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Maryville NURS 623 Exam 3, 2025: Psychiatric Mental Health & Advanced Pharmacology
1. A patient with Major Depressive Disorder is prescribed fluoxetine (Prozac). The PMHNP
should provide which key teaching point regarding the timeline for therapeutic effect?
A) "You should feel significantly better within 24-48 hours."
B) "Therapeutic effects can take 4-6 weeks to be fully realized."
C) "This medication works immediately to correct a chemical imbalance."
D) "If you don't feel better after one week, the dose will be doubled."
2. Which of the following is the primary neurotransmitter targeted by Benzodiazepines for
their anxiolytic effect?
A) Serotonin
B) Norepinephrine
C) Dopamine
D) Gamma-aminobutyric acid (GABA)
3. A patient taking lithium for Bipolar I Disorder presents with nausea, vomiting, and coarse
hand tremors. Their lithium level is 2.0 mEq/L. The PMHNP recognizes this as:
A) Therapeutic response
B) Lithium toxicity
C) Serotonin syndrome
D) Neuroleptic Malignant Syndrome
4. The first-line, gold-standard pharmacological treatment for Acute Psychotic Episodes in
Schizophrenia is:
A) Benzodiazepines
B) Mood Stabilizers
C) First-Generation (Typical) Antipsychotics
D) Second-Generation (Atypical) Antipsychotics
,5. Which assessment finding is most critical to monitor in a patient taking Clozapine (Clozaril)?
A) Fasting Blood Glucose
B) Agranulocytosis (low WBC count)
C) Thyroid Function Tests
D) Liver Function Tests
6. A patient experiencing negative symptoms of Schizophrenia (e.g., avolition, flat affect)
would likely have the best response to which antipsychotic?
A) Haloperidol (Haldol)
B) Chlorpromazine (Thorazine)
C) Aripiprazole (Abilify)
D) Benztropine (Cogentin)
7. The mechanism of action for Selective Serotonin Reuptake Inhibitors (SSRIs) primarily
involves:
A) Blocking dopamine D2 receptors
B) Inhibiting the reuptake of serotonin into the presynaptic neuron
C) Blocking NMDA glutamate receptors
D) Enhancing GABAergic inhibition
8. Which medication is an FDA-approved treatment for reducing the risk of suicide in patients
with Schizophrenia?
A) Olanzapine (Zyprexa)
B) Clozapine (Clozaril)
C) Risperidone (Risperdal)
D) Quetiapine (Seroquel)
9. A patient taking an SSRI develops high fever, confusion, muscle rigidity, and autonomic
instability. The PMHNP suspects:
A) Lithium Toxicity
B) Anticholinergic Crisis
C) Neuroleptic Malignant Syndrome
D) Serotonin Syndrome
10. The most common, dose-related side effect of Tricyclic Antidepressants (TCAs) that often
leads to non-adherence is:
A) Weight Gain
B) Sedation
C) Hyponatremia
D) Insomnia
, 11. Which antipsychotic medication carries the highest risk for significant metabolic side
effects like weight gain and diabetes?
A) Ziprasidone (Geodon)
B) Olanzapine (Zyprexa)
C) Lurasidone (Latuda)
D) Haloperidol (Haldol)
12. A patient prescribed Sertraline (Zoloft) should be counseled to avoid which over-the-
counter medication due to the risk of Serotonin Syndrome?
A) Acetaminophen (Tylenol)
B) Ibuprofen (Advil)
C) Pseudoephedrine (Sudafed)
D) Dextromethorphan (Robitussin)
13. The primary goal of using a Mood Stabilizer like Valproate (Depakote) in Bipolar Disorder
is:
A) To cure the underlying condition
B) To provide immediate sedation during mania
C) To reduce the frequency and severity of mood episodes
D) To treat comorbid anxiety
14. Which lab value is most essential to monitor before and during treatment with
Carbamazepine (Tegretol)?
A) Serum Potassium
B) Complete Blood Count (CBC)
C) Lipase
D) International Normalized Ratio (INR)
15. A patient taking Benztropine (Cogentin) is likely being treated for:
A) Depression
B) Extrapyramidal Symptoms (EPS)
C) Hypertension
D) Insomnia
16. Which statement by a patient taking Lamotrigine (Lamictal) indicates a need for
immediate medical attention?
A) "I feel a bit dizzy sometimes."
B) "I have a new rash."
C) "I've had some weird dreams."
D) "My appetite has decreased."