NRNP 6566 Advanced Care
of Adults in Acute Settings
I – Week 6 Knowledge
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Answers (2025/2026)
Instructions
Carefully review each question.
Identify the key clinical issue being asked.
Select the best answer and confirm with the rationale
provided.
Secti
Use this quiz as a practice for Week 6 material mastery.
, 2
Question 1
For the following ABG results (pH 7.08, pCO2 54 mm Hg, pO2 54 mm Hg, HCO3
15 mEq/L), identify the acid-base disorder, compensation, and level of hypoxemia.
A. Acute respiratory acidosis with metabolic acidosis and severe hypoxemia B.
Acute respiratory and metabolic acidosis with moderate hypoxemia C. Chronic
respiratory alkalosis with no compensation and mild hypoxemia D. Metabolic
alkalosis with respiratory compensation and no hypoxemia
Answer: B. Acute respiratory and metabolic acidosis with moderate
hypoxemia Rationale: The pH <7.35 indicates acidosis. Elevated pCO2 (>45 mm
Hg) confirms respiratory acidosis (acute as pCO2 is not chronically compensated).
Low HCO3 (<22 mEq/L) indicates metabolic acidosis. pO2 54 mm Hg (normal 80-
100) is moderate hypoxemia (severe <50). This mixed disorder requires immediate
intervention for ventilation and metabolic correction in acute settings.
Question 2
A 66-year-old male with COPD presents with worsening dyspnea, pH 7.32, pCO2
55 mm Hg, pO2 65 mm Hg, HCO3 28 mEq/L. What is the primary acid-base
disturbance? A. Uncompensated respiratory acidosis B. Partially compensated
respiratory acidosis C. Fully compensated respiratory acidosis D. Metabolic
alkalosis
Answer: B. Partially compensated respiratory acidosis Rationale: In COPD,
chronic CO2 retention causes respiratory acidosis (pH <7.35, pCO2 >45). Elevated
HCO3 (28 mEq/L) shows renal compensation (kidneys retain HCO3), but pH is
not normalized (7.35-7.45), indicating partial compensation. pO2 65 mm Hg
suggests hypoxemia needing oxygen titration to avoid suppressing drive.
Question 3