TOXICOLOGY (GREEN PACOP)
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1. This is obtained from an examination of the tissues and organs of the dead.
a. Experimental evidence c. post-mortem evidence
b. Chemical evidence d. circumstantial evidence: c. post-mortem evidence
2. Death may result from poisoning due to the following causes, except: a. due
to interference with the carriage of oxygen
b. due to inhibition of the respiratory movements by neuro muscular agents
c. due to interference with the enzyme system utilizing it
d. circulatory failure as a result of cardiac glucosides: c. due to interference with the enzyme
system utilizing it
3. The most serious potential consequence of ingestion of liquid hydrocarbon
such as kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. the aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison: b. the aspiration of the poison into the respiratory
tract
4. The specific antidote for the treatment of poisoning due to oral ingestion of
silver nitrate would be the oral administration of :
a. acetic acid solution
b. normal saline
c. sodium bicarbonate: b. normal saline
5. Catharsis as a way of removing a poison include the ff. except:
a. increases intestinal injury when a corrosive is ingested
b. is avoided in a patient showing disturbed electrolyte imbalance
c. hypertonic cathartic and enemas are hazardous in the presence of impaired
renal function
d. none of the above: d. none of the above
6. This is recommended in phenol poisoning as a cathartic but is contraindicated
in poisoning by chlorinated insecticide, since it may increase intestinal absorp-
tion
a. magnesium sulfate c. mannitol
b. castor oil d. Fleet's Phospho-soda: b. castor oil
, TOXICOLOGY (GREEN PACOP)
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7. A poison which increases suddenly in its intensity of action after slow or
gradual addition of it is
a. corrosive poison c. true poison
b. cumulative poison d. irritant poison: b. cumulative poison
8. Streptomycin can cause:
a. 4th cranial damage c. 8th cranial damage
b. 7th cranial damage d. 6th cranial damage: c. 8th cranial damage
9. Most accidental poisoning in children is caused by:
a. detergents
b. bleaches
c. crayons
d. insecticides
e. salicylate analgesics: c. crayons
10. Antidote for iodine poisoning:
a. silver nitrate c. potassium nitrate
b. starch d. sugar: b. starch
11. The evidences to be saved in nonfatal poisoning are the following, except:
a. lung d. blood
b. urine e. body fat
c. food: a. lung
12. A specialized field of toxicology that designates an area of professional
emphasis within the realm of medical science.
a. Forensic toxicology c. Environmental toxicology
b. Clinical toxicology d. Regulatory toxicology: b. Clinical toxicology
13. This is an area of toxicology which is concerned directly with toxicity testing,
which provides necessary information for safety evaluation and regulatory
requirements.
a. mechanistic toxicology c. descriptive toxicology
b. regulatory toxicology d. forensic toxicology: c. descriptive toxicology
14. The quantity of medicine that can kill an organism
a. fatal dose c. Teratology
b. LD50 d. Threshold Limit Value: a. fatal dose
, TOXICOLOGY (GREEN PACOP)
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15. Acute poisoning includes, except:
a. taking a strong poison
b. taking several small doses but frequent
c. taking several small doses at long intervals
d. taking excessive single doses: c. taking several small doses at long intervals
16. When reporting cases of poisoning like eating in a public restaurant, the
cases should be reported to the:
a. nurse d. public health officer
b. family doctor e. BFAD
c. pharmacist: d. public health officer
17. The ff. are mechanism of poison absorption, except:
a. hydrolysis c. filtration
b. endocytosis d. passive diffusion: a. hydrolysis
18. An example of a Phase 1 Reaction in the metabolism of substances is/are:
a. oxidation c. reduction
b. hydrolysis d. all of the above: d. all of the above
19. Pneumomediasternum is a complication of the use of:
a. gastric lavage c. hemoperfusion
b. hemodialysis d. emetics: a. gastric lavage
20. Constipation caused by active charcoal can be relieved by concomitant ad-
ministration of
a. glycerol c. laxative
b. water d. none of the above: c. laxative
21. Contraindication to the use of cathartics are the ff. except:
a. GI hemorrhage c. renal failure
b. corrosive agents d. none of the above: d. none of the above
22. The percentage of oxygen which is indicated for carbon dioxide poisoning to
increase the conversion of carboxyhemoglobin to hemoglobin and myoglobin
and to increase oxygen saturation of the plasma is:
a. 50% c. 100%
b. 75% d. 10%: c. 100%
, TOXICOLOGY (GREEN PACOP)
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23. Nail polish removers contain
a. aniline c. acetone
b. ammonium hydroxide d. phosphoric acid: c. acetone
24. Convulsions caused by drug poisoning are most commonly associated with:
a. Phenobarbital c. strychnine
b. diazepam d. chlorpromazine: c. strychnine
25. Alkanizing the urine with sodium bicarbonate is useful in the treatment of
poisoning with:
a. ASA and barbiturates c. amphetamines
b. phencyclidine d. morphine: a. ASA and barbiturates
26. Activated charcoal may be used in the treatment of these poisoning, except
a. Phenobarbital c. aspirin
b. propoxyphene d. methanol: d. methanol
27. These statements regarding carbon monoxide poisoning are true except:
a. the oxygen carrying capacity of the blood is decreased
b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing
less oxygen to the tissues
c. carboxyhemoglobin level of less than 30% produces minimal symptoms
d. treatment with 100% carbon dioxide is effective: d. treatment with 100% carbon dioxide
is effective
28. Ototoxicity may be an adverse reaction of the following, except:
a. streptomycin c. furosemide
b. ethacrynic acid d. tetracyclines: d. tetracyclines
29. The major routes by which toxic agents gain access to the body are through
the ff., except:
a. blood d. skin
b. GIT e. parenteral route
c. lungs: a. blood
30. Acute exposure by inhalation refers to continuous exposure for less than 2
hours, most frequently for:
a. 2 d. 5
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1. This is obtained from an examination of the tissues and organs of the dead.
a. Experimental evidence c. post-mortem evidence
b. Chemical evidence d. circumstantial evidence: c. post-mortem evidence
2. Death may result from poisoning due to the following causes, except: a. due
to interference with the carriage of oxygen
b. due to inhibition of the respiratory movements by neuro muscular agents
c. due to interference with the enzyme system utilizing it
d. circulatory failure as a result of cardiac glucosides: c. due to interference with the enzyme
system utilizing it
3. The most serious potential consequence of ingestion of liquid hydrocarbon
such as kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. the aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison: b. the aspiration of the poison into the respiratory
tract
4. The specific antidote for the treatment of poisoning due to oral ingestion of
silver nitrate would be the oral administration of :
a. acetic acid solution
b. normal saline
c. sodium bicarbonate: b. normal saline
5. Catharsis as a way of removing a poison include the ff. except:
a. increases intestinal injury when a corrosive is ingested
b. is avoided in a patient showing disturbed electrolyte imbalance
c. hypertonic cathartic and enemas are hazardous in the presence of impaired
renal function
d. none of the above: d. none of the above
6. This is recommended in phenol poisoning as a cathartic but is contraindicated
in poisoning by chlorinated insecticide, since it may increase intestinal absorp-
tion
a. magnesium sulfate c. mannitol
b. castor oil d. Fleet's Phospho-soda: b. castor oil
, TOXICOLOGY (GREEN PACOP)
Study online at https://quizlet.com/_hwxi5p
7. A poison which increases suddenly in its intensity of action after slow or
gradual addition of it is
a. corrosive poison c. true poison
b. cumulative poison d. irritant poison: b. cumulative poison
8. Streptomycin can cause:
a. 4th cranial damage c. 8th cranial damage
b. 7th cranial damage d. 6th cranial damage: c. 8th cranial damage
9. Most accidental poisoning in children is caused by:
a. detergents
b. bleaches
c. crayons
d. insecticides
e. salicylate analgesics: c. crayons
10. Antidote for iodine poisoning:
a. silver nitrate c. potassium nitrate
b. starch d. sugar: b. starch
11. The evidences to be saved in nonfatal poisoning are the following, except:
a. lung d. blood
b. urine e. body fat
c. food: a. lung
12. A specialized field of toxicology that designates an area of professional
emphasis within the realm of medical science.
a. Forensic toxicology c. Environmental toxicology
b. Clinical toxicology d. Regulatory toxicology: b. Clinical toxicology
13. This is an area of toxicology which is concerned directly with toxicity testing,
which provides necessary information for safety evaluation and regulatory
requirements.
a. mechanistic toxicology c. descriptive toxicology
b. regulatory toxicology d. forensic toxicology: c. descriptive toxicology
14. The quantity of medicine that can kill an organism
a. fatal dose c. Teratology
b. LD50 d. Threshold Limit Value: a. fatal dose
, TOXICOLOGY (GREEN PACOP)
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15. Acute poisoning includes, except:
a. taking a strong poison
b. taking several small doses but frequent
c. taking several small doses at long intervals
d. taking excessive single doses: c. taking several small doses at long intervals
16. When reporting cases of poisoning like eating in a public restaurant, the
cases should be reported to the:
a. nurse d. public health officer
b. family doctor e. BFAD
c. pharmacist: d. public health officer
17. The ff. are mechanism of poison absorption, except:
a. hydrolysis c. filtration
b. endocytosis d. passive diffusion: a. hydrolysis
18. An example of a Phase 1 Reaction in the metabolism of substances is/are:
a. oxidation c. reduction
b. hydrolysis d. all of the above: d. all of the above
19. Pneumomediasternum is a complication of the use of:
a. gastric lavage c. hemoperfusion
b. hemodialysis d. emetics: a. gastric lavage
20. Constipation caused by active charcoal can be relieved by concomitant ad-
ministration of
a. glycerol c. laxative
b. water d. none of the above: c. laxative
21. Contraindication to the use of cathartics are the ff. except:
a. GI hemorrhage c. renal failure
b. corrosive agents d. none of the above: d. none of the above
22. The percentage of oxygen which is indicated for carbon dioxide poisoning to
increase the conversion of carboxyhemoglobin to hemoglobin and myoglobin
and to increase oxygen saturation of the plasma is:
a. 50% c. 100%
b. 75% d. 10%: c. 100%
, TOXICOLOGY (GREEN PACOP)
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23. Nail polish removers contain
a. aniline c. acetone
b. ammonium hydroxide d. phosphoric acid: c. acetone
24. Convulsions caused by drug poisoning are most commonly associated with:
a. Phenobarbital c. strychnine
b. diazepam d. chlorpromazine: c. strychnine
25. Alkanizing the urine with sodium bicarbonate is useful in the treatment of
poisoning with:
a. ASA and barbiturates c. amphetamines
b. phencyclidine d. morphine: a. ASA and barbiturates
26. Activated charcoal may be used in the treatment of these poisoning, except
a. Phenobarbital c. aspirin
b. propoxyphene d. methanol: d. methanol
27. These statements regarding carbon monoxide poisoning are true except:
a. the oxygen carrying capacity of the blood is decreased
b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing
less oxygen to the tissues
c. carboxyhemoglobin level of less than 30% produces minimal symptoms
d. treatment with 100% carbon dioxide is effective: d. treatment with 100% carbon dioxide
is effective
28. Ototoxicity may be an adverse reaction of the following, except:
a. streptomycin c. furosemide
b. ethacrynic acid d. tetracyclines: d. tetracyclines
29. The major routes by which toxic agents gain access to the body are through
the ff., except:
a. blood d. skin
b. GIT e. parenteral route
c. lungs: a. blood
30. Acute exposure by inhalation refers to continuous exposure for less than 2
hours, most frequently for:
a. 2 d. 5