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Questions and Answers with
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Rationale)UPDATED!!!
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THIS EXAM CONTAINS
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..100%SURE PASS
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..MULTIPLE CHOICE (SINGLE ANSWER
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..MULTIPLE RESPONSE
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,2020 HESI Pharmacology Version 1 – Questions 1
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through 100 VV
1) A nurse is caring for a client with hyperparathyroidism and notes that the client's
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serum calcium level is 13 mg/dL. Which medication should the nurse prepare to
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administer as prescribed to the client?
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1. Calcium chloride VV
2. Calcium gluconate VV
3. Calcitonin (Miacalcin) VV
4. Large doses of vitamin D
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VV Rationale:
The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing
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hypercalcemia. Calcium gluconate and calcium chloride are medications used for
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the treatment of tetany, which occurs as a result of acute hypocalcemia. In
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hypercalcemia, large doses of vitamin D need to be avoided. Calcitonin, a thyroid
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hormone, decreases the plasma calcium level by inhibiting bone resorption and
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lowering the serum calcium concentration.
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2.) Oral iron supplements are prescribed for a 6-year-old child with iron
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deficiency anemia. The nurse instructs the mother to administer the iron with
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which best food item?
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1. Milk
2. Water
3. Apple juice VV
4. Orange juice VV 4. Orange juice
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VV Rationale:
Vitamin C increases the absorption of iron by the body. The mother should be
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instructed to administer the medication with a citrus fruit or a juice that is high in
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vitamin C. Milk may affect absorption of the iron. Water will not assist in absorption.
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Orange juice contains a greater amount of vitamin C than apple juice.
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3.) Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The
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nurse monitors the client, knowing that which of the following would indicate the
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presence of systemic toxicity from this medication?
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1. Tinnitus
2. Diarrhea
3. Constipation
4. Decreased respirations VV 1. Tinnitus VV
VV Rationale:
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,Salicylic acid is absorbed readily through the skin, and systemic toxicity
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(salicylism) can result. Symptoms include tinnitus, dizziness, hyperpnea, and
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psychological disturbances. Constipation and diarrhea are not associated with
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salicylism.
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4.) The camp nurse asks the children preparing to swim in the lake if they
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have applied sunscreen. The nurse reminds the children that chemical
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sunscreens are most effective when applied:
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1. Immediately before swimming VV VV
2. 15 minutes before exposure to thesun
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3. Immediately before exposure to thesun VV VV VV VV V
4. At least 30 minutes before exposure to the sun 4. At least 30
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minutesbefore exposure to the sun
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Rationale:
Sunscreens are most effective when applied at least 30 minutes before exposure
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to the sun so that they can penetrate the skin. All sunscreens should be reapplied
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after swimming or sweating.
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5.) Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury.
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When applying the medication, the client complains of local discomfort and
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burning. Which of the following is the most appropriate nursing action?
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1. Notifying the registered nurse VV VV VV
2. Discontinuing the medication VV VV
3. Informing the client that this is normal VV VV VV VV VV VV
4. Applying a thinner film than prescribed to the burn site 3. Informing the client
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VV that this is normal
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Rationale:
Mafenide acetate is bacteriostatic for gram-negative and gram-positive organisms
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and is used to treat burns to reduce bacteria present in avascular tissues. The client
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should be informed that the medication will cause local discomfort and burning
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and that this is a normal reaction; therefore options 1, 2, and 4 are incorrect
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6.) The burn client is receiving treatments of topical mafenide acetate (Sulfamylon)
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to the site of injury. The nurse monitors the client, knowing that which of the
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following indicates that a systemic effect has occurred?
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1. Hyperventilation
2. Elevated blood pressure VV VV
3. Local pain at the burnsite
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4. Local rash at theburn site
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, Rationale:
Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal
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excretion of acid, thereby causing acidosis. Clients receiving this treatment
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should be monitored for signs of an acid-base imbalance (hyperventilation). If
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this occurs, the medication should be discontinued for 1 to 2 days. Options 3
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and 4 describe local rather than systemic effects. An elevated blood pressure
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may be expected from the pain that occurs with a burn injury.
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7.) Isotretinoin is prescribed for a client with severe acne. Before the administration
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of this medication, the nurse anticipates that which laboratory test will be
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prescribed?
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1. Platelet count VV
2. Triglyceride level VV
3. Complete blood count VV VV
4. White blood cell count 2. Triglyceridelevel
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VV Rationale:
Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be
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measured before treatment and periodically thereafter until the effect on the
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triglycerides has been evaluated. Options 1, 3, and 4 do not need to be monitored
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specifically during this treatment.
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8.) A client with severe acne is seen in the clinic and the health care provider (HCP)
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prescribes isotretinoin. The nurse reviews the client's medication record and
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would contact the (HCP) if the client is taking which medication?
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1. Vitamin A VV
2. Digoxin (Lanoxin) VV
3. Furosemide (Lasix) VV
4. Phenytoin (Dilantin) VV 1. Vitamin A
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VV Rationale:
Isotretinoin is a metabolite of vitamin A and can produce generalized intensification
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of isotretinoin toxicity. Because of the potential for increased toxicity, vitamin A
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supplements should be discontinued before isotretinoin therapy. Options 2, 3, and 4
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are not contraindicated with the use of isotretinoin.
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9.) The nurse is applying a topical corticosteroid to a client with eczema. The
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nurse would monitor for the potential for increased systemic absorption of the
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medication if the medication were being applied to which of the following body
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areas?
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1. Back
2. Axilla
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