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NU 664D / NU664D Exam 2: (Latest Update 2025 / 2026) Primary Care Adult Woman I | Questions & Answers | 100% Correct | Grade A. Regis

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1. clinical manifestations of primary amenorrhea: absence of menarche by age 15 2. differential diagnoses for primary amenorrhea: pregnancy, turner syndrome, mullerian agenesis, delay of puberty, PCOS, weight loss, excessive exercise, anorexia 3. diagnostic workup for primary amenorrhea: pelvic US, HCG, FSH, TSH, prolactin 4. clinical manifestations of secondary amenorrhea: absence of menses for more than 3 cycle intervals or 6 months in women who were previously menstruating 5. what is the provera challenge?: start with progestin for 10 days and then stop. if bleeding starts again, she has estrogen but is not ovulating. If she does not start bleeding again, she is ovulating but has outflow tract problem like scarring or adhesions. bleed = not ovulating no bleed = ovulating, scarring adhesions 6. when is the provera challenge used?: for diagnostic of secondary amenorrhea with normal labs and history of uterine instrumentation 7. turner's syndrome clinical manifestations: 1. hypogonadism -absent/non functioning sex chromosome (45X0) -> gonadal dysgenesis -> rudimentary, fibrosed ovaries -> primary amenorrhea in 80% (menopause before menarche) or early ovarian failure with secondary amenorrhea (20%), delayed secondary sex characteristics (absence of breasts), infertility in a majority of patients 2. physical exam -short stature, webbed neck, prominent ears, posterior hairline, broad chest with hypoplastic widely spaced nipples, (congenital lymphedema seen in neonates), short 4th metacarpals, high arched palate, nail dysplasia, may have hearing loss 3. cardiovascular -coarctation of the aorta -MVP -bicuspid aortic valves -aortic dissection -HTN 4. renal -congenital abnormalities (horseshoe kidney) -hydronephrosis 5. endocrine -osteoporosis -hypothyroidism -DM -dyslipidemia

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NU664D Exam2




NU 664D / NU664D Exam 2: (Latest Update
) Primary Care Adult Woman I |
Questions & Answers | 100% Correct | Grade
A. Regis



1. clinical manifestations of primary amenorrhea: absence of menarche

by age 15

2. differential diagnoses for primary amenorrhea: pregnancy, turner

syndrome, mullerian agenesis, delay of puberty, PCOS, weight loss, excessive

exercise, anorexia

3. diagnostic workup for primary amenorrhea: pelvic US, HCG, FSH,

TSH, prolactin

4. clinical manifestations of secondary amenorrhea: absence of menses

for more than 3 cycle intervals or 6 months in women who were previously

menstruating 5. what is the provera challenge?: start with progestin for 10

days and then stop. if bleeding starts again, she has estrogen but is not






, ovulating. If she does not start bleeding again, she is ovulating but has outflow

tract problem like scarring or adhesions.

bleed = not ovulating

no bleed = ovulating, scarring adhesions

6. when is the provera challenge used?: for diagnostic of secondary

amenorrhea with normal labs and history of uterine instrumentation

7. turner's syndrome clinical manifestations: 1. hypogonadism

-absent/non functioning sex chromosome (45X0) -> gonadal dysgenesis ->

rudimentary, fibrosed ovaries -> primary amenorrhea in 80% (menopause

before menarche) or early ovarian failure with secondary amenorrhea (20%),

delayed secondary sex characteristics (absence of breasts), infertility in a

majority of patients


2. physical exam

-short stature, webbed neck, prominent ears, posterior hairline, broad chest

with hypoplastic widely spaced nipples, (congenital lymphedema seen in

neonates), short 4th metacarpals, high arched palate, nail dysplasia, may have

hearing loss

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