Histology Prelab – Lymphatics Exam With complete solution–
Expert Verified | Latest Questions 2025
Valves to prevent backflow
Smooth muscles in the walls of lymphatic vessels
Squeezing movement of skeletal muscles - What factors drive the lymph transport?
Lymphatic capillary -> Afferent lymphatic vessel -> lymph node -> efferent lymphatic
vessel -> lymphatic trunk -> collecting duct -> subclavian vein - What is the path of
lymph flow?
Lacteals - What are lymphatic capillaries called in the GI tract?
Type of vessel found in CT of all organs that drains interstitial fluid - What are lymphatic
capillaries?
Small blind-ended, thin-walled
No RBCs
Lined with fenestrated endothelium and incomplete BM - What is the histological
appearance of lymphatic capillaries?
ileum - Where is the best place to see lymphatic capillaries?
Intestinal villi (singular = villus) - What are the finger-like projections into the lumen that
contain lacteals in the ileum called?
Appears as vacuolated space in central part of some villi
Surrounded by rich blood fenestrated capillary network and LCT
LCT contains numerous scattered WBC (diffuse lymphatic tissue of MALT) - What is the
histological appearance of a lacteal?
discontinuous - All lymphatic capillaries have a _________________ basement
membrane
Lymphatic capillary - What is the beginning of the efferent collecting lymphatic vessel?
Tissue fluid and fat (chylomicrons) - What is collected into lacteals?
As it enters a lymph node - When do afferent lymphatic vessels become efferent?
The thoracic duct - What is the largest lymphatic vessel/
Yes - Are there valves in afferent lymphatic vessels?
, Appear similar to small veins
Only found in Lymph nodes - Where is the histological appearance of afferent lymphatic
vessels?
Bone marrow and Thymus - What are the primary lymphoid organs?
Starts as liver, then transfers to spleen, then to long bones all prenatally
Transfers to flat bones in adulthood - What is the primary site of hematopoiesis
throughout life?
Reticular tissue and adipose tissue
Numerous discontinuous capillaries with no BM or TJs - What are the histological
features of bone marrow?
Thymic cortex and thymic medulla - What are the regions of the thymus?
Trabeculae - What is the CT septa in the thymus that runs between the lobules called?
Epithelial reticular cells - What cells are unique to the thymus?
Endoderm derived
Involved in thymic maturation/education, stromal support, and contribute to blood-
thymus barrier - What are epithelial reticular cells?
AKA thymic corpuscles
Made up of old epithelial reticular cells
Found in medulla of thymus
Key to thymus identification and thymic medulla - What are Hassall's corpuscles?
Prevents entry of foreign antigen into thymus - What is the blood-thymus barrier?
Thymic cortex and medulla - What is the site of thymocyte (T cell) maturation and
education?
When T cells learn to distinguish between self antigen and recognize MHC I and MHC II
T cells learn self-tolerance and become immunocompetent - What is T cell maturation
and education consist of?
Occurs in thymic cortex
T cells begin to express TAR (specific antigen receptor) and recognize MHC - What is
immunocompetence?
Occurs in thymic medulla
T cells mature and express CD4 or CD8
Become exposed to numerous antigens - What is self-tolerance?
Expert Verified | Latest Questions 2025
Valves to prevent backflow
Smooth muscles in the walls of lymphatic vessels
Squeezing movement of skeletal muscles - What factors drive the lymph transport?
Lymphatic capillary -> Afferent lymphatic vessel -> lymph node -> efferent lymphatic
vessel -> lymphatic trunk -> collecting duct -> subclavian vein - What is the path of
lymph flow?
Lacteals - What are lymphatic capillaries called in the GI tract?
Type of vessel found in CT of all organs that drains interstitial fluid - What are lymphatic
capillaries?
Small blind-ended, thin-walled
No RBCs
Lined with fenestrated endothelium and incomplete BM - What is the histological
appearance of lymphatic capillaries?
ileum - Where is the best place to see lymphatic capillaries?
Intestinal villi (singular = villus) - What are the finger-like projections into the lumen that
contain lacteals in the ileum called?
Appears as vacuolated space in central part of some villi
Surrounded by rich blood fenestrated capillary network and LCT
LCT contains numerous scattered WBC (diffuse lymphatic tissue of MALT) - What is the
histological appearance of a lacteal?
discontinuous - All lymphatic capillaries have a _________________ basement
membrane
Lymphatic capillary - What is the beginning of the efferent collecting lymphatic vessel?
Tissue fluid and fat (chylomicrons) - What is collected into lacteals?
As it enters a lymph node - When do afferent lymphatic vessels become efferent?
The thoracic duct - What is the largest lymphatic vessel/
Yes - Are there valves in afferent lymphatic vessels?
, Appear similar to small veins
Only found in Lymph nodes - Where is the histological appearance of afferent lymphatic
vessels?
Bone marrow and Thymus - What are the primary lymphoid organs?
Starts as liver, then transfers to spleen, then to long bones all prenatally
Transfers to flat bones in adulthood - What is the primary site of hematopoiesis
throughout life?
Reticular tissue and adipose tissue
Numerous discontinuous capillaries with no BM or TJs - What are the histological
features of bone marrow?
Thymic cortex and thymic medulla - What are the regions of the thymus?
Trabeculae - What is the CT septa in the thymus that runs between the lobules called?
Epithelial reticular cells - What cells are unique to the thymus?
Endoderm derived
Involved in thymic maturation/education, stromal support, and contribute to blood-
thymus barrier - What are epithelial reticular cells?
AKA thymic corpuscles
Made up of old epithelial reticular cells
Found in medulla of thymus
Key to thymus identification and thymic medulla - What are Hassall's corpuscles?
Prevents entry of foreign antigen into thymus - What is the blood-thymus barrier?
Thymic cortex and medulla - What is the site of thymocyte (T cell) maturation and
education?
When T cells learn to distinguish between self antigen and recognize MHC I and MHC II
T cells learn self-tolerance and become immunocompetent - What is T cell maturation
and education consist of?
Occurs in thymic cortex
T cells begin to express TAR (specific antigen receptor) and recognize MHC - What is
immunocompetence?
Occurs in thymic medulla
T cells mature and express CD4 or CD8
Become exposed to numerous antigens - What is self-tolerance?
