CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE PRACTITIONER
BOARD EXAM PREP 2025/2026
COMPLETE 450 QUESTIONS AND
CORRECT ANSWERS WITH
RATIONALES |ALREADY GRADED
A+||BRAND NEW!!!
In addition to a developmental evaluation, which baseline studies should be included for an infant
diagnosed with 22q11 deletion syndrome?
echocardiogram, thyroid function, and renal ultrasound
calcium levels, abdominal ultrasound, and immunologic screening
echocardiogram, renal ultrasound, and immunologic screening
thyroid function, calcium levels, and abdominal ultrasound
echocardiogram, renal ultrasound, and immunologic screening
The 22q11 deletion syndrome, also known as DiGeorge syndrome or thymic hypoplasia, is one of the
most common genetic syndromes affecting 1 in 4000 infants. The most prevalent clinical findings
include congenital heart defects, usually tetralogy of Fallot or truncal defects, characteristic facial
features, especially palatal abnormalities, immune deficiencies, hypocalcemia, speech and
developmental delays, feeding problems, and renal anomalies. Development and speech are major
concerns in children with 22q11 deletion, so early intervention is extremely important. Baseline
screening should include echocardiography, renal ultrasound, and immunologic evaluation, including
T and B cell flow cytometry and quantitative IG and calcium levels. Abdominal ultrasound is not
indicated and hypocalcemia is the result of hypoparathyroidism, not hypothyroidism, so thyroid
levels are not indicated initially.
A+ TEST BANK 1
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
While awaiting culture results, which of the following is the BEST empiric treatment for a febrile child
with urine positive for nitrites and leukocytes in a geographical area with highly resistant E. coli?
amoxicillin
cefixime
nitrofurantoin
TMP/SMX
cefixime
Early therapy for children with urinary tract infections (UTIs) is considered optimal for reducing
illness severity, and the likelihood of long-term renal injury. Children with a urinalysis or microscopic
urine evaluation suggesting UTI should be given empiric antibiotic therapy until culture results are
available. Resistance to amoxicillin is approaching 35% and to TMP/SMX is approaching 20%. Cefixime
is the recommended therapy unless resistance has been shown in the local community.
Nitrofurantoin is not recommended for use in children with febrile evidence of UTI because it does
not concentrate well in the kidneys.
When counseling parents whose children have had food-induced anaphylaxis, which teaching point is
the MOST important?
Children with asthma tend to have more severe food-induced allergic reactions.
Exercise can be a co-factor in food induced anaphylaxis.
The severity of previous reactions cannot predict the severity of future reactions.
Timely administration of epinephrine is the standard of care.
- Timely administration of epinephrine is the standard of care.
A+ TEST BANK 2
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
Parents should be aware of the fact that food-induced allergic reactions can occur during or soon
after exercise, and food allergies and asthma often co-exist. Children with asthma tend to have more
severe food-induced reactions and the intensity of previous allergic reactions to foods cannot predict
the severity of subsequent reactions. Ultimately, in a child with a history of food-induced
anaphylaxis, it is MOST important that parents understand that only epinephrine can stop a food-
induced allergic reaction and it should be administered immediately when symptoms occur.
Reinforcing that epinephrine should always be carried and immediately available is another
important teaching point.
Of the following, the MOST effective method to prevent childhood gun injuries and death is
parents and caregivers eliminating children's access to guns.
educating children with the Eddie the Eagle program.
educating children with the STAR Program
parents and caregivers making children aware of locked guns in the home.
parents and caregivers eliminating children's access to guns.
It is widely believed that teaching gun safety to young children is effective in keeping them from
handling guns when found, thus decreasing childhood gun deaths and injury. The most advertised
program is the National Rifle Association's Eddie Eagle Gun Safety Program that teaches children
when they find a gun to stop, do not touch, leave the area, and tell an adult. The Straight Talk About
Risks (STAR) Program developed by the Center to Prevent Handgun Violence emphasizes learning,
practicing gun safety skills, role playing, and self-reflection using common coping mechanisms for
anger and fear. In a controlled study looking at actual behavior in matched groups, half who had a
gun safety program based on the STAR program and half who had no gun safety instruction, no
significant differences were found in the percentage of children who handled the gun, left the area,
and contacted an adult. No controlled study has been done on the effectiveness of the Eddie Eagle
Gun Safety Program. The American Academy of Pediatrics maintains that the most reliable and
effective means of preventing gun deaths and injury is the removal of guns from children's homes
and communities.
According to the National Asthma Education and Prevention Program (NAEPP) Expert Panel 3
Update, potential long-term adverse effects of chronic inhaled corticosteroids use in children
A+ TEST BANK 3
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
includes
decreased bone mineral density.
hypothalamic-pituitary-axis (HPA) suppression.
vertical growth delay in the first year of treatment.
ocular toxicity.
vertical growth delay in the first year of treatment.
There is strong evidence from clinical trials that followed children for up to 6 years indicating that the
use of long-term daily inhaled corticosteroids is safe in children. There is no evidence of decreased
bone mineral density, HPA suppression or ocular toxicity (cataracts or glaucoma). There is a potential
for slight growth delay (1 cm in height in the first year), but this is not sustained in subsequent years
of treatment, is not progressive, and may be reversible.
Which test is the MOST sensitive EARLY indicator for musculoskeletal inflammatory disorders?
complete blood count with differential (CBC)
C-reactive protein (CRP)
erythrocyte sedimentation rate (ESR)
anti-nuclear antibodies (ANA)
C-reactive protein (CRP)
The C-reactive protein (CRP) is an acute phase reactant serum protein which rises rapidly under an
inflammatory stimulus. The ESR also documents inflammation and assists in following the course of
some chronic rheumatic disorders. The ESR can be falsely low in some illnesses, and the results are
affected by prolonged storage of the blood or tilting of the calibrated tube. The CRP has an
advantage over the ESR in that it may be performed on freeze-dried specimens, and is most sensitive
for early infections and inflammatory processes. The CBC with differential may indicate infection, but
is not always elevated in the presence of inflammation. ANA is often present in individuals with
A+ TEST BANK 4
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE PRACTITIONER
BOARD EXAM PREP 2025/2026
COMPLETE 450 QUESTIONS AND
CORRECT ANSWERS WITH
RATIONALES |ALREADY GRADED
A+||BRAND NEW!!!
In addition to a developmental evaluation, which baseline studies should be included for an infant
diagnosed with 22q11 deletion syndrome?
echocardiogram, thyroid function, and renal ultrasound
calcium levels, abdominal ultrasound, and immunologic screening
echocardiogram, renal ultrasound, and immunologic screening
thyroid function, calcium levels, and abdominal ultrasound
echocardiogram, renal ultrasound, and immunologic screening
The 22q11 deletion syndrome, also known as DiGeorge syndrome or thymic hypoplasia, is one of the
most common genetic syndromes affecting 1 in 4000 infants. The most prevalent clinical findings
include congenital heart defects, usually tetralogy of Fallot or truncal defects, characteristic facial
features, especially palatal abnormalities, immune deficiencies, hypocalcemia, speech and
developmental delays, feeding problems, and renal anomalies. Development and speech are major
concerns in children with 22q11 deletion, so early intervention is extremely important. Baseline
screening should include echocardiography, renal ultrasound, and immunologic evaluation, including
T and B cell flow cytometry and quantitative IG and calcium levels. Abdominal ultrasound is not
indicated and hypocalcemia is the result of hypoparathyroidism, not hypothyroidism, so thyroid
levels are not indicated initially.
A+ TEST BANK 1
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
While awaiting culture results, which of the following is the BEST empiric treatment for a febrile child
with urine positive for nitrites and leukocytes in a geographical area with highly resistant E. coli?
amoxicillin
cefixime
nitrofurantoin
TMP/SMX
cefixime
Early therapy for children with urinary tract infections (UTIs) is considered optimal for reducing
illness severity, and the likelihood of long-term renal injury. Children with a urinalysis or microscopic
urine evaluation suggesting UTI should be given empiric antibiotic therapy until culture results are
available. Resistance to amoxicillin is approaching 35% and to TMP/SMX is approaching 20%. Cefixime
is the recommended therapy unless resistance has been shown in the local community.
Nitrofurantoin is not recommended for use in children with febrile evidence of UTI because it does
not concentrate well in the kidneys.
When counseling parents whose children have had food-induced anaphylaxis, which teaching point is
the MOST important?
Children with asthma tend to have more severe food-induced allergic reactions.
Exercise can be a co-factor in food induced anaphylaxis.
The severity of previous reactions cannot predict the severity of future reactions.
Timely administration of epinephrine is the standard of care.
- Timely administration of epinephrine is the standard of care.
A+ TEST BANK 2
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
Parents should be aware of the fact that food-induced allergic reactions can occur during or soon
after exercise, and food allergies and asthma often co-exist. Children with asthma tend to have more
severe food-induced reactions and the intensity of previous allergic reactions to foods cannot predict
the severity of subsequent reactions. Ultimately, in a child with a history of food-induced
anaphylaxis, it is MOST important that parents understand that only epinephrine can stop a food-
induced allergic reaction and it should be administered immediately when symptoms occur.
Reinforcing that epinephrine should always be carried and immediately available is another
important teaching point.
Of the following, the MOST effective method to prevent childhood gun injuries and death is
parents and caregivers eliminating children's access to guns.
educating children with the Eddie the Eagle program.
educating children with the STAR Program
parents and caregivers making children aware of locked guns in the home.
parents and caregivers eliminating children's access to guns.
It is widely believed that teaching gun safety to young children is effective in keeping them from
handling guns when found, thus decreasing childhood gun deaths and injury. The most advertised
program is the National Rifle Association's Eddie Eagle Gun Safety Program that teaches children
when they find a gun to stop, do not touch, leave the area, and tell an adult. The Straight Talk About
Risks (STAR) Program developed by the Center to Prevent Handgun Violence emphasizes learning,
practicing gun safety skills, role playing, and self-reflection using common coping mechanisms for
anger and fear. In a controlled study looking at actual behavior in matched groups, half who had a
gun safety program based on the STAR program and half who had no gun safety instruction, no
significant differences were found in the percentage of children who handled the gun, left the area,
and contacted an adult. No controlled study has been done on the effectiveness of the Eddie Eagle
Gun Safety Program. The American Academy of Pediatrics maintains that the most reliable and
effective means of preventing gun deaths and injury is the removal of guns from children's homes
and communities.
According to the National Asthma Education and Prevention Program (NAEPP) Expert Panel 3
Update, potential long-term adverse effects of chronic inhaled corticosteroids use in children
A+ TEST BANK 3
, CPNP-PC CERTIFIED PEDIATRIC
PRIMARY CARE NURSE
PRACTITIONER BOARD EXAM
includes
decreased bone mineral density.
hypothalamic-pituitary-axis (HPA) suppression.
vertical growth delay in the first year of treatment.
ocular toxicity.
vertical growth delay in the first year of treatment.
There is strong evidence from clinical trials that followed children for up to 6 years indicating that the
use of long-term daily inhaled corticosteroids is safe in children. There is no evidence of decreased
bone mineral density, HPA suppression or ocular toxicity (cataracts or glaucoma). There is a potential
for slight growth delay (1 cm in height in the first year), but this is not sustained in subsequent years
of treatment, is not progressive, and may be reversible.
Which test is the MOST sensitive EARLY indicator for musculoskeletal inflammatory disorders?
complete blood count with differential (CBC)
C-reactive protein (CRP)
erythrocyte sedimentation rate (ESR)
anti-nuclear antibodies (ANA)
C-reactive protein (CRP)
The C-reactive protein (CRP) is an acute phase reactant serum protein which rises rapidly under an
inflammatory stimulus. The ESR also documents inflammation and assists in following the course of
some chronic rheumatic disorders. The ESR can be falsely low in some illnesses, and the results are
affected by prolonged storage of the blood or tilting of the calibrated tube. The CRP has an
advantage over the ESR in that it may be performed on freeze-dried specimens, and is most sensitive
for early infections and inflammatory processes. The CBC with differential may indicate infection, but
is not always elevated in the presence of inflammation. ANA is often present in individuals with
A+ TEST BANK 4
