2025/2026 Premium Study Guide
Full-Length Mock Exam • Answer Key & Rationales • High-Yield Cheat
Sheets
Exam Instructions
This is a full-length ATI Comprehensive Predictor Mock Exam designed to simulate the real
testing experience. The exam includes 150 mixed-format questions covering fundamentals,
pharmacology, medical-surgical, maternity, pediatrics, mental health, and leadership. Each
question is followed by the correct answer and a detailed rationale.
Time limit: 3 hours
Passing benchmark: 90%
Answer carefully and review rationales to maximize learning
,Table of Contents
1. Exam Questions (Sample)
2. Answer Key with Rationales
3. High-Yield Cheat Sheets
,Q1. A nurse is caring for a client receiving IV furosemide. Which finding requires
immediate intervention?
A. Serum potassium 2.8 mEq/L
B. Blood pressure 138/82 mmHg
C. Heart rate 88/min
D. Serum sodium 138 mEq/L
✅ Answer: A
💡 Rationale: Potassium 2.8 mEq/L is dangerously low, risking ventricular
dysrhythmias. Immediate action is required.
Q2. A client with COPD is receiving oxygen via nasal cannula at 6 L/min. Which action
should the nurse take?
A. Continue therapy as prescribed
B. Lower to 2 L/min
C. Switch to non-rebreather mask
D. Encourage deep breathing exercises
✅ Answer: B
💡 Rationale: COPD clients should receive low-flow oxygen (1–3 L/min) to prevent
suppression of their hypoxic respiratory drive.
Q3. A nurse is teaching a client about warfarin therapy. Which statement indicates
correct understanding?
A. “I will eat more green leafy vegetables.”
B. “I will report any unusual bleeding.”
C. “I can take aspirin for headaches.”
D. “I do not need regular lab tests.”
✅ Answer: B
💡 Rationale: Warfarin increases bleeding risk. Clients must report unusual bleeding
immediately. Aspirin increases bleeding risk and should be avoided.
Q4. Which client should the nurse assess first?
A. Post-op client reporting pain 6/10
, B. Client with new onset confusion
C. Client scheduled for discharge
D. Client requesting PRN medication
✅ Answer: B
💡 Rationale: New confusion could indicate hypoxia, infection, or neurological decline,
making this client the highest priority.
Q5. A nurse is caring for a postpartum client with a boggy uterus. Which action is
priority?
A. Administer oxytocin
B. Massage the fundus
C. Encourage ambulation
D. Start IV fluids
✅ Answer: B
💡 Rationale: Uterine atony is the leading cause of postpartum hemorrhage. Massaging
the fundus is the first nursing action.
Q6. A client on heparin infusion develops hematuria. Which medication should the nurse
anticipate administering?
A. Vitamin K
B. Protamine sulfate
C. Atropine
D. Naloxone
✅ Answer: B
💡 Rationale: Protamine sulfate is the antidote for heparin toxicity. Vitamin K is for
warfarin overdose.
Q7. Which action is appropriate when administering ear drops to a 2-year-old child?
A. Pull pinna up and back
B. Pull pinna down and back
C. Instill drops onto tympanic membrane
D. Warm drops in microwave