NR565
Chamberlain: NR 565 / Final Exam Question Bank
(Latest ): Advanced Pharmacology
Fundamentals.
2 hour post-load plasma glucose in an oral glucose tolerance test greater than
or equal to 200 mg/dL. The test uses a glucose load containing the
equivalent of 75 g anhydrous glucose dissolved in water. - ANS Diabetes
Mellitis (glucose tolerance test)
HgB A1c > or equal to 6.5 - ANS Diabetes Mellitis Labs
Pre-Diabetes Glucose tolerance test - ANS Plasma glucose 140 to 199 mg/dL
(IGT) 2 hours post-ingestion of standard glucose load (75 g) or
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HgB A1c 5.7-6.4 - ANS Prediabetes
Diabetes Treatment Step 1 - ANS Lifestyle Changes
Metformin
Diabetes Treatment Step 2 - ANS Step 1 (lifestyle and metformin)
Second Drug
Diabetes Treatment Step 3 - ANS Step 1+2
Third Drug
Diabetes Treatment step 4 - ANS Consider GLP-1 Agonist if Step 3 includes
basal insulin
Insulin Human - ANS Pancreas Basal Cells in langeran's
Insulin accelerant - ANS Corticosteroids
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Compound Effect Insulin Medication - ANS Sulfonyureas (ides)
Rapid ACTING INsulin - ANS Lispro (Humalog)
Aspart (Novolog)
Glulisine (Apidra)
(15-30m) onset, duration 3-6 hour
Short Acting insulin - ANS - Regular (Humulin R, Novolin R)
- Onset 30 min-1 hr
- peak 2-5 hr
- duration 6-10 hr
Negative feedback system in hypothyroidism - ANS Production of T3 and T3
by the hypothalamus and pituitary gland
TRH - ANS from the hypothalamus controls the release of TSH
TSH (negative feedback loop) - ANS acts as the gauge for the hypothalamus
to know if it needs more or less TRH and subsequently more or less TSH
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Acute symptoms of diabetes plus casual plasma glucose concentration greater
than or equal to 200 mg/dL.
Fasting plasma glucose greater than or equal to 126 mg/d (8hrs) - ANS
Diabetes Mellitis
Long Acting Ins - ANS glargine (Lantus)
detemir (Levemir)
(onset 70 minutes) duration 18-24 hours
Ultralong In - ANS Tresiba
Onset (30-90 min)
duration >24hours
Metformin black box warning - ANS -lactic acidosis increased with CKD,
liver disease, severe infection, excessive alcohol intake, shock, or
hypoexmia
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