Development Final Review Exam And
100% Accurate Verified Answers
2025\2026 Edition.
What three steps does drug development consist of? - Answer Discover, optimization, and
development
What is meant by a lead component in medicinal chemistry?
A. A drug containing the element lead
B. A leading drug in a particular area of medicine
C. A compound that acts as the starting point for drug design and development
D. A drug that is normally first to be prescribed for a particular ailment - Answer C
What are the first three stages of design and development? - Answer Identify target disease,
identify drug target, and establish testing procedures
What are stages 4-6 of drug design and development? - Answer find a lead compound, SAR,
and identify a pharmacophore
What are strged 7-9 of drug design and development? - Answer Drug design (target
interactions), design (pharmacokinetics props), toxicological and safety
What are steps 10-12 of drug design and development? - Answer Chemical development,
patenting, and clinical trials
How many phases are there in clinical trials? - Answer 4 - Phase I , Phase II, Phase III and Phase
IV
How do you identify a target disease? - Answer Has to be a priority for the pahrmaceutical
industry
What is the average length of time to develop a drug? - Answer 15 years
, File NDA - Answer new drug application
What are the four types of drug targets? - Answer Lipids, proteins, nucleic acids, and
carbohydrates
What is the most common drug target? - Answer proteins
What is the difference between receptors and enzymes? - Answer Enzymes will catalyze the
reaction
You want the drug to have target _________ - Answer selectivity
Target selectivity can affect both - Answer in the body and between species
bioassay - Answer test to ascertain a drug's availability in a biological model
in vitro - Answer carried out outside the body
in vivo - Answer carried out on live organisms
In vivo tests take longer than - Answer in vitro tests
You can identify possible side effects in ________ tests - Answer in vivo
You can identify therapeutic index in _______ tests - Answer in vivo
You cannot identify pro drugs with ______ tests - Answer in vitro
enzyme inhibition tests allow you to find - Answer competitive or non-comptetive inhibition
You can find IC (strength of inhibition) with - Answer enzyme inhibition tests