacology (ch 29)
-Enteric Coated (EC)
-Powder
-Elixir
-Solution
-Lotion
-Liniment
-Suppository
-Transdermal Patch
- Pharmacodynamics (what drug is manufactured to
do)
Drugs and the Body (Ch Pharmacokinetics (what are body does to that drug)
29) -absorption
-distribution: Gi tract, Iv, blood flow
-metabolism: liver
-excretion: kidneys
, How the drug works on the body:
•Replace or act as a substitute for missing chemicals
Pharmacodynamics
Drugs usually work in •To increase or stimulate certain cellular activities
four ways (Ch 29)
•To depress or slow cellular activities
•To interfere with the functioning of foreign cells
•Weight
- 2.2 lbs = 1 kilogram (1 kg)
•Age
•Gender
Factors Affecting Drug
•Genetic and cultural factors
Action (Ch 29)
•Psychological factors
•Pathology
•Environment
•Timing of administration
Absorption
Distribution
Pharmacokinetics
Metabolism
Excretion
•Lipid solubility
•pH
Factors Affecting
•Blood flow
Absorption of
•Local conditions at the site of administration
Medications
•Drug dosage
•Route of administration
, •Depend greatly on Route of administration
•Oral medications- First pass effect
•Parenteral - None, direct absorption into venous
system
•Intramuscular (IM)- perfusion, fat content,
temperature
•Subcutaneous (SQ) - perfusion, fat content,
temperature
Routes of Administration
•Per Rectum (PR)- perfusion, lesions, length of time
retained
•Mucous membrane (sublingual, buccal)- perfusion,
integrity, food, smoking, time retained
•Topical /Transdermal patch- perfusion, integrity of
skin,
•Inhalation - perfusion, integrity of lung lining, ability
to administer properly
◆Undesired Effects
-Unpleasant
-Dangerous
Adverse Drug Effects (ch
◆Reasons they occur
29)
-Other effect on body
-Sensitivity
-Drugs action
-Too much or too little dosage
•Allergic Effect
•Drug Tolerance
Adverse Drug Reactions
(ch 29)
•Toxic Effect
•Idiosyncratic/Paradoxical Effect
- Half life of a drug: the time it takes for drug in the
body to decrease to one half the peak level
Half Life (Ch 29)
- Half life is affected by absorption, distribution,
metabolism, and excretion