Midterm Exam: Nr565/ Nr 565
Advanced Pharmacology Care
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5% - ✔✔✔ANSWER-
ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a
statin or fibrate - ✔✔✔ANSWER-Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides -
✔✔✔ANSWER-Ezetimibe
, Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation - ✔✔✔ANSWER-Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects - ✔✔✔ANSWER-Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation -
✔✔✔ANSWER-Organic Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB - ✔✔✔ANSWER-Ranolazine
Contraindications
Avoid in children under 10 - ✔✔✔ANSWER-Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply -
✔✔✔ANSWER-CCB Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms - ✔✔✔ANSWER-HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand - ✔✔✔ANSWER-CCB Stable Angina
Advanced Pharmacology Care
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5% - ✔✔✔ANSWER-
ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a
statin or fibrate - ✔✔✔ANSWER-Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides -
✔✔✔ANSWER-Ezetimibe
, Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation - ✔✔✔ANSWER-Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects - ✔✔✔ANSWER-Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation -
✔✔✔ANSWER-Organic Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB - ✔✔✔ANSWER-Ranolazine
Contraindications
Avoid in children under 10 - ✔✔✔ANSWER-Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply -
✔✔✔ANSWER-CCB Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms - ✔✔✔ANSWER-HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand - ✔✔✔ANSWER-CCB Stable Angina
