PHARMACOLOGY FOR NURSING PRACTICE,
2025/2026 WITH CORRECT/ACCURATE
ANSWERS
Bioavailability
the rate at and the extent to which a nutrient is absorbed and used/ >>>
is the proportion of a drug or other substance that, after administration,
enters the systemic circulation and is able to produce an active effect. In
simpler terms, it is the amount and rate at which a drug is absorbed into
the bloodstream.
Absorption
movement of a drug from its site of administration into the bloodstream
for distribution to the tissues >>> In pharmacology, absorption is the
process by which a drug travels from its site of administration to the
systemic circulation (the bloodstream). It is the first of four stages in
pharmacokinetics, which describes how the body processes drugs, often
abbreviated as ADME (Absorption, Distribution, Metabolism, Excretion).
Distribution
transport of a drug by the bloodstream to its site of action >>> In
pharmacology, drug distribution is the process by which a drug travels
from the systemic circulation to the various tissues and organs of the
body. It is the second phase of pharmacokinetics (ADME), following
absorption and preceding metabolism and excretion. A drug must be
, distributed to its site of action in order to have an effect, but it will also
spread to other areas, which can cause side effects.
Another word for metabolism?
Biotransformation >>> This term is often used to describe the specific
chemical changes a drug undergoes in the body.
Where does biotransformation occur?
Mainly occurs in the liver >>> Biotransformation, the process of
chemically altering substances like drugs and toxins, primarily occurs in
the liver. However, it can also take place in several other extrahepatic
(outside the liver) tissues
Biotransformation (metabolism)
- One or more biochemical reactions involving a parent drug >>> is the
process by which the body chemically alters substances, such as drugs,
into more water-soluble compounds that can be more easily eliminated.
The body achieves this by using enzymes, primarily in the liver, to change
the drug's chemical structure.
What does biotransformation produce?
- metabolite that can be inactive or active
Excretion
elimination of drugs from the body