1. A 55-year-old woman presents with a gradual onset of A.
a cough, dyspnea, and red eyes for 11 months. She has Granulomatosis with
been treated multiple times for otitis media and sinusi- polyangiitis
tis. She also reports ankle pain that has migrated to
her knee. Physical exam reveals saddle nose deformity,
nasal septum crusting, anterior uveitis, and otitis me-
dia. Laboratory tests reveal a positive antineutrophil
cytoplasmic antibody directed towards proteinase-3.
Anticyclic citrullinated peptide antibody and rheuma-
toid factor are absent. Tissue biopsy shows granulo-
matous inflammation and geographic necrosis. Which
of the following is the most likely diagnosis?
A.
Granulomatosis with polyangiitis
B.
Microscopic polyangiitis
C.
Refractory sinusitis
D.
Rheumatoid arthritis
2. Which of the following increases the risk of osteoporo- D.
sis in postmenopausal individuals? Smoking cigarettes
A.
Calcium and vitamin D supplementation
B.
Minimal alcohol intake
C.
, Regular physical activity
D.
Smoking cigarettes
3. A 62-year-old woman presents to the office with scalp D.
tenderness on the left side of her head, double vision, Prednisone
and pain with chewing that started about two days ago
and has gotten worse. Physical exam reveals a tender
and enlarged left temporal artery, and you suspect
giant cell arteritis. Which of the following is the most
appropriate treatment for this condition?
A.
Aspirin
B.
Methotrexate
C.
Nonsteroidal anti-inflammatories
D.
Prednisone
4. Which of the following is considered a first-line A.
pharmacologic therapy for osteoporosis in post- Alendronate
menopausal patients?
A.
Alendronate
B.
Denosumab
, C.
Raloxifene
D.
Teriparatide
5. Which of the following diagnostic findings is sugges- C.
tive of pseudogout? Synovial fluid analysis
A. showing crystals with a
High serum uric acid rhomboid shape
B.
Negatively birefringent crystals
C.
Synovial fluid analysis showing crystals with a rhom-
boid shape
D.
Synovial fluid analysis showing needle-like crystals
6. A 40-year-old woman presents to the clinic with pain B.
and morning stiffness in her fingers and toes. She Psoriatic arthritis
describes the morning stiffness as lasting more than
30 minutes but says it improves throughout the day.
On physical examination, you note a "sausage appear-
ance". You also note onycholysis and nail pitting. There
is an erythematous, thick plaque with silvery scale not-
ed around her umbilicus. Laboratory results reveal an
elevated erythrocyte sedimentation rate and uric acid
levels, however, rheumatoid factor and anti-cyclic cit-
rullinated peptide antibodies are absent. The synovial
fluid examination does not show any monosodium