(The 5th Vital Sign) Questions With Complete Solutions
Reye Syndrome: Role of Aspirin (Liver Damage)
Tiredness
Nausea
Elevated AST
Elevated ALT
AST
Aspartate Aminotransferase.
It is an enzyme found primarily in the liver and heart.
XXX levels are measured in a blood test to assess liver function
and detect potential liver damage.
ALT
Alanine Aminotransferase
It is an enzyme primarily found in the liver.
Anti-inflammatory COX Inhibitors: ibuprofen
■Increased risk for HTN/MI (except ASA)
■GI upset, GI bleeding, bleeding risk
■Additive effect with opioids
■Take with full glass of water & food or milk
,■Sit upright after administration
Start low dose
Anti-inflammatory COX Inhibitors: ibuprofen (Dosage)
ibuprofen 3200 mg/24 hrs (800 mg QID)
Stop and Think: COX Inhibitors
■What are 1-2 high priority things the nurse should remember
for a patient taking cyclooxygenase Inhibitor agents?
–Interventions
–Assessments
■Indicate 1-2 high priority patient teaching points for these
patients.
■What is an appropriate NANDA for a patient
–At risk for taking cyclooxygenase Inhibitor agents?
■Side effects
Opioid Receptors: Mu Receptors
Endorphins
Morphine and fentanyl
Naloxone
Supraspinal & spinal analgesia
Respiratory depression
Sedation
, GI transit
Opioid Receptors: Mu Receptors (Endorphins)
endogenous
Opioid Receptors: Mu Receptors (Morphine & fentanyl)
agonist agents
Opioid Receptors: Mu Receptors (naloxone)
antagonist
Opioid Receptors: Mu Receptors (GI transit)
slows peristalsis
*Both opioid drugs and endorphins (your body's natural
opioids)...
can bind to the mu-opioid receptors on neurons
Opioid Analgesics
Moderate to Severe Pain
Pain relievers derived from or chemically related to the opium
poppy (very strong pain relievers)
Opioid Analgesics: Opioid Agonist
binds to opioid pain receptors in the brain for stimulation
Opioid Analgesics: Antagonist
–reverses effect – naloxone (Narcan)
Opioid Analgesics: Main Use