APEA Pre-Predictor Exam 2025–2026 | 850+ Verified Questions
with Detailed Rationales | 100% Correct & Graded A+
Ai6iyoihadianiacuteionsetiofifever,ipharyngitis,iandiheadachei2idaysiago.iToday,ih
eipresentsiwithicervicalilymphadenopathyiandisandpaperitexturedirashieverywhe
reiexceptionihisiface.iAirapidistreptococcaliantigenitestiisipositive.iTheiremainder
iofitheiassessmentiiniunremarkable.iWhatiisitheimostilikelyidiagnosisianditheimo
stiappropriateiaction?i-ianswer-Scarletifever;itreatiwithiantibiotics.
ThisidiseaseiisidueitoiinfectioniwithiGroupiAiBeta-
hemolyticistreptococcus.iTheirashiisithoughtitoibeidueitoiaisystemicireactionitoit
heitoxiniproducedibyitheimicroorganism.iTheirashifadesiwithipressureiandiultim
atelyidesquamates.iAideep,inonblanchingirashionitheiflexorisurfacesiofitheiskinii
sireferreditoiasipastiailines.
Aipatientihasibeenidiagnosediwithihypothyroidismiandithyroidihormoneireplace
mentitherapyiisiprescribed.iWhenishoulditheinurseipractitionericheckitheipatien
t'siTSH?i-ianswer-6iweeks.
Theihalf-
lifeiofilevothyroxine,itheitreatmentiofichoiceiforithyroidireplacement,iisi7idays.i
Theiearliestithatimeaningfulichangesiwillibeiobservediisiati4-
6iweeks.iTherefore,itheiNPishouldiwaitiaiminimumiofi4-
6iweeksibeforeicheckingitheipatient'siTSH.
Ai15iyoimalueihasiaihistoryioficryptorchidismiwhichiwasisurgicallyirepaired.iBec
auseiofithisiinformation,iitiisiessentialiforitheinurseipractitioneritoiteachihimiabo
ut:i-ianswer-testiculariself-iexamination.
Cryptorchidism,ieveniwithisurgicalirepair,iisiassociatediwithiincreasediriskiforitestic
ularicancer.
Theitreatmentiofichoiceiforichronicibacterialiprostatitisi(CBP)iis:i-
ianswer-aiflouroquinoloneitwiceidailyifori3iweeksitoi4imonths.
Theitreatmentiofichiceiisiaiflouroquinoloneitwiceidailyifori3iweeksitoi4imonth
s.iTheicureirateiwithiBactrim-DSiisionlyiabouti30-40%.
,Ai25iyoifemaleihasiaihistoryiofifrequenticandidalivaginaliinfectionsiinitheipastiye
ar.iSheiisiiniaimonogamousisexualirelationshipiandiusesiandiIUDiforicontracepti
on.iOfitheifollowing,iwhichiisitheimostilikelyiunderlyingiconiditionipredisposingi
heritoirecurringicandidalivaginitis?i-ianswer-Diabetes.
Aicommoniunderlyingicauseiofifrequentiinfectionsiisidiabetesimellitus.iPregnan
cyiincreasesitheiincidenceioficandidiasis,ibutiisiunlikelyiaifactoriwithithisipatient
.
,WhichiofitheifollowingiisiNOTiaicharacteristiciofitheiS3iheartisound?i-ianswer-
Theisoundiisihigh-pitchediandioccursijustiprioritoitheiS1iheartisound.
TheiS3iheartisoundiisilow-
pitchediandioccursijustiafteritheiS2iheartisound.iItiisiproducedibyirapidiventricul
arifillingiandiisibestiauscultatediinitheimitraliarea.iItiisiaicommonifindingiwithirig
ht-sidediheartifailure,irapidigrowth,ianditheilastitrimesteriofipregnancy.
FollowingitheifindingiofiprostateiglandiabnormalitiesioniDRE,itheiNPiordersithei
appropriateilabs.iWhemipreparingitoireviewilabireportsiwithitheipatient,itheinurs
eipractitioneriknowsialliofitheifollowingiareitrueiEXCEPT:i-ianswer-
normaliPSAiisi10ng/mlioriless.
NormaliPSAiisi4ng/mlioriless.iPSAilevelsigreaterithei4iandilessithani10iareiassoci
atediwithiBPH.iAi10iorigreateriPSAilevelisuggestsiprostateicancer.iPositiveiseru
miacidiphosphataseiisiassociatediwithimalignancyiofitheiprostateiglandiwithibon
eimetasasis.
Ai66iyoifemaleipresentsitoiyouriclinic.iSheistatesithatiyesterdayieveningisheihadic
hestipainifori20-
30iminutes.iWhichifindingimostistronglyicorrelatesiwithimyocardialiinfarction?i-
ianswer-ElevatediTroponiniIilevels
Anielevatedicreatinineikinasei(CK)iisinotidiagnosticiofiaimyocardialiinfarctioni( MI).iCKimayibeielevatedifromianiIMiinjection,isurgery,iotianyitypeiofiextensiveis
keletalimuscleitraumaioriprolonged,istrenuousiphysicaliexertion.iSTisegmentide pressionioniEKGiusuallyiindicatesianiischemicimyocardium,ibut,inotinecessaril
y,ioneipost-MI.iElevatediSTiseghmentsireflectimycardialidamage.iMBibandsiareispecificifor
imyocardialismoothimuscle.iIfitheseiareielevated,itheipatientiMAYiHAVEihadiaiv eryirecentiMI.iTheimostiaccurateimarkerioficardiacidamage,ibecauseiitiisimoreis
pecificiandisensitiveithaniCKiMB,iisiaitroponinimeasurement.
Whatiisiaisecondaryicauseiofihyperlipidemia?i-ianswer-hypothyroidism
Hypothyroidismiisiaicommonisecondaryicauseiofihyperlipidemia.iInitheievaluat
ioniofiaipatientiwithihyperlipidemia,iaiTSHishouldialwaysibeicheckediandicorrec
tedibeforeiattemptingitreatmentiforihyperlipidemia.iOtheripossibleicausesiofisec
ondayihyperlipidemiaiincludeipregnancy,iexcessiveiweightigain,iexcessiveialcoh
, oliintake,iinsuliniresistanceiorideficiency,iobstructiveiliveridisease,iandiuremia.
Someimedicationsicaniproduceisecondaryihypothyroidismitoo:ithiazideidiuretic
s,isomeibeta-blockers,ioralicontraceptives,iandicorticosteroids.
Ai35-
yoimaleipresentsiwithiaicomplaintiofilowipelvicipain,idysuria,ihesitancy,iurgency,
iandireducediforiofistream.iTheinurseipractitionerisuspectsiacuteibacterialiprostat
itis.iTheiNPiwouldiappropriatelyicollectialliofitheifollowingispecimensiEXCEPTi
a:isterileiin-and-outicatheteriurineispecimen.i-ianswer-Aisterile
in-and-
outicatheterispecimeniwouldiidentifyionlyiorganismsiinitheibladderiandiwouldinotidi
fferentiate
with Detailed Rationales | 100% Correct & Graded A+
Ai6iyoihadianiacuteionsetiofifever,ipharyngitis,iandiheadachei2idaysiago.iToday,ih
eipresentsiwithicervicalilymphadenopathyiandisandpaperitexturedirashieverywhe
reiexceptionihisiface.iAirapidistreptococcaliantigenitestiisipositive.iTheiremainder
iofitheiassessmentiiniunremarkable.iWhatiisitheimostilikelyidiagnosisianditheimo
stiappropriateiaction?i-ianswer-Scarletifever;itreatiwithiantibiotics.
ThisidiseaseiisidueitoiinfectioniwithiGroupiAiBeta-
hemolyticistreptococcus.iTheirashiisithoughtitoibeidueitoiaisystemicireactionitoit
heitoxiniproducedibyitheimicroorganism.iTheirashifadesiwithipressureiandiultim
atelyidesquamates.iAideep,inonblanchingirashionitheiflexorisurfacesiofitheiskinii
sireferreditoiasipastiailines.
Aipatientihasibeenidiagnosediwithihypothyroidismiandithyroidihormoneireplace
mentitherapyiisiprescribed.iWhenishoulditheinurseipractitionericheckitheipatien
t'siTSH?i-ianswer-6iweeks.
Theihalf-
lifeiofilevothyroxine,itheitreatmentiofichoiceiforithyroidireplacement,iisi7idays.i
Theiearliestithatimeaningfulichangesiwillibeiobservediisiati4-
6iweeks.iTherefore,itheiNPishouldiwaitiaiminimumiofi4-
6iweeksibeforeicheckingitheipatient'siTSH.
Ai15iyoimalueihasiaihistoryioficryptorchidismiwhichiwasisurgicallyirepaired.iBec
auseiofithisiinformation,iitiisiessentialiforitheinurseipractitioneritoiteachihimiabo
ut:i-ianswer-testiculariself-iexamination.
Cryptorchidism,ieveniwithisurgicalirepair,iisiassociatediwithiincreasediriskiforitestic
ularicancer.
Theitreatmentiofichoiceiforichronicibacterialiprostatitisi(CBP)iis:i-
ianswer-aiflouroquinoloneitwiceidailyifori3iweeksitoi4imonths.
Theitreatmentiofichiceiisiaiflouroquinoloneitwiceidailyifori3iweeksitoi4imonth
s.iTheicureirateiwithiBactrim-DSiisionlyiabouti30-40%.
,Ai25iyoifemaleihasiaihistoryiofifrequenticandidalivaginaliinfectionsiinitheipastiye
ar.iSheiisiiniaimonogamousisexualirelationshipiandiusesiandiIUDiforicontracepti
on.iOfitheifollowing,iwhichiisitheimostilikelyiunderlyingiconiditionipredisposingi
heritoirecurringicandidalivaginitis?i-ianswer-Diabetes.
Aicommoniunderlyingicauseiofifrequentiinfectionsiisidiabetesimellitus.iPregnan
cyiincreasesitheiincidenceioficandidiasis,ibutiisiunlikelyiaifactoriwithithisipatient
.
,WhichiofitheifollowingiisiNOTiaicharacteristiciofitheiS3iheartisound?i-ianswer-
Theisoundiisihigh-pitchediandioccursijustiprioritoitheiS1iheartisound.
TheiS3iheartisoundiisilow-
pitchediandioccursijustiafteritheiS2iheartisound.iItiisiproducedibyirapidiventricul
arifillingiandiisibestiauscultatediinitheimitraliarea.iItiisiaicommonifindingiwithirig
ht-sidediheartifailure,irapidigrowth,ianditheilastitrimesteriofipregnancy.
FollowingitheifindingiofiprostateiglandiabnormalitiesioniDRE,itheiNPiordersithei
appropriateilabs.iWhemipreparingitoireviewilabireportsiwithitheipatient,itheinurs
eipractitioneriknowsialliofitheifollowingiareitrueiEXCEPT:i-ianswer-
normaliPSAiisi10ng/mlioriless.
NormaliPSAiisi4ng/mlioriless.iPSAilevelsigreaterithei4iandilessithani10iareiassoci
atediwithiBPH.iAi10iorigreateriPSAilevelisuggestsiprostateicancer.iPositiveiseru
miacidiphosphataseiisiassociatediwithimalignancyiofitheiprostateiglandiwithibon
eimetasasis.
Ai66iyoifemaleipresentsitoiyouriclinic.iSheistatesithatiyesterdayieveningisheihadic
hestipainifori20-
30iminutes.iWhichifindingimostistronglyicorrelatesiwithimyocardialiinfarction?i-
ianswer-ElevatediTroponiniIilevels
Anielevatedicreatinineikinasei(CK)iisinotidiagnosticiofiaimyocardialiinfarctioni( MI).iCKimayibeielevatedifromianiIMiinjection,isurgery,iotianyitypeiofiextensiveis
keletalimuscleitraumaioriprolonged,istrenuousiphysicaliexertion.iSTisegmentide pressionioniEKGiusuallyiindicatesianiischemicimyocardium,ibut,inotinecessaril
y,ioneipost-MI.iElevatediSTiseghmentsireflectimycardialidamage.iMBibandsiareispecificifor
imyocardialismoothimuscle.iIfitheseiareielevated,itheipatientiMAYiHAVEihadiaiv eryirecentiMI.iTheimostiaccurateimarkerioficardiacidamage,ibecauseiitiisimoreis
pecificiandisensitiveithaniCKiMB,iisiaitroponinimeasurement.
Whatiisiaisecondaryicauseiofihyperlipidemia?i-ianswer-hypothyroidism
Hypothyroidismiisiaicommonisecondaryicauseiofihyperlipidemia.iInitheievaluat
ioniofiaipatientiwithihyperlipidemia,iaiTSHishouldialwaysibeicheckediandicorrec
tedibeforeiattemptingitreatmentiforihyperlipidemia.iOtheripossibleicausesiofisec
ondayihyperlipidemiaiincludeipregnancy,iexcessiveiweightigain,iexcessiveialcoh
, oliintake,iinsuliniresistanceiorideficiency,iobstructiveiliveridisease,iandiuremia.
Someimedicationsicaniproduceisecondaryihypothyroidismitoo:ithiazideidiuretic
s,isomeibeta-blockers,ioralicontraceptives,iandicorticosteroids.
Ai35-
yoimaleipresentsiwithiaicomplaintiofilowipelvicipain,idysuria,ihesitancy,iurgency,
iandireducediforiofistream.iTheinurseipractitionerisuspectsiacuteibacterialiprostat
itis.iTheiNPiwouldiappropriatelyicollectialliofitheifollowingispecimensiEXCEPTi
a:isterileiin-and-outicatheteriurineispecimen.i-ianswer-Aisterile
in-and-
outicatheterispecimeniwouldiidentifyionlyiorganismsiinitheibladderiandiwouldinotidi
fferentiate
