Answers
1. MC inherited thrombophilia Factor 5 Leiden
2. What happens in Factor 5 Leiden muta- Hyper coagulable state
tion Form LOTS of clots
3. What are some Physical Exam signs of Development of venous thromboembolsm
of Factor 5 Leiden? DVT
Pulm Embolism
MIscarriages
4. Diagnosis for Factor 5 Leiden Check activated protein C
Genetic testing -Autosomal dominant
Fam Hx
Unexplained clots
5. Tx for Factor 5 Leinden No management indicated if they no longer have
active clot
Begin anticoagulant if they do
6. Neonatal purpura Protein C/S Deficiency
7. Immune Thrombocytopenic Purpura bleeding
(ITP) signs and symptoms -petechiae
-ecchymoses
Buising
Gingival bleeding
Epistaxis
Heavy menstral periods
8. What causes Immune Thrombocy- Autoimmune disorder that destroys platelets
topenic Purpura? Can be idiopathic, brought on by viral infection
, or Medications