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heat/cold, massage
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1 What is inflammation? 2 Role of basophils/mast cells?
Characteristics of acute Cutaneous stimulation Pain Relief
3 4
inflammation? Method:
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Terms in this set (94)
A physiologic reaction of vascularized tissue to
What is inflammation? injury; protective response to neutralize agents,
remove damaged tissue, and promote healing
, What are the cardinal Redness, heat, swelling, pain, and loss of function
signs of local
inflammation?
- Redness
What are local - Warmth
manifestations of - Pain
inflammation? - Swelling
- Loss of function at site
- Fever
- Leukocytosis (>10,000/mL)
- Fatigue
What are systemic
- Headache
manifestations of
- Malaise
inflammation?
- Anorexia
- increased CRP, increased ESR, increased
fibrinogen
- Rapid onset
Characteristics of acute - Short duration (<2 weeks)
inflammation? - Mainly neutrophils
- Protective/self-limiting
- Slow onset
- Long duration (months-years)
Characteristics of chronic
- Macrophages & lymphocytes dominate
inflammation?
- Fibrosis & granuloma
- Not protective
- Vasodilation
- Increased blood flow
What happens in the
- Increased vascular permeability → redness, heat,
vascular stage?
swelling, pain; mediated by histamine, bradykinin,
prostaglandins
- WBC margination
- Adhesion
What happens in the
- Transmigration
cellular stage?
- Chemotaxis
- Phagocytosis by neutrophils/macrophages