Half-life of Tc99 6 hours
Half-life of Mo99 66 hours
Half-life of In-111 67 hours
Half-life of Tl-201 73 hours
Half-life of Ga-67 78 hours
Half-life of I-123 13 hours
Half-life of Xe-133 5.3 days
Half-life of I-131 8 days
Half-life of F-18 110 minutes
Half-life of Ga-68 68 minutes
Half-life of Rb-82 75 seconds
Half-life of Lu-177 6.7 days
* 1-10 Gy
* infection, bleeding, bone marrow failure
Hemopoatic (Bone Marrow) Syndrome
* low WBC, low plateletes, infections, bruising
* 2-6 weeks
* 10-50 Gy
* GI destruction, sepsis
Gastrointestinal (GI) Syndrome
* nasuea, vomitting, bloody direara, dehydration
* 3-10 days
* greater than 50 Gy
* brain swelling
Cerebrovascular (CVS) Syndrome
* seizures, unconciousness
* hours to 1-2 days
DOT White 1 less than 0.5 mrem/hr
DOT Yellow 2 0.5-50 mrem/hr
, DOT Yellow 3 50-200 mrem/hr
Bone Scan 20-30mci MDP/HDP
* 10-20mci of Xe133
Lung Ventilation
* 25-40mci of DTPA
Lung Perfusion 2-6mci MAA
Liver/Spleen 2-7mci sc
1mci of SC
Gastric Emptying 20uci DTPA
125uci In111 DTPA
20-30mci RBC
GI Bleed Scan
10-20 mci SC
100-450uci I-123
Thyroid Uptake
1uci-10mci I-131
100-450uci I-123
Thyroid Scan
1uci-10mci I-131
Renal ERPF 3-15mci MAG3
Renal GFR 3-15mci DTPA
Renal Cortical 1-6mci DMSA
Lymphstigraphy 200uci-2mci SC
HMPAO
Infection/Inflammation
In-111
3-6mci inflammation
Gallium Scan 8-10mci tumors
Ga67 Citrate
HAMA Human Anti-Mouse Antibody
ALARA As Low As Reasonably Achievable
, NRC Nuclear Regulatory Commission
HIPAA Health Insurance Portability and Accountability Act
PET Positron Emission Tomography
MRI Magnetic Resonance Imaging
CT Computed Tomography
SPECT Single Photon Emission Computed Tomography
Inverse Square Law (i1)(D1) ^2 = (i2)(D2) ^2
the amount of absorbing material that will reduce the
Half Value Layer
intensity of the primary beam to one-half its original value
1. notify all personnel in vicinity
2. contain spill with absorbent paper
3. remove contanminated clothing
Small Spills
4. place material into plastic bag > radioactive-waste
5. survey meter/wipe test
6. report to RSO
1. clear the area immediatley
2. use absorbent paper
Large Spills 3. remove contanminated clothing
4. evacuate and close all doors
5. notify RSO immediatley
Order for putting ON PPE gown, mask, goggles, gloves
Order for taking OFF PPE gloves, goggles, gown, mask
Antidote for Adenosine Aminophylline
0.02ug/kg
Cholecystokinin (CCK)
contract gall bladder
0.04mg/kg IV over 2-3min
Morphine
contracts sphincter of oddi
, Antidote for Dipyridamole Aminophylline
diuretic
Lasix Flurosemide
20-40mg over 1 min
Whole Body Dose Limit 5 rem (50 mSv)
Lens of Eye Dose Limit 15rem (150mSv)
Organ/Tissue Dose Limit 50rem (500mSv)
Skin/Extremeties Dose Limit 50rem (500mSv)
General Public 0.1rem (1mSv)
Embryo/Fetus 0.5rem (5 mSv)
Al3+ concentration no greater than 10ug/mL
Half-Life: 64.2 hours
Y-90 Microspheres / Theraspheres Diameter: 20um-30um
2-4mci of MAA through hepatic artery prior
- parkinsons
- 5mci IV
F-18 Flurodopa
- 150mg Carbidopa given orally 60-120mins before
- image 80mins post injection
- Alzehimers
F-18 Florbetapir Amyvid - 10mci in 10mL or less
- image 30-50 mins post injection
- prostate cancer
F-18 Fluciclovine (Axumin) - 10 mci bolus
- image 3 to 5mins post injections
What is F-18 Flurodeoxyglucose used for?
What is Lu-177 PMSA used for?
What is Sr-82 / Rb-82 used for?