Maryville U. Pharm Nurs615 Exam 3 With Complete Answer,2025,Latest Upload....

MARYVILLE U. PHARM NURS615 EXAM 3 COMPLETE QUESTIONS & n n n n n n n n




ANSWERS (100% VERIFIED SOLUTIONS) 2025/2026 UPDATE
n n n n n n




What hormones are produced by the adrenal gland and maintain homeostasis? - CORRECT ANSWER
n n n n n n n n n n n n n




-Corticosteroids/glucocorticoids/steroids
n




What is an endogenous glucocorticoid? - CORRECT ANSWER -Cortisol
n n n n n n n n




What are the 3 categories of steroid hormones? - CORRECT ANSWER -1. Glucocorticoids
n n n n n n n n n n n n




2. Mineralcorticoids

3. Adrenal Sex Hormones n n




What is the MOA of corticosteroids? - CORRECT ANSWER -1. Inhibits the immune and inflammatory
n n n n n n n n n n n n n n




system
n




2. Inhibits arachidonic acid metabolism
n n n




3. Inhibits production of ILK-1, TNF, and other cytokines
n n n n n n n




4. Impairs lymphocytes and inhibits tissue repair
n n n n n




Examples of glucocorticoid medications - CORRECT ANSWER -hydrocortisone, prednisone,
n n n n n n n n




methyprednisolone, dexamethasone
n n




What is long-term glucocorticoid use indicated for? - CORRECT ANSWER -Life-threatening
n n n n n n n n n n




conditions or severe disabling symptoms
n n n n n




What is short-term glucocorticoid use indicated for? - CORRECT ANSWER -Self-limiting conditions
n n n n n n n n n n n

,What are the adverse effects of glucocorticoids after 6 months of use? - CORRECT ANSWER -1.
n n n n n n n n n n n n n n n




Osteoporosis
n




2. Worsens diabetic control and increases blood glucose (diabetics need more insulin)
n n n n n n n n n n




3. Promotes gastric secretion and causes abdominal pain, N/V (Report black tarry stools)
n n n n n n n n n n n




When does bone density begin to decline because of a decrease in calcium from
n n n n n n n n n n n n n




glucocorticosteroid use? - CORRECT ANSWER -Within the first 3 months
n n n n n n n n n n




General adverse effects of glucocorticosteroids - CORRECT ANSWER -1. Retains sodium and
n n n n n n n n n n n




water
n




2. Increases appetite n




3. Promotes fat deposit in cervical area and face n n n n n n n




4. Increases uric acid n n




5. Delerium, insomnia, mood alterations, anxiety n n n n




6. Adrenal suppression n




7. Poor wound healing, thin skin, acne, ocular damage
n n n n n n n




Why must glucocorticosteroids be tapered? - CORRECT ANSWER -1.To avoid recurrent activity of
n n n n n n n n n n n n n




underlying disease
n n




2. To avoid possible cortisol deficiency resulting from the HPA axis and HPA suppression during
n n n n n n n n n n n n n n




steroid therapy
n n




How should glucocorticosteroids be discontinued? - CORRECT ANSWER -1. Administer for short
n n n n n n n n n n n




courses and then taper; do NOT abruptly withdrawal
n n n n n n n n




When is the ideal time to administer prednisone? - CORRECT ANSWER -In the morning
n n n n n n n n n n n n n




When are glucocorticosteroids contraindicated? - CORRECT ANSWER -1. Severe infections
n n n n n n n n n

,2. Allergy
n




What is patient education for glucocorticosteroid use? - CORRECT ANSWER -1. Low carb, low
n n n n n n n n n n n n n




sodium, and high protein diet
n n n n n




2. Increase calcium and vitamin D
n n n n n




3. Monitor weight, edema, blood glucose, blood pressure, potassium, electrolytes, and CBC
n n n n n n n n n n n




What is the MOA of colchicine? - CORRECT ANSWER -Decreases inflammation by decreasing the
n n n n n n n n n n n n n




movement of leukocytes into tissues containing urate crystals -- this affects the way the body responds
n n n n n n n n n n n n n n n n




to the uric acid -- DECREASES swelling and pain
n n n n n n n n n




What is the indication of colchicine? - CORRECT ANSWER -Prophylaxis of gout flares in adults (or to
n n n n n n n n n n n n n n n n




treat Behcets syndrome)
n n n




Is colchicine curative? - CORRECT ANSWER -Not a cure and does not prevent the disease from
n n n n n n n n n n n n n n n




progressing
n




What is low-dose colchicine? - CORRECT ANSWER -1.2mg followed by 0.6mg 1 hr later (for 1.8mg
n n n n n n n n n n n n n n n




total)
n




What is high-dose colchicine? - CORRECT ANSWER -1.2mg followed by 0.6mg every 4-6hours (for
n n n n n n n n n n n n n




4.8mg total)
n n




Is high or low-dose colchicine preferred? - CORRECT ANSWER -Low-dose is AS EFFECTIVE as
n n n n n n n n n n n n n




high-dose with LESS side effects
n n n n n




What is the main side effect of colchicine? - CORRECT ANSWER -DIARRHEA (make sure this is in
n n n n n n n n n n n n n n n n




patient teaching)
n n

, What is the MOA of allopurinol (Zyloprim)? - CORRECT ANSWER -Prevents formation of uric acid by
n n n n n n n n n n n n n n n




inhibiting xanthine oxidase
n n n




How often is allopurinol (Zyloprim) taken? - CORRECT ANSWER -Taken DAILY to prevent formation of
n n n n n n n n n n n n n n




uric acid crystals
n n n




What is important patient teaching for febuxostat (Uloric)? - CORRECT ANSWER -Gout may worsen
n n n n n n n n n n n n n




initially with therapy
n n n




What should treatment with febuxostat (Uloric) be combined with for the first 6 months? - CORRECT
n n n n n n n n n n n n n n n




ANSWER -Patients should be treated with NSAIDs concurrently
n n n n n n n n




What are the lab values to monitor in gout? - CORRECT ANSWER -1. BUN
n n n n n n n n n n n n n




2. Creatinine

3. LFTs (most anti-gout meds can be associated with hepatotoxicity
n n n n n n n n




4. Uric acid levels n n




What is the MOA of uricosuric agents? - CORRECT ANSWER -Inhibit renal tubular reabsorption of
n n n n n n n n n n n n n n




urate = increased renal excretion of uric acid
n n n n n n n n




What are examples of uricosuric agents? - CORRECT ANSWER -Probenecid and sulfinpyrazone
n n n n n n n n n n n




What type of diet should be avoided in patients with gout? - CORRECT ANSWER -Alkaline diet to reduce
n n n n n n n n n n n n n n n n n




urates; NO liver, kidney, anchovies, scallops, trout, codfish, mussels, and bacon
n n n n n n n n n n n




What should not be used in combination with probenecid? - CORRECT ANSWER -NO ASA or
n n n n n n n n n n n n n n




salicylates
n