PACOP Module 2 (MC) Questions and
Answers | Latest Version | 2025/2026 |
Correct & Verified
Which process describes the conversion of a drug from dosage form to solution?
a. Distribution
✔✔ b. Dissolution
c. Absorption
d. Elimination
The pH at which a drug is 50% ionized and 50% unionized is known as:
a. Solubility point
✔✔ b. pKa
c. pHmax
d. Ka
Which pharmacokinetic phase is concerned with the movement of drug from site of
administration to systemic circulation?
a. Distribution
1
,b. Metabolism
✔✔ c. Absorption
d. Excretion
Which organ is the primary site of drug metabolism?
a. Kidney
✔✔ b. Liver
c. Lungs
d. Skin
The term "first-pass effect" mainly occurs after:
✔✔ a. Oral administration
b. Intravenous injection
c. Intramuscular injection
d. Sublingual administration
Which transport process requires energy and moves drugs against concentration gradient?
a. Passive diffusion
2
,✔✔ b. Active transport
c. Facilitated diffusion
d. Filtration
Which plasma protein is primarily responsible for binding acidic drugs?
✔✔ a. Albumin
b. Globulin
c. Hemoglobin
d. Fibrinogen
Which pharmacokinetic parameter represents the volume in which a drug appears to be
distributed?
a. Clearance
✔✔ b. Volume of distribution
c. Half-life
d. Bioavailability
The fraction of unchanged drug reaching the systemic circulation is known as:
3
, a. First-pass effect
✔✔ b. Bioavailability
c. Distribution coefficient
d. Clearance
Which organ is the major site of drug excretion?
a. Lungs
✔✔ b. Kidneys
c. Skin
d. Intestine
What does the term “half-life” of a drug mean?
✔✔ a. Time required for plasma concentration to reduce by 50%
b. Time for complete elimination
c. Time for peak plasma concentration
d. Time for absorption to finish
Which order of kinetics shows a constant fraction of drug eliminated per unit time?
4
Answers | Latest Version | 2025/2026 |
Correct & Verified
Which process describes the conversion of a drug from dosage form to solution?
a. Distribution
✔✔ b. Dissolution
c. Absorption
d. Elimination
The pH at which a drug is 50% ionized and 50% unionized is known as:
a. Solubility point
✔✔ b. pKa
c. pHmax
d. Ka
Which pharmacokinetic phase is concerned with the movement of drug from site of
administration to systemic circulation?
a. Distribution
1
,b. Metabolism
✔✔ c. Absorption
d. Excretion
Which organ is the primary site of drug metabolism?
a. Kidney
✔✔ b. Liver
c. Lungs
d. Skin
The term "first-pass effect" mainly occurs after:
✔✔ a. Oral administration
b. Intravenous injection
c. Intramuscular injection
d. Sublingual administration
Which transport process requires energy and moves drugs against concentration gradient?
a. Passive diffusion
2
,✔✔ b. Active transport
c. Facilitated diffusion
d. Filtration
Which plasma protein is primarily responsible for binding acidic drugs?
✔✔ a. Albumin
b. Globulin
c. Hemoglobin
d. Fibrinogen
Which pharmacokinetic parameter represents the volume in which a drug appears to be
distributed?
a. Clearance
✔✔ b. Volume of distribution
c. Half-life
d. Bioavailability
The fraction of unchanged drug reaching the systemic circulation is known as:
3
, a. First-pass effect
✔✔ b. Bioavailability
c. Distribution coefficient
d. Clearance
Which organ is the major site of drug excretion?
a. Lungs
✔✔ b. Kidneys
c. Skin
d. Intestine
What does the term “half-life” of a drug mean?
✔✔ a. Time required for plasma concentration to reduce by 50%
b. Time for complete elimination
c. Time for peak plasma concentration
d. Time for absorption to finish
Which order of kinetics shows a constant fraction of drug eliminated per unit time?
4
