Science Biology Pathology
ASCP Certification UPDATED ACTUAL Questions and
CORRECT Answers
Terms in this set (537)
loss of DNA --> nuclear pallor = karyolysis
nuclear shrinkage and increased pyknosis
basophilia =
fragmented, pyknotic nucleus = karyorrhexis
architecture is preserved in what coagulative
necrosis?
bacteria/fungus/inflammation/e liquifactive
nzymes are part of what
necrosis?
WBC recruitment steps margination/rolling --> adhesion --> transmigration --> migration
WBC rolling via _____ selectins
WBC adhesion via ____ integrins
endothelial injury + stasis/turbulent blood flow +
Virchow's triad of thrombosis
hypercoagulability
most abundant collagen type I
collagen in scar tissue, tendons, type I
ligaments
collagen in cartilage type II
reticular collagen type type III
BM collagen type type IV
what does vWF do? helps platelets adhere to endothelium
FBN1 mutation = what disorder Marfan syndrome
fibrillin mutation = what disorder Marfan syndrome
mutated collagen = what Ehlers-Danlos
disorder
https://quizlet.com/240443007/ascp-certification-flash-cards/ 1/5
, musty urine odor = what PKU
disorder
mutated beta-hexosaminidase A Tay Sachs
= what disorder
increased gangliosides = what Tay Sachs
disorder
mutated Neimann Pick
sphingomyelinase/increased
sphingomyelin = what disorder
mutated Gaucher
glucocerebrosidase/increased
glucocerebroside = what
disorder
trisomy 13 aka Patau
Patau = trisomy 13
trisomy 18 aka Edwards'
Edwards' = trisomy 18
3 viable trisomies 13, 18, 21
maternal imprinting silencing of maternal allele
paternal imprinting silencing of paternal allele
#1 infant tumor hemangioma
#1 extracranial child tumor neuroblastoma
PDK1 mutation = what disorder adult PKD
polycystin-1 defect = what adult PKD
disorder
PKHD1 mutation = what disorder childhood PKD
fibrocystin defect = what childhood PKD
disorder
MHS2/MLH1 mutation = what HNPCC/Lynch
disorder
most common newborn viral CMV
infection
Hyaline membrane disease defective surfactant --> solid, airless lungs in infant
macrosomia/large tongue/large kidneys
Beckwith-Wiedemann kidney, pancreas, adrenal issues
earlobe creases
type I HS immediate, allergy
type II HS Ab-mediated
HS type of myasthenia gravis II
HS type of Grave's II
HS type of pernicious/hemolytic II
anemia
HS type of Goodpasture's II
https://quizlet.com/240443007/ascp-certification-flash-cards/ 2/5
ASCP Certification UPDATED ACTUAL Questions and
CORRECT Answers
Terms in this set (537)
loss of DNA --> nuclear pallor = karyolysis
nuclear shrinkage and increased pyknosis
basophilia =
fragmented, pyknotic nucleus = karyorrhexis
architecture is preserved in what coagulative
necrosis?
bacteria/fungus/inflammation/e liquifactive
nzymes are part of what
necrosis?
WBC recruitment steps margination/rolling --> adhesion --> transmigration --> migration
WBC rolling via _____ selectins
WBC adhesion via ____ integrins
endothelial injury + stasis/turbulent blood flow +
Virchow's triad of thrombosis
hypercoagulability
most abundant collagen type I
collagen in scar tissue, tendons, type I
ligaments
collagen in cartilage type II
reticular collagen type type III
BM collagen type type IV
what does vWF do? helps platelets adhere to endothelium
FBN1 mutation = what disorder Marfan syndrome
fibrillin mutation = what disorder Marfan syndrome
mutated collagen = what Ehlers-Danlos
disorder
https://quizlet.com/240443007/ascp-certification-flash-cards/ 1/5
, musty urine odor = what PKU
disorder
mutated beta-hexosaminidase A Tay Sachs
= what disorder
increased gangliosides = what Tay Sachs
disorder
mutated Neimann Pick
sphingomyelinase/increased
sphingomyelin = what disorder
mutated Gaucher
glucocerebrosidase/increased
glucocerebroside = what
disorder
trisomy 13 aka Patau
Patau = trisomy 13
trisomy 18 aka Edwards'
Edwards' = trisomy 18
3 viable trisomies 13, 18, 21
maternal imprinting silencing of maternal allele
paternal imprinting silencing of paternal allele
#1 infant tumor hemangioma
#1 extracranial child tumor neuroblastoma
PDK1 mutation = what disorder adult PKD
polycystin-1 defect = what adult PKD
disorder
PKHD1 mutation = what disorder childhood PKD
fibrocystin defect = what childhood PKD
disorder
MHS2/MLH1 mutation = what HNPCC/Lynch
disorder
most common newborn viral CMV
infection
Hyaline membrane disease defective surfactant --> solid, airless lungs in infant
macrosomia/large tongue/large kidneys
Beckwith-Wiedemann kidney, pancreas, adrenal issues
earlobe creases
type I HS immediate, allergy
type II HS Ab-mediated
HS type of myasthenia gravis II
HS type of Grave's II
HS type of pernicious/hemolytic II
anemia
HS type of Goodpasture's II
https://quizlet.com/240443007/ascp-certification-flash-cards/ 2/5
