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PRITE Neuro Exam 2025/2026 – 270+ A+ Verified Questions & Answers | Brain Lesions, Stroke Syndromes, Dementia, Seizures, Sleep, Neurotransmitters & More

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This extensive document is a comprehensive, high-yield Q&A review for the 2025/2026 PRITE Neuroscience Examination, featuring over 270 verified and already graded A+ questions with correct answers. Perfectly aligned with the latest exam expectations, it covers core neuroscientific and neuropsychiatric topics frequently tested on residency and board-level exams. Key topics include: Cerebrovascular syndromes & stroke localization (e.g., MCA, PCA, ACA, brainstem strokes, hemorrhages) Neuroanatomy & brain-behavior relationships (e.g., parietal lobe lesions, basal ganglia, temporal lobe, subthalamic nucleus) Neurodegenerative disorders (Alzheimer’s, Parkinson’s, Huntington’s, Lewy body dementia, ALS) Seizure types & epilepsy syndromes (absence, focal, tonic-clonic, psychogenic) Neurotransmitter systems & pharmacology (dopamine, serotonin, norepinephrine, GABA, NMDA, antipsychotics, antidepressants) Sleep disorders & physiology (REM behavior disorder, insomnia, sleep paralysis, sleep apnea) Demyelinating and inflammatory disorders (MS, transverse myelitis, GBS) Neurological exam findings & localizations Clinical neuroimaging interpretation (CT, MRI, fMRI, PET) This document is best suited for: Psychiatry residents preparing for the PRITE Neurology residents and medical students studying for shelf exams, Step 1, Step 2 CK, or Step 3 Students in neuroscience, clinical neuropsychology, behavioral neurology, or neuropharmacology International medical graduates (IMGs) preparing for licensing exams with a neuro-heavy component Healthcare professionals seeking an evidence-based review of brain-focused clinical knowledge Each answer is fact-checked and reflects the most up-to-date clinical guidelines and exam-relevant knowledge as of 2025. The structured clinical vignettes help reinforce localization, diagnosis, management, and pathophysiology — all critical to excelling on exams and in real-life practice. Whether you’re preparing for PRITE, USMLE, ABPN, or other certifying exams, this resource offers a deep, well-organized, and trustworthy review of the neuroscience topics that matter most. Keywords: prite neuro exam, neuroscience q&a, stroke syndromes, dementia, neuroanatomy, neurotransmitters, brain lesions, multiple sclerosis, epilepsy, parkinson's disease, alzheimer's, ALS, neuroimaging, sleep disorders, cranial nerves, cerebral infarcts, aphasia, basal ganglia, frontal lobe, limbic system, psychopharmacology, EEG findings, movement disorders

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September 4, 2025
Number of pages
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Written in
2025/2026
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PRITE – Neuro 2025/2026 Exam
Questions and Verified Answers |
Already Graded A+



41 y/o without family h/o corticocerebellar degeneration presents with 3-

month h/o ataxia of gait/limbs, dysarthria, and progressive nystagmus. MRI

and CSF normal. 1) Antibody panel with presence of ? 2) What type of

tumor is likely present? - 🧠ANSWER ✔✔1) anti-Yo 2) Ovarian Carcinoma


Essential criterion for the declaration of brain death prior to organ donation

requires? - 🧠ANSWER ✔✔A positive apnea test


EEG that reveals posterior alpha and anterior beta activity is most likely to

have been obtained from whom? - 🧠ANSWER ✔✔A relaxed adult with eyes

closed

10 y/o child freq episodes brief lapses of consciousness without

premonitory sxs. Lasts 2-10 seconds, followed by immediate and full

,resumption of consciousness without awareness of what has happened.

These ictal episodes most likely caused by what kind szs: - 🧠ANSWER

✔✔Absence


Neuronal enzyme that is the target of drugs to treat Alzheimer's i.e.

galantamine and rivastigmine - 🧠ANSWER ✔✔Acetyl cholinesterase


Complications of a cerebellar hemorrhage? - 🧠ANSWER ✔✔Acute

hydrocephalus

Progressive weakness over several days - absent reflexes worse in lower

extremities - slow conduction velocity, conduction block - 🧠ANSWER

✔✔Acute inflammatory polyneuropathy


Weakness in limbs 2 weeks after a viral gastroenteritis. Weakness in

UE/LE, absent DTRs. Spinal fluid shows no cells and elevated protein. -

🧠ANSWER ✔✔Acute inflammatory polyneuropathy


Young pt recovering from flew-like illness w/ progressive weakness and

numbness of legs and feet. Weakness and numbness below middle of

thorax. Increased LE DTR's, extensor plantar reflexes. Urinary

incontinence. LP 23 mononuclear cells, protein level 37, nml glucose -

🧠ANSWER ✔✔Acute transverse myelitis

,The single most consistently documented and significant risk factor in the

epidemiology of tardive dyskinesia is? - 🧠ANSWER ✔✔Advanced age


Known risk factors for dementia: - 🧠ANSWER ✔✔Age, family hx, female,

Down Syndrome


What psychoactive drug produces amnesia? - 🧠ANSWER ✔✔Alcohol


What baseline labs should be taken before starting tacrine? - 🧠ANSWER

✔✔ALT and AST (baseline and f/u)


Clock drawing test is quickly administered and sensitive screen for which

d/o? - 🧠ANSWER ✔✔Alzheimer's


Individuals over 40yo with Down's syndrome frequently develops: -

🧠ANSWER ✔✔Alzheimer's


Amyloid precursor protein in - 🧠ANSWER ✔✔Alzheimer's Disease


Most common cause of dementia: - 🧠ANSWER ✔✔Alzheimer's disease


45 year old with gradual progressive weakness over the past 3-4 months,

particularly in the LUE. - 🧠ANSWER ✔✔Amyotrophic lateral sclerosis




3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED

, Atrophy of the intrinsic muscles of the right arm and forearm. Reflexes are

generally brisk, plantar reflexes are extensor. Electrophysiology shows

widespread fasciculations, fibrillation and sharp waves. Dx? - 🧠ANSWER

✔✔Amyotrophic lateral sclerosis


Gradually progressive weakness of legs and dysarthria over months -

fasciculations of tongue - prominent left upper extremity weakness - muscle

spasticity - brisk reflexes - normal sensation - 🧠ANSWER ✔✔Amyotrophic

lateral sclerosis

Fasciculations, fibrillations, positive sharp waves on EMG + progressive

weakness over several weeks - 🧠ANSWER ✔✔Amyotrophic lateral

sclerosis

70 y/o F sudden onset paralysis R foot and leg. R arm and hand lightly

affected. No aphasia or visual field deficit. Over weeks found with loss

bladder control, abulia and lack of spontaneity. Which vascular area: -

🧠ANSWER ✔✔Anterior cerebral artery (left)


55 y/o hx of weakness and clumsiness x several months. Difficulty w/ fine

motor tasks. Arm muscles twitch and cramp easily, weakening, atrophy.

Sensory, coordination, cranial nerve exams wnl. Underlying illness affects

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