Comprehensive Test Bank for Marieb Human Anatomy &
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter/Section: Chapter 1, Section 1.1
An Overview of Anatomy & Physiology
1. Subtopic: Complementarity of structure & function
Cognitive Level: Recall
Difficulty: Easy
Stem (≤70 words): Which statement best illustrates the
principle “form determines function”?
A. Cells communicate by gap junctions.
B. Molars have flat surfaces for grinding food.
C. Proteins catalyze biochemical reactions.
D. Neurons maintain resting membrane potentials.
Correct Answer: B
Rationale (correct — 3–4 sentences): Marieb emphasizes
that anatomical structures are shaped to perform specific
functions; the flat surfaces of molars are adapted for
grinding food, a clear example of structure enabling
function. This explicit example appears in the chapter’s
discussion of complementarity (Fig. 1.1, pp.32–33). The
statement links a visible structural feature (molars) to its
mechanical role in digestion. Pearson
Incorrect options:
A. True about cell communication but is a mechanism, not
a simple form→function example.
, C. True about enzymes (physiology) but less direct as a
macroscopic form→function illustration.
D. True physiology fact but concerns membrane physiology
rather than gross structural adaptation.
Teaching point: Visible anatomy (shape of a structure)
usually predicts its mechanical role.
2. ID: A&P002
Chapter/Section/Page: Ch.1 — 1.2 The body’s organization
ranges from atoms to the entire organism; Fig. 1.2; p.34–
35. Pearson
Subtopic: Levels of structural organization
Cognitive Level: Recall
Difficulty: Easy
Stem: Which sequence lists levels of organization from
simplest to most complex?
A. Tissue → Cell → Organ → Organ system
B. Atom → Molecule → Cell → Tissue
C. Organ → Tissue → Cell → Organism
D. Molecule → Atom → Organ → Cell
Correct Answer: B
Rationale (correct): Marieb defines the structural
hierarchy: chemical (atoms → molecules), cellular, tissue,
organ, organ system, organism. Sequence B correctly
orders chemical → cellular → tissue levels, matching Figure
1.2 and text (pp.34–35). Understanding this hierarchy is
, foundational for linking molecular events to whole-body
function. Pearson
Incorrect options:
A. Incorrect order — tissue cannot precede cell.
C. Incorrect descending order (organ before tissue/cell).
D. Molecule → Atom is reversed; atoms form molecules.
Teaching point: Memorize the proper hierarchical order:
atoms → molecules → cells → tissues → organs → systems
→ organism.
3. ID: A&P003
Chapter/Section/Page: Ch.1 — 1.2 Organ systems
overview; Fig. 1.4; pp.36–37. Pearson
Subtopic: Organ systems and major functions
Cognitive Level: Recall/Application
Difficulty: Medium
Stem: A patient with impaired gas exchange most directly
implicates which organ system?
A. Digestive
B. Urinary
C. Respiratory
D. Lymphatic
Correct Answer: C
Rationale (correct): Marieb’s organ systems table lists the
respiratory system as responsible for keeping blood
supplied with oxygen and eliminating carbon dioxide (Fig.
, 1.4, pp.36–37). Impaired gas exchange is therefore chiefly
a respiratory problem, though other systems may be
secondarily affected. Recognizing primary system functions
helps target assessment and interventions. Pearson
Incorrect options:
A. Digestive handles nutrient breakdown/absorption, not
gas exchange.
B. Urinary manages wastes and fluid/electrolyte balance,
not primary gas exchange.
D. Lymphatic returns fluid and participates in immunity;
not the main gas exchanger.
Teaching point: Match key clinical problems to the organ
system with the primary related function.
4. ID: A&P004
Chapter/Section/Page: Ch.1 — 1.3 What are the
requirements for life?; pp.35–36. Pearson
Subtopic: Necessary life functions — Maintaining
boundaries
Cognitive Level: Application
Difficulty: Medium
Stem: A burn patient’s primary risk related to loss of the
integumentary boundary is:
A. Respiratory alkalosis
B. Infection and fluid loss
C. Decreased reproductive capacity
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter/Section: Chapter 1, Section 1.1
An Overview of Anatomy & Physiology
1. Subtopic: Complementarity of structure & function
Cognitive Level: Recall
Difficulty: Easy
Stem (≤70 words): Which statement best illustrates the
principle “form determines function”?
A. Cells communicate by gap junctions.
B. Molars have flat surfaces for grinding food.
C. Proteins catalyze biochemical reactions.
D. Neurons maintain resting membrane potentials.
Correct Answer: B
Rationale (correct — 3–4 sentences): Marieb emphasizes
that anatomical structures are shaped to perform specific
functions; the flat surfaces of molars are adapted for
grinding food, a clear example of structure enabling
function. This explicit example appears in the chapter’s
discussion of complementarity (Fig. 1.1, pp.32–33). The
statement links a visible structural feature (molars) to its
mechanical role in digestion. Pearson
Incorrect options:
A. True about cell communication but is a mechanism, not
a simple form→function example.
, C. True about enzymes (physiology) but less direct as a
macroscopic form→function illustration.
D. True physiology fact but concerns membrane physiology
rather than gross structural adaptation.
Teaching point: Visible anatomy (shape of a structure)
usually predicts its mechanical role.
2. ID: A&P002
Chapter/Section/Page: Ch.1 — 1.2 The body’s organization
ranges from atoms to the entire organism; Fig. 1.2; p.34–
35. Pearson
Subtopic: Levels of structural organization
Cognitive Level: Recall
Difficulty: Easy
Stem: Which sequence lists levels of organization from
simplest to most complex?
A. Tissue → Cell → Organ → Organ system
B. Atom → Molecule → Cell → Tissue
C. Organ → Tissue → Cell → Organism
D. Molecule → Atom → Organ → Cell
Correct Answer: B
Rationale (correct): Marieb defines the structural
hierarchy: chemical (atoms → molecules), cellular, tissue,
organ, organ system, organism. Sequence B correctly
orders chemical → cellular → tissue levels, matching Figure
1.2 and text (pp.34–35). Understanding this hierarchy is
, foundational for linking molecular events to whole-body
function. Pearson
Incorrect options:
A. Incorrect order — tissue cannot precede cell.
C. Incorrect descending order (organ before tissue/cell).
D. Molecule → Atom is reversed; atoms form molecules.
Teaching point: Memorize the proper hierarchical order:
atoms → molecules → cells → tissues → organs → systems
→ organism.
3. ID: A&P003
Chapter/Section/Page: Ch.1 — 1.2 Organ systems
overview; Fig. 1.4; pp.36–37. Pearson
Subtopic: Organ systems and major functions
Cognitive Level: Recall/Application
Difficulty: Medium
Stem: A patient with impaired gas exchange most directly
implicates which organ system?
A. Digestive
B. Urinary
C. Respiratory
D. Lymphatic
Correct Answer: C
Rationale (correct): Marieb’s organ systems table lists the
respiratory system as responsible for keeping blood
supplied with oxygen and eliminating carbon dioxide (Fig.
, 1.4, pp.36–37). Impaired gas exchange is therefore chiefly
a respiratory problem, though other systems may be
secondarily affected. Recognizing primary system functions
helps target assessment and interventions. Pearson
Incorrect options:
A. Digestive handles nutrient breakdown/absorption, not
gas exchange.
B. Urinary manages wastes and fluid/electrolyte balance,
not primary gas exchange.
D. Lymphatic returns fluid and participates in immunity;
not the main gas exchanger.
Teaching point: Match key clinical problems to the organ
system with the primary related function.
4. ID: A&P004
Chapter/Section/Page: Ch.1 — 1.3 What are the
requirements for life?; pp.35–36. Pearson
Subtopic: Necessary life functions — Maintaining
boundaries
Cognitive Level: Application
Difficulty: Medium
Stem: A burn patient’s primary risk related to loss of the
integumentary boundary is:
A. Respiratory alkalosis
B. Infection and fluid loss
C. Decreased reproductive capacity
