NUR 502 Exam (Actual Exam 2026) | Advanced
Pathophysiology Exam | All Questions and Correct
Answers (Verified Answers) | Just Released
The normal platelet count is - (ANSWER)150-300,000
Platelets are formed by - (ANSWER)Megakaryocytes in the bone marrow
When a vessel is damaged, what begins the clotting process? -
(ANSWER)Adherence of platelets to the vessel wall
In what 3 conditions will you see an increase in platelet count? - (ANSWER)1.)
Active bleeding, 2.) Postsplenectomy, 3.) Myeloproliferative diseases
In what conditions is the platelet count decreased? - (ANSWER)DIC, TTP, HIT, ITP,
AND drugs; EDTA-DEPENDENT agglutination, infection, ETOH
The intrinsic pathway and extrinsic pathway are part of what? - (ANSWER)The
coagulation cascade
What is a normal PT time? - (ANSWER)11-14 Sec
, 2
What does the PT/INR evaluate? - (ANSWER)The extrinsic and common pathway.
What is the PT/INR most sensitive to? - (ANSWER)the vitamin K-dependent
clotting factors 2, 7, 9, and 10
What do we use the PT/INR for? - (ANSWER)To monitor Coumadin therapy
What replaces the PT for better standardization in thromboplastin reagents
worldwide? - (ANSWER)The INR
In which conditions would you expect to see an elevation of the INR? -
(ANSWER)Liver disease; Coumadin therapy; DIC; Hereditary factor deficiencies in
10, 5, 7, and 1; massive blood transfusions
What is the normal partial thromboplastin time? - (ANSWER)26-34 Sec
What does the PTT evaluate? - (ANSWER)The intrinsic and common pathway
, 3
What drug therapy is the PTT used to monitor? - (ANSWER)Heparin therapy
Which pts can a PTT NOT be used in to monitor heparin? - (ANSWER)Pts with
lupus anticoagulant
What must be used to monitor heparin therapy in a pt with lupus anticoagulant? -
(ANSWER)Factor 10 A levels
True or false, Heparin contamination from lines can give falsely elevated PTT. -
(ANSWER)True
In which conditions would you see an increased PTT? - (ANSWER)Deficiency in
specific coagulation factors in the intrinsic pathway except for factor 13, DIC,
Nonspecific inhibitor (lupus anticoagulant), Heparin, Coumadin, and direct
thromboplastin inhibitors
What is the normal levels of fibrinogen? - (ANSWER)150-400 mg/dL
Where is fibrinogen synthesized? - (ANSWER)In the liver
, 4
What is fibrinogen involved in? - (ANSWER)Forming the clot during secondary
hemostasis
What is fibrinogen considered? - (ANSWER)An acute phase reactant
When is fibrinogen increased? - (ANSWER)In inflammatory states, Smoking, and
Pregnancy
When is fibrinogen decreased? - (ANSWER)Liver disease, DIC, thrombolytic Rx,
and Hereditary dysfibrinogenemia
What is the normal value for D-Dimer? - (ANSWER)Less than 500
Someone who can climb a flight of stairs or walk up the hill would be considered
to be at what level a functional capacity? - (ANSWER)4 METs or above
What does the D-Dimer represent? - (ANSWER)The fibrin degradation of a blood
clot after fibrinolysis
When is the D-Dimer increased? - (ANSWER)In DVT, DIC, PE, and Malignancy