Test Bank For Modern Blood Banking & Transfusion Practices 7th Edition By Denise M Harmening 9780803668881 Chapter 1-29 Complete Guide .

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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choicebb



Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis b b b b



b. Luebering-Rapoport shunt d. Methemoglobin reductase bb b b




2. A unit of blood was returned to the blood bank before it was spiked. Apparently the
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patient’s IV failed. The unit of blood was outside the blood bank for 35
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minutes. Which of the statements below is most accurate?
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a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of
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that time. b b b b



d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter b b b b b b b b b b of a platelet?
b b b b



a. 5 to 10 µm b b b b b b c. 1 to 2 µm b b b b b b



b. 2 to 4 µm b b b b b b d. 4 to 6 µm b b b b b b




4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is
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released to the tissues when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50%

5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count b b bb



b. Initial pH d. All of the above b b b b b b mm




6. Which of the following red blood cell morphologies may be present on the peripheral
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blood smear as a result of loss of RBC membrane?
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a. Spherocytes c. Burr cells mm



b. Target cells d. Schistocytes bb




7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend b b b b b b b b mm b b



c. An individual donating blood for a relative b b mm b b mm b b b b



d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism c. Oxygen transport
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b. Porphyrin synthesis d. Signal transduction b b b b




9. All of the following areas of red blood cell biology are crucial for normal erythrocyte
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survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
b b b b




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10. What is the correct biochemical composition of the
b b b b b b b b b b b b b b b b RBC membrane? b b



a. 52% protein, 40% lipid, 8% carbohydrate
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b. 40% protein, 8% lipid, 52% carbohydrate
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c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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11. All of the following biochemical changes are associated with loss of red blood cell
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storage viability upon
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except:
a. Decreased pH. b b c. Increased ATP level. bb bb



b. Loss of red blood cell function.
b b b b b b b b b b d. Decreased glucose consumption. b b b b




12. Which red blood cell preservative b b b b b b b b b b has a storage timeb b b b b b b b of b b 35 days? b b



a. ACD c. AS-1
b. CPDA-1 d. CPD

13. The RBC b b b b membrane b b is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water.

14. What percentage of platelets is sequestered in the spleen as functional reserve after
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being released from the bone marrow?
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a. 30% c. 10%
b. 50% d. 25%

15. What is the major b b b b b b b b biochemical consideration in platelet storage? b b mm b b b b



a. Glucose metabolism b b c. Production of carbon dioxide b b b b mm



b. Oxygen supply b b d. Regulation of pH bbm b b m b b mm mm




16. What would the hemoglobin-oxygen dissociation curve depict in a patient
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exhibiting clinical signs of alkalosis?
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a. Normal c. Shift to the right b b b b b b



b. Shift to the left b b d. None of the above
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17. Name the main lipid components b b b b b b mm b b of a red blood cell
b b mm b b b b b b membrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A bb




18. The ABO blood groups bb b b mm b b were discovered in 1901 by whom?
mm b b b b b b b b



a. Charles Drew mm c. Loutit and Mollison b b b b



b. Karl Landsteiner mm d. Edward Lindeman b b




19. A standing order of platelets was shipped to your facility by your supplier. It was
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inadvertently left in the corner of the department until discovered 36 hours later.
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What would the appropriate action be for the blood banker?
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a. If the temperature in the box was 22 +/- 2°C and the platelet swirl
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seemed OK, it would be OK to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The
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unit should be discarded because the pH has probably dropped too
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low and platelet activation has been compromised.
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c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK
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