Page 1 of 41
NU 578 UNIT 1 EXAM QUESTIONS AND
CORRECT DETAILED SOLUTIONS JUST
RELEASED THIS YEAR
QUESTION: When administering a medication known to be metabolized by the liver, the nurse
will closely monitor for adverse drug reactions in which patient? - ANSWER✔✔A 3-month-old
infant
QUESTION: Which statement about renal excretion in infants is true? - ANSWER✔✔Adult levels
of renal function are achieved by 1 year.
QUESTION: For medications that do not have established pediatric doses, the most common
method of extrapolating the appropriate dose is based on which measurement? -
ANSWER✔✔Body surface area
QUESTION: Which statement about intramuscular (IM) administration is incorrect? -
ANSWER✔✔Absorption of IM drugs becomes slower and more erratic in infancy than in
neonates.
, Page 2 of 41
QUESTION: Why are infants especially sensitive to drugs that affect CNS function? -
ANSWER✔✔The blood-brain barrier is not fully developed at birth.
QUESTION: Which of the following is not an example of age-related adverse drug effects? -
ANSWER✔✔Toxicity
QUESTION: The nurse is teaching young parents about medication administration in their child.
Which statements are appropriate to include in the teaching plan? (SATA) - ANSWER✔✔-"Guard
against spills and spitting to ensure that your child gets an accurate dose."
-"This calibrated spoon will help your child get an accurate dose."
-"Keep a medication record to make sure you do not give more than one dose at a time."
What is the moa for diuretics? - ANSWER✔✔Affects Maintenance of ecf volume and
composition
QUESTION: What is the Path that urine takes through the nephron -
ANSWER✔✔Glomerulus Prox convol tube Loop of Henle: Descrnding limb Ascending
limb DCT Collecting duct
QUESTION: What is the site of action for osmotic diuretics like
Mannitol? - ANSWER✔✔Proximal convoluted tubule
, Page 3 of 41
QUESTION: What is the Site of action for Thiazide diuretics like
HCTZ? - ANSWER✔✔Early distal convoluted tubule
QUESTION: What is the (site of action for Potassium sparing diuretics like
Spironolactone? - ANSWER✔✔Late distal convoluted tubule and collecting duct (distal nephron)
QUESTION: What is the sote of action for Loop diuretics like
Furosemide? - ANSWER✔✔Loop of Henle
QUESTION: Loop diuretics cause drug toxicity due to increased Na+ excretion. -
ANSWER✔✔Lithium excretion is decreased with hyponatremia and causes lithium toxicity.
QUESTION: Nephron order of diuretic action - ANSWER✔✔Osmotics Loops
Thiazides K+ sparing
QUESTION: PCT (proximal convoluted tubule) - ANSWER✔✔High resorptive capacity. About
65% of filtered Na+ and Cl resorbed here. Urine is isotonic
, Page 4 of 41
QUESTION: Freely permeable to water - ANSWER✔✔Descending limb loop of Henle
QUESTION: Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - ANSWER✔✔Distal
nephron: late DCT/CD
QUESTION: Causes transient deafness - ANSWER✔✔Furosemide
QUESTION: Only diuretic class that is ototoxic - ANSWER✔✔Loop diuretics (pg451)
QUESTION: Digoxin is potentiated with hypokalemia and ventricular dysrhythmias are greatly
increased. These diuretics promote K+ loss. - ANSWER✔✔Loop diuretics
Thiazide diuretics
QUESTION: Preferred drugs for mobilizing edema associated with mild to moderate failure -
ANSWER✔✔Thiazides
QUESTION: Diuretic Must be given parenterally. Only osmotic avail in US -
ANSWER✔✔Mannitol
NU 578 UNIT 1 EXAM QUESTIONS AND
CORRECT DETAILED SOLUTIONS JUST
RELEASED THIS YEAR
QUESTION: When administering a medication known to be metabolized by the liver, the nurse
will closely monitor for adverse drug reactions in which patient? - ANSWER✔✔A 3-month-old
infant
QUESTION: Which statement about renal excretion in infants is true? - ANSWER✔✔Adult levels
of renal function are achieved by 1 year.
QUESTION: For medications that do not have established pediatric doses, the most common
method of extrapolating the appropriate dose is based on which measurement? -
ANSWER✔✔Body surface area
QUESTION: Which statement about intramuscular (IM) administration is incorrect? -
ANSWER✔✔Absorption of IM drugs becomes slower and more erratic in infancy than in
neonates.
, Page 2 of 41
QUESTION: Why are infants especially sensitive to drugs that affect CNS function? -
ANSWER✔✔The blood-brain barrier is not fully developed at birth.
QUESTION: Which of the following is not an example of age-related adverse drug effects? -
ANSWER✔✔Toxicity
QUESTION: The nurse is teaching young parents about medication administration in their child.
Which statements are appropriate to include in the teaching plan? (SATA) - ANSWER✔✔-"Guard
against spills and spitting to ensure that your child gets an accurate dose."
-"This calibrated spoon will help your child get an accurate dose."
-"Keep a medication record to make sure you do not give more than one dose at a time."
What is the moa for diuretics? - ANSWER✔✔Affects Maintenance of ecf volume and
composition
QUESTION: What is the Path that urine takes through the nephron -
ANSWER✔✔Glomerulus Prox convol tube Loop of Henle: Descrnding limb Ascending
limb DCT Collecting duct
QUESTION: What is the site of action for osmotic diuretics like
Mannitol? - ANSWER✔✔Proximal convoluted tubule
, Page 3 of 41
QUESTION: What is the Site of action for Thiazide diuretics like
HCTZ? - ANSWER✔✔Early distal convoluted tubule
QUESTION: What is the (site of action for Potassium sparing diuretics like
Spironolactone? - ANSWER✔✔Late distal convoluted tubule and collecting duct (distal nephron)
QUESTION: What is the sote of action for Loop diuretics like
Furosemide? - ANSWER✔✔Loop of Henle
QUESTION: Loop diuretics cause drug toxicity due to increased Na+ excretion. -
ANSWER✔✔Lithium excretion is decreased with hyponatremia and causes lithium toxicity.
QUESTION: Nephron order of diuretic action - ANSWER✔✔Osmotics Loops
Thiazides K+ sparing
QUESTION: PCT (proximal convoluted tubule) - ANSWER✔✔High resorptive capacity. About
65% of filtered Na+ and Cl resorbed here. Urine is isotonic
, Page 4 of 41
QUESTION: Freely permeable to water - ANSWER✔✔Descending limb loop of Henle
QUESTION: Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - ANSWER✔✔Distal
nephron: late DCT/CD
QUESTION: Causes transient deafness - ANSWER✔✔Furosemide
QUESTION: Only diuretic class that is ototoxic - ANSWER✔✔Loop diuretics (pg451)
QUESTION: Digoxin is potentiated with hypokalemia and ventricular dysrhythmias are greatly
increased. These diuretics promote K+ loss. - ANSWER✔✔Loop diuretics
Thiazide diuretics
QUESTION: Preferred drugs for mobilizing edema associated with mild to moderate failure -
ANSWER✔✔Thiazides
QUESTION: Diuretic Must be given parenterally. Only osmotic avail in US -
ANSWER✔✔Mannitol