lOMoAR cPSD|
lOMoARcP SD|447246286
724628 6
Adrenergic
Agonists
o Adrenergic- sympathetic nervous system
o Increase HR, increase oxygen (bronchodilation), Increase blood flow, Resp rate increase,
pupils dilate, blood glucose increase
o Patient going to be very alert and awake
o Mimic norepinephrine and Epinephrine
o It can affect the heart, bronchi (lungs), GI
tract Urinary bladder, eyes
Alpha 1
o Increases cardiac contractility, vasoconstriction
o Dilates pupils
o Increases bladder & prostate
contraction Beta 1
o Increases cardiac contractility, heart rate
o Increases renin secretion, blood pressure
Beta
2 o Decreases GI tone and motility
o Bronchodilation
o Increases blood flow in skeletal muscles
o Relaxes smooth muscles of uterus
o Activates liver glycogenolysis – increases blood sugar
Remember beta 1 – 1 heart so it mainly affects the
heart Beta 2 – 2 lungs so it mainly affects the lungs
Alpha 1 increases the blood pressure (A- Arteries)
Epinephrine
Nonselective – stimulates alpha 1, beta 1, and beta 2
, lOMoAR cPSD| 47246286
▪ Alpha 1 increases the blood pressure
▪ Beta 1 increases the heart rate
▪ Beta 2 promotes bronchodilation
Increase HR, increase oxygen (bronchodilation), Increase blood flow, Resp rate increase, pupils dilate,
blood glucose increase
Emergency Drug
Uses
o Anaphylaxis, anaphylactic shock
o Bronchospasms, status asthmaticus
o Cardiogenic shock, cardiac arrest
Therapeutic response when Heart rate between 60-
100 Side effects/Adverse reactions
o GI disturbances
o Sweating, headache, insomnia, dizziness, agitation, anxious
o Hyperglycemia
o Palpitations, cardiac dysrhythmia
o Tachycardia (heart rate over 100 adverse reaction)
o Hypertension (above 140/90 adverse reaction)
Contraindications
o Tachycardia
, lOMoAR cPSD| 47246286
o Glaucoma (due to dilation of the pupils is going to increase pressure in the eye)
o Labor (vasoconstricting of the vessels occur and will stop blood flow to the baby)
Caution
o Hypertension
o Prostatic hypertrophy
o Diabetes mellitus
Interactions
o MAOI’s tricyclic antidepressants – intensify and prolong effect
o Beta blockers – block effect
o Digoxin – can increase risk of dysrhythmia
o Lab – increases blood sugar
Assessment
o Vital signs (pt will be placed on a monitor)
o Medication/medical history (what if they were on morphine and overdose on it then we can
just give naloxone and we can use epinephrine)
o Current symptoms
o Baseline glucose level
Nursing interventions
o Monitor blood pressure, heart rate and urine output
o Monitor IV site for infiltration. Give IV push slowly (1 mg/minute) unless in cardiac arrest we
will give it faster
o Patient on cardiac monitor when giving IV
o Monitor for side effects/adverse reactions – report hypertension, irregular heart rate, tachycardia
o Monitor blood glucose in diabetic patients with long term use (albuterol)
Teaching
o The side effects/adverse reactions to report (palpitations)
o Avoid drugs that increase the blood pressure such as cold medication and diet pills
o Avoid adrenergic when breastfeeding
o Nasal sprays should only be used 3-5 days
o Take medication as prescribed
o How to use inhaled drugs or drops – return demonstration
Epi-Pen Teaching
o If pt uses it they need to call 911
o Inform provider if EpiPen is used more than twice a week
o Have EpiPen with you at all times
o Do not refrigerate EpiPen but store in cool, dark place
o Use EpiPen at first sign of reaction
o Inspect the contents for particles and do not use if particles are pink or
brown o Inject subcutaneously in the outer thigh and hold in place for 5-
10 seconds o After administration massage the injection site
o Report side effects/adverse reactions
lOMoARcP SD|447246286
724628 6
Adrenergic
Agonists
o Adrenergic- sympathetic nervous system
o Increase HR, increase oxygen (bronchodilation), Increase blood flow, Resp rate increase,
pupils dilate, blood glucose increase
o Patient going to be very alert and awake
o Mimic norepinephrine and Epinephrine
o It can affect the heart, bronchi (lungs), GI
tract Urinary bladder, eyes
Alpha 1
o Increases cardiac contractility, vasoconstriction
o Dilates pupils
o Increases bladder & prostate
contraction Beta 1
o Increases cardiac contractility, heart rate
o Increases renin secretion, blood pressure
Beta
2 o Decreases GI tone and motility
o Bronchodilation
o Increases blood flow in skeletal muscles
o Relaxes smooth muscles of uterus
o Activates liver glycogenolysis – increases blood sugar
Remember beta 1 – 1 heart so it mainly affects the
heart Beta 2 – 2 lungs so it mainly affects the lungs
Alpha 1 increases the blood pressure (A- Arteries)
Epinephrine
Nonselective – stimulates alpha 1, beta 1, and beta 2
, lOMoAR cPSD| 47246286
▪ Alpha 1 increases the blood pressure
▪ Beta 1 increases the heart rate
▪ Beta 2 promotes bronchodilation
Increase HR, increase oxygen (bronchodilation), Increase blood flow, Resp rate increase, pupils dilate,
blood glucose increase
Emergency Drug
Uses
o Anaphylaxis, anaphylactic shock
o Bronchospasms, status asthmaticus
o Cardiogenic shock, cardiac arrest
Therapeutic response when Heart rate between 60-
100 Side effects/Adverse reactions
o GI disturbances
o Sweating, headache, insomnia, dizziness, agitation, anxious
o Hyperglycemia
o Palpitations, cardiac dysrhythmia
o Tachycardia (heart rate over 100 adverse reaction)
o Hypertension (above 140/90 adverse reaction)
Contraindications
o Tachycardia
, lOMoAR cPSD| 47246286
o Glaucoma (due to dilation of the pupils is going to increase pressure in the eye)
o Labor (vasoconstricting of the vessels occur and will stop blood flow to the baby)
Caution
o Hypertension
o Prostatic hypertrophy
o Diabetes mellitus
Interactions
o MAOI’s tricyclic antidepressants – intensify and prolong effect
o Beta blockers – block effect
o Digoxin – can increase risk of dysrhythmia
o Lab – increases blood sugar
Assessment
o Vital signs (pt will be placed on a monitor)
o Medication/medical history (what if they were on morphine and overdose on it then we can
just give naloxone and we can use epinephrine)
o Current symptoms
o Baseline glucose level
Nursing interventions
o Monitor blood pressure, heart rate and urine output
o Monitor IV site for infiltration. Give IV push slowly (1 mg/minute) unless in cardiac arrest we
will give it faster
o Patient on cardiac monitor when giving IV
o Monitor for side effects/adverse reactions – report hypertension, irregular heart rate, tachycardia
o Monitor blood glucose in diabetic patients with long term use (albuterol)
Teaching
o The side effects/adverse reactions to report (palpitations)
o Avoid drugs that increase the blood pressure such as cold medication and diet pills
o Avoid adrenergic when breastfeeding
o Nasal sprays should only be used 3-5 days
o Take medication as prescribed
o How to use inhaled drugs or drops – return demonstration
Epi-Pen Teaching
o If pt uses it they need to call 911
o Inform provider if EpiPen is used more than twice a week
o Have EpiPen with you at all times
o Do not refrigerate EpiPen but store in cool, dark place
o Use EpiPen at first sign of reaction
o Inspect the contents for particles and do not use if particles are pink or
brown o Inject subcutaneously in the outer thigh and hold in place for 5-
10 seconds o After administration massage the injection site
o Report side effects/adverse reactions
