Already Solved Solutions 2025\2026
Edition.
What are the 3 characteristics of Asthma - Answer Bronchoconstriction
Airway Inflammation
Reversible airflow limitation
Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/
bronchospasms due to beta blocker meds? - Answer Ipratropium Bromide
What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond
promptly and completely to SABA? - Answer Systemic Corticosteroids
Which bacterial infections predispose exacerbations of asthma - Answer M. Pneumoniae and
C. Pneumoniae
Is routine use of antimicrobials recommended for acute exacerbations of asthma - Answer No,
only use when likelihood of acute bacterial respiratory tract infection
Name short acting beta agonist - Answer albuterol, levalbuterol, bitolerol, pirbuterol,
terbutaline
What does a SABA do? - Answer acts directly by relaxing bronchial smooth muscles.
What do long-term pharmacologic agents accomplish for asthma pt. - Answer act primarily to
attenuate airway inflammation.
Why take long-term pharmacologic agents for asthma daily? - Answer to achieve and maintain
control of persistent asthma independent of symptoms.
What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? -
Answer daily anti-inflammatory therapy with inhaled corticosteroids
,1st. line treatment agent for all pt w/persistent asthma (long term controller) - Answer Inhaled
Corticosteroids
How often to most patient use inhaled corticosteroids? - Answer Twice daily to provide
adequate control.
How long can it take to see maximum response of inhaled corticosterioids? - Answer Months
What can a patient do to reduce side effects of inhaled corticosteroids? - Answer Rinse mouth
after each use
A patient has an exacerbation of asthma, what is the most effective treatment to achieve
prompt control? - Answer Systemic (oral) corticosteroids
Dose of oral corticosteroids for children during exacerbation of asthma - Answer 1-2
mg/kg/day.
Can be either a single dose or divided BID.
MAX 60 mg/day
Dose of oral corticosteroids for adults during exacerbation of asthma - Answer 40-60 mg/day
either as a single dose of divided BID
Duration of treatment of oral corticosteroids for asthma exacerbation - Answer 3-10 days or
until symptoms resolve
(no evidence that tapering dose of PO steroids prevents relapse)
When treating exacerbation of asthma, what is the preferred treatment plan? - Answer
Alternate days rather than daily treatment.
What additional medications are required to be given concurrent with systemic corticosteroids
to prevent corticosteroid induced bone mineral loss? - Answer Vitamin D and Calcium
Should systemic corticosteroids be rapidly discontinued? - Answer No, to prevent adrenal
insufficiency
, What is the mechanism of action of mediator inhibitors? - Answer prevent asthma symptoms,
improve airway function in pt w/mild persistent of exercise induce asthma
When are mediator inhibitors effective? - Answer Before allergen exposure or exercise
Do not relieve asthmatic symptoms once present.
Name the Long acting beta 2 agonist (LABA) for asthma - Answer Salmeterol and Formoteol
How are LABA's delivered? - Answer dry powder
What are LABA's used for - Answer Long term prevention of asthma symptoms
Nocturnal symptoms
Prevention of exercise induced bronchospasm
Should LABA be used as monotherapy - Answer NO
linked to fatal asthma when used alone
has no anti-inflammatory effects- so use w/a corticosteroid.
What does LABA + low or medium dose of corticosteroids given together provide for the
patient. - Answer The equivalent to what would be if doubled the inhaled corticosteroid.
Name the action of anticholinergic agents, short acting muscarinic agents (SAMA) and long
acting muscarinic agents (LAMA) - Answer Reverse vagally medicated bronchospasm but NOT
allergen or exercise induced broncospasms
Is Ipratropium bromide (SAMA) as effect as a SABA for relief of acute bronchospasm - Answer
No
What is the benefit to adding Tiotropium to therapy bronchodilator (salmeterol) or
inadequately controlled low-dose inhaler. - Answer Improves lung function and reduces
frequency of asthma exacerbations.
Name the phosphodiesterase inhibitor used for asthma - Answer theophylline