PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE.5TH EXAM BANK WITH ALL
QUESTIONS AND CORRECT ANSWERS |GRADED A+| PASS!!
Nurse practitioner prescriptive authority is regulated by:
1. The National Council of State Boards of Nursing
2. The U.S. Drug Enforcement Administration
3. The State Board of Nursing for each state
4. The State Board of Pharmacy - ✔ANSWER 3. The State Board of Nursing for each state
The time required for the amount of drug in the body to decrease by 50% is called:
1. Steady state
2. Half-life
3. Phase II metabolism
4. Reduced bioavailability time - ✔ANSWER 2. Half-life
An agonist activates a receptor and stimulates a response. When given frequently
over time, the body may:
1. Upregulate the total number of receptors
2. Block the receptor with a partial agonist
3. Alter the drug's metabolism
4. Downregulate the numbers of that specific receptor - ✔ANSWER 4. Downregulate the
numbers of that specific receptor
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
,4. Leads to a decreased physiological response when combined with another drug - ✔ANSWER
2. Is modified by the concurrent administration of another drug
Instructions to a client regarding self-administration of oral enteric-coated tablets
should include which of the following statements?
1. "Avoid any other oral medicines while taking this drug."
2. "If swallowing this tablet is difficult, dissolve it in 3 ounces of orange juice."
3. "The tablet may be crushed if you have any difficulty taking it."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid." - ✔ANSWER 4. "To
achieve best effect, take the tablet with at least 8 ounces of fluid."
The major reason for not crushing a sustained-release capsule is that, if crushed, the coated
beads of the drugs could possibly result in:
1. Disintegration
2. Toxicity
3. Malabsorption
4. Deterioration - ✔ANSWER 2. Toxicity
Which of the following substances is the most likely to be absorbed in the
intestines rather than in the stomach?
1. Sodium bicarbonate
2. Ascorbic acid
3. Salicylic acid
4. Glucose - ✔ANSWER 1. Sodium bicarbonate
Which of the following variables is a factor in drug absorption?
1. The smaller the surface area for absorption, the more rapidly the drug is absorbed.
2. A rich blood supply to the area of absorption leads to better absorption.
,3. The less soluble the drug, the more easily it is absorbed.
4. Ionized drugs are easily absorbed across the cell membrane. - ✔ANSWER 2. A rich blood
supply to the area of absorption leads to better absorption.
An advantage of prescribing a sublingual medication is that the medication is:
1. Absorbed rapidly
2. Excreted rapidly
3. Metabolized minimally
4. Distributed equally - ✔ANSWER 1. Absorbed rapidly
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include:
1. Nurses know more about Pharmacology than other prescribers because they take it both in
their basic nursing program and in their APRN program
2. Nurses care for the patient from a holistic approach and include the patient in decision
making regarding their care.
3. APRNs are less likely to prescribe narcotics and other controlled substances.
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs
to have a physician supervising their practice. - ✔ANSWER 2. Nurses care for the patient
from a holistic approach and include the patient in decision making regarding their care.
Clinical judgment in prescribing includes:
1. Factoring in the cost to the patient of the medication prescribed
2. Always prescribing the newest medication available for the disease process
3. Handing out drug samples to poor patients
4. Prescribing all generic medications to cut costs - ✔ANSWER 1. Factoring in the cost to the
patient of the medication prescribed
Criteria for choosing an effective drug for a disorder include:
, 1. Asking the patient what drug they think would work best for them
2. Consulting nationally recognized guidelines for disease management
3. Prescribing medications that are available as samples before writing a prescription
4. Following U.S. Drug Enforcement Administration guidelines for prescribing - ✔ANSWER 2.
Consulting nationally recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of:
1. The demonstrated ability of nurse practitioners to control costs and improve patient
outcomes
2. The fact that nurse practitioners will be able to practice independently
3. The fact that nurse practitioners will have full reimbursement under health-care reform
4. The ability to shift accountability for Medicaid to the state level - ✔ANSWER 1. The
demonstrated ability of nurse practitioners to control costs and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys. - ✔ANSWER 1. Distribution
of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms - ✔ANSWER 3. Are rapidly
metabolized by the liver and may have little if any desired action
QUESTIONS AND CORRECT ANSWERS |GRADED A+| PASS!!
Nurse practitioner prescriptive authority is regulated by:
1. The National Council of State Boards of Nursing
2. The U.S. Drug Enforcement Administration
3. The State Board of Nursing for each state
4. The State Board of Pharmacy - ✔ANSWER 3. The State Board of Nursing for each state
The time required for the amount of drug in the body to decrease by 50% is called:
1. Steady state
2. Half-life
3. Phase II metabolism
4. Reduced bioavailability time - ✔ANSWER 2. Half-life
An agonist activates a receptor and stimulates a response. When given frequently
over time, the body may:
1. Upregulate the total number of receptors
2. Block the receptor with a partial agonist
3. Alter the drug's metabolism
4. Downregulate the numbers of that specific receptor - ✔ANSWER 4. Downregulate the
numbers of that specific receptor
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
,4. Leads to a decreased physiological response when combined with another drug - ✔ANSWER
2. Is modified by the concurrent administration of another drug
Instructions to a client regarding self-administration of oral enteric-coated tablets
should include which of the following statements?
1. "Avoid any other oral medicines while taking this drug."
2. "If swallowing this tablet is difficult, dissolve it in 3 ounces of orange juice."
3. "The tablet may be crushed if you have any difficulty taking it."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid." - ✔ANSWER 4. "To
achieve best effect, take the tablet with at least 8 ounces of fluid."
The major reason for not crushing a sustained-release capsule is that, if crushed, the coated
beads of the drugs could possibly result in:
1. Disintegration
2. Toxicity
3. Malabsorption
4. Deterioration - ✔ANSWER 2. Toxicity
Which of the following substances is the most likely to be absorbed in the
intestines rather than in the stomach?
1. Sodium bicarbonate
2. Ascorbic acid
3. Salicylic acid
4. Glucose - ✔ANSWER 1. Sodium bicarbonate
Which of the following variables is a factor in drug absorption?
1. The smaller the surface area for absorption, the more rapidly the drug is absorbed.
2. A rich blood supply to the area of absorption leads to better absorption.
,3. The less soluble the drug, the more easily it is absorbed.
4. Ionized drugs are easily absorbed across the cell membrane. - ✔ANSWER 2. A rich blood
supply to the area of absorption leads to better absorption.
An advantage of prescribing a sublingual medication is that the medication is:
1. Absorbed rapidly
2. Excreted rapidly
3. Metabolized minimally
4. Distributed equally - ✔ANSWER 1. Absorbed rapidly
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include:
1. Nurses know more about Pharmacology than other prescribers because they take it both in
their basic nursing program and in their APRN program
2. Nurses care for the patient from a holistic approach and include the patient in decision
making regarding their care.
3. APRNs are less likely to prescribe narcotics and other controlled substances.
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs
to have a physician supervising their practice. - ✔ANSWER 2. Nurses care for the patient
from a holistic approach and include the patient in decision making regarding their care.
Clinical judgment in prescribing includes:
1. Factoring in the cost to the patient of the medication prescribed
2. Always prescribing the newest medication available for the disease process
3. Handing out drug samples to poor patients
4. Prescribing all generic medications to cut costs - ✔ANSWER 1. Factoring in the cost to the
patient of the medication prescribed
Criteria for choosing an effective drug for a disorder include:
, 1. Asking the patient what drug they think would work best for them
2. Consulting nationally recognized guidelines for disease management
3. Prescribing medications that are available as samples before writing a prescription
4. Following U.S. Drug Enforcement Administration guidelines for prescribing - ✔ANSWER 2.
Consulting nationally recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of:
1. The demonstrated ability of nurse practitioners to control costs and improve patient
outcomes
2. The fact that nurse practitioners will be able to practice independently
3. The fact that nurse practitioners will have full reimbursement under health-care reform
4. The ability to shift accountability for Medicaid to the state level - ✔ANSWER 1. The
demonstrated ability of nurse practitioners to control costs and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys. - ✔ANSWER 1. Distribution
of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms - ✔ANSWER 3. Are rapidly
metabolized by the liver and may have little if any desired action
