,Comprehensive Test Bank for Marieb Human Anatomy &
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter 1: The Human Body: An
Orientation.
Item 1
Chapter & Subtopic: Chapter 1 — 1.1 Form determines function
(Topics of Anatomy) — Key concept: structural levels
Stem: Which level of organization is directly between the
cellular and organ system levels?
A. Atom
B. Tissue
C. Organ
D. Organism
Correct Answer: B
Rationale (correct): Tissues are groups of similar cells
performing a common function and lie between cells and
organs in the structural hierarchy. (Marieb, Ch.1, Section 1.2).
Incorrect explanations:
A. Atoms are the chemical level below molecules, not between
cells and organ systems.
C. An organ is made of multiple tissue types, so it is above the
tissue level.
D. Organism is the highest level (whole body), not between cells
,and systems.
Teaching Point: Tissue = cells organized into a functional unit.
Item 2
Chapter & Subtopic: Chapter 1 — 1.1 Studying Anatomy — Key
concept: gross vs microscopic anatomy
Stem: A nurse examining biopsy slides under a microscope is
practicing which branch of anatomy?
A. Gross anatomy
B. Systemic anatomy
C. Microscopic anatomy
D. Developmental anatomy
Correct Answer: C
Rationale (correct): Microscopic anatomy studies structures too
small to see with the naked eye, such as cells and tissues on
biopsy slides (Marieb, Ch.1, Section 1.1).
Incorrect explanations:
A. Gross anatomy examines large structures visible without a
microscope.
B. Systemic anatomy studies organ systems, not microscopic
slides.
D. Developmental anatomy studies changes from conception
onward.
Teaching Point: Microscopic anatomy = cells & tissues under
microscope.
, Item 3
Chapter & Subtopic: Chapter 1 — 1.1 Topics of Physiology —
Key concept: physiology levels
Stem: Which physiologic subdiscipline focuses on how the
kidneys regulate blood volume?
A. Cardiovascular physiology
B. Renal physiology
C. Neurophysiology
D. Endocrine physiology
Correct Answer: B
Rationale (correct): Renal physiology studies kidney function,
including regulation of blood volume, electrolyte balance, and
waste excretion (Marieb, Ch.1, Section 1.1).
Incorrect explanations:
A. Cardiovascular physiology focuses on the heart and blood
vessels, not primary kidney function.
C. Neurophysiology concerns nervous system function.
D. Endocrine physiology studies hormones; kidneys are the
organ of interest for blood volume.
Teaching Point: Renal physiology = kidneys regulate fluid and
electrolytes.
Item 4
Chapter & Subtopic: Chapter 1 — 1.1 Complementarity of
Structure & Function — Key concept: form informs function
Stem: A nurse notes that alveoli are thin-walled and richly
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter 1: The Human Body: An
Orientation.
Item 1
Chapter & Subtopic: Chapter 1 — 1.1 Form determines function
(Topics of Anatomy) — Key concept: structural levels
Stem: Which level of organization is directly between the
cellular and organ system levels?
A. Atom
B. Tissue
C. Organ
D. Organism
Correct Answer: B
Rationale (correct): Tissues are groups of similar cells
performing a common function and lie between cells and
organs in the structural hierarchy. (Marieb, Ch.1, Section 1.2).
Incorrect explanations:
A. Atoms are the chemical level below molecules, not between
cells and organ systems.
C. An organ is made of multiple tissue types, so it is above the
tissue level.
D. Organism is the highest level (whole body), not between cells
,and systems.
Teaching Point: Tissue = cells organized into a functional unit.
Item 2
Chapter & Subtopic: Chapter 1 — 1.1 Studying Anatomy — Key
concept: gross vs microscopic anatomy
Stem: A nurse examining biopsy slides under a microscope is
practicing which branch of anatomy?
A. Gross anatomy
B. Systemic anatomy
C. Microscopic anatomy
D. Developmental anatomy
Correct Answer: C
Rationale (correct): Microscopic anatomy studies structures too
small to see with the naked eye, such as cells and tissues on
biopsy slides (Marieb, Ch.1, Section 1.1).
Incorrect explanations:
A. Gross anatomy examines large structures visible without a
microscope.
B. Systemic anatomy studies organ systems, not microscopic
slides.
D. Developmental anatomy studies changes from conception
onward.
Teaching Point: Microscopic anatomy = cells & tissues under
microscope.
, Item 3
Chapter & Subtopic: Chapter 1 — 1.1 Topics of Physiology —
Key concept: physiology levels
Stem: Which physiologic subdiscipline focuses on how the
kidneys regulate blood volume?
A. Cardiovascular physiology
B. Renal physiology
C. Neurophysiology
D. Endocrine physiology
Correct Answer: B
Rationale (correct): Renal physiology studies kidney function,
including regulation of blood volume, electrolyte balance, and
waste excretion (Marieb, Ch.1, Section 1.1).
Incorrect explanations:
A. Cardiovascular physiology focuses on the heart and blood
vessels, not primary kidney function.
C. Neurophysiology concerns nervous system function.
D. Endocrine physiology studies hormones; kidneys are the
organ of interest for blood volume.
Teaching Point: Renal physiology = kidneys regulate fluid and
electrolytes.
Item 4
Chapter & Subtopic: Chapter 1 — 1.1 Complementarity of
Structure & Function — Key concept: form informs function
Stem: A nurse notes that alveoli are thin-walled and richly
