TEST BANK For Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition By Meyer Nursing, Verified Chapters 1 - 20, Complete Newest Version

, Test Bank ss



to accompany
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Psychopharmacology, Third Edition ss ss



Meyer • Quenzer ss ss




Chapter1: Principles of Pharmacology s ss ss ss




Multiple Choice s s




1. refer(s) to specific molecular changes that occur when a drug binds to a ss ss ss ss ss ss ss ss ss ss ss ss



particular target site or receptor, while
ss arethe resultingwidespreadalterations
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in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects ss ss ss



d. Drug action; drug effects
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Answer: d ss



Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is
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free to bind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. ss



c. bioavailability.
d. ED50.
Answer: c ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular
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target site or receptor are referred to as
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a. drug effects. ss



b. drug action. ss



c. side effects.
ss



d. placebo effects. ss



Answer: b ss



Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning ss



b. Geneticvariation
c. Drug competition ss



d. Expectation of outcome ss ss



Answer: c ss



Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. ss ss ss ss ss ss ss ss ss ss



a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administrationss ss



b. Lipid solubility ss



c. Depot binding ss



d. Drug action ss



Answer: d ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken ss ss ss ss ss ss



a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
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a. cerebrospinal fluid ss



b. blood–brain barrier ss



c. choroid plexus ss



d. phospholipid membrane ss



Answer: b ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orallyadministered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the
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way to general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. ss



b. choroid plexus. ss



c. area postrema.
ss



d. median eminence. ss




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, Answer: c ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
ss ss ss ss ss ss ss ss ss ss ofthe
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drug.
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a. pH; pKass



b. pKa; pH ss



c. concentration; lipid solubility ss ss



d. pH; concentration
ss



Answer: a ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
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b. ionization.
c. body temperature.
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d. the concentration of the drug.
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Answer: c ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble ss



Answer: a ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. ss



b. illicit drugs. ss



c. teratogens.
d. placental drugs. ss



Answer: c ss



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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Page 3 of 247
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