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Pharmacology Unit 1 – NU 578 Exam Review Q&A 2025/2026 – Drug Absorption, Distribution, Receptors, P450 System, Clinical Drug Laws & Tolerances

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This Pharmacology Unit 1 Study Guide for NU 578 (2025/2026) delivers a thoroughly curated set of 100+ expert-verified questions and answers, specifically designed for advanced nursing or health sciences students preparing for midterm or final pharmacology exams. Structured to reflect real exam content, the guide covers the core principles of pharmacokinetics, pharmacodynamics, and regulatory frameworks essential for safe and effective drug therapy. Key areas covered include: Pharmacokinetics: drug absorption, distribution, metabolism (P450 system), and excretion Drug administration: routes (oral, IM, IV, subQ), bioavailability, first-pass effect, and transdermal absorption Receptor pharmacology: agonists vs antagonists, receptor types (muscarinic, nicotinic, adrenergic), intrinsic activity Drug tolerances and safety concepts: pharmacodynamic tolerance, metabolic tolerance, tachyphylaxis, QT prolongation, black box warnings Special populations: pharmacokinetics in neonates, pediatrics, elderly, pregnancy, and breastfeeding Legislation and drug regulation: Controlled Substance Act, FDA drug testing phases, PREA, PCA, PDUFA, Beers List Pharmacodynamics: potency, efficacy, therapeutic range, toxic concentration, and adverse drug reactions Study design & safety testing: double-blind studies, placebo control, randomization, clinical trial phases Drug interactions, protein binding, ion trapping, and membrane permeability This guide is ideal for: MSN/DNP students enrolled in NU 578 or similar graduate pharmacology courses Pharmacy and physician assistant students in their foundational drug therapy modules Healthcare professionals preparing for pharmacology certification or advanced licensing exams Tutors and instructors developing assessment tools and review materials With detailed rationales and highly structured formatting, this document helps students master difficult concepts, understand real-world applications, and succeed on high-stakes assessments. Keywords: NU 578 pharmacology, drug absorption, drug metabolism, P450 enzyme system, receptor types, pharmacokinetics, QT interval drugs, FDA drug laws, pediatric pharmacology, black box warning, first-pass effect, bioavailability, drug excretion, pharmacodynamics, therapeutic index, elderly drug dosing, tolerance, FDA drug trials, adverse reactions

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Pharmacology-- NU 578
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Uploaded on
September 16, 2025
Number of pages
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Written in
2025/2026
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Pharmacology-- NU 578--Unit 1--#1
2025/2026 Exam Questions and Answers
| A+ Score Assured



Drug - 🧠 ANSWER ✔✔Any chemical that can affect living processes.


Pharmacology - 🧠 ANSWER ✔✔The study of drugs and their interactions

with living systems


Clinical Pharmacology - 🧠 ANSWER ✔✔The study of drugs in humans.


Therapeutics - 🧠 ANSWER ✔✔The use of drugs to diagnose, prevent, or

treat disease or to prevent pregnancy.


Effectiveness - 🧠 ANSWER ✔✔A drug that elicits the responses for which it

is given.

,Safety - 🧠 ANSWER ✔✔A drug that cannot produce harmful effects-- even

if administered in very high doses and for a very long time.


Selectivity - 🧠 ANSWER ✔✔A drug that elicits only the response for which it

is given


Properties of an Ideal drug - 🧠 ANSWER ✔✔Reversible action,

Predictability, Ease of Administration, Freedom from drug interaction, Low

Cost, Chemical Stability, Possession of a Simple Generic name.


Therapeutic Objective - 🧠 ANSWER ✔✔The objective of drug therapy is to

provide maximum benefit with minimum harm.

Factors determining intensity of drug responses - 🧠 ANSWER

✔✔Administration, Pharmacokinetics, Pharmacodynamics


Pharmacokinetics - 🧠 ANSWER ✔✔The processes that determine how

much of an administered dose gets to its sites of action.


Pharmacokinetic Processes - 🧠 ANSWER ✔✔The impact of the body on

drugs. Drug absorption, distribution, metabolism, and excretion.


Pharmacodynamics - 🧠 ANSWER ✔✔The impact of drugs on the body.

, Six Rights of Drug Administration - 🧠 ANSWER ✔✔Right drug, patient,

dose, route, time, and documentation.


Seven aspects of drug therapy - 🧠 ANSWER ✔✔Pre-administration

assessment, dosage and administration, evaluating and promoting

therapeutic effects, minimizing adverse effects, minimizing adverse

reactions, making PRN decisions, and managing toxicity.


Assessment Phase - 🧠 ANSWER ✔✔Collecting data about the patient--

Collection of baseline data needed to evaluate therapeutic responses--

Collection of baseline data needed to evaluate adverse effects--

Identification of high-risk patients--Assessment of the patient's capacity for

self-care


Analysis Phase - 🧠 ANSWER ✔✔Analyze the data collected and form

Nursing Dx--Judge the appropriateness of the prescribed regimen--Identify

potential health problems that the drug might cause--Determine the

patient's capacity for self-care.


Planning phase - 🧠 ANSWER ✔✔Nurse delineates specific interventions--

Defining goals-- Establishing priorities--Identifying specific interventions--

Establishing criteria for evaluating success


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