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HESI Comprehensive Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

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HESI Comprehensive Questions and Answers | Latest Version | 2025/2026 | Correct & Verified A client with pneumonia is receiving IV antibiotics. Which finding indicates the treatment is effective? A. Temperature 101°F B. White blood cell count 15,000 C. Clear breath sounds and improved oxygen saturation D. Productive cough with yellow sputum A client is prescribed warfarin. Which instruction is most important? A. Take medication with milk B. Limit intake of citrus fruits C. Report unusual bruising or bleeding immediately D. Expect frequent headaches as a side effect A client with COPD is prescribed oxygen at 2 L/min via nasal cannula. Why is this rate important? 2 A. It improves lung compliance B. Higher oxygen can suppress respiratory drive C. It prevents atelectasis D. It reduces bronchospasms A nurse is assessing a client receiving digoxin. Which finding requires immediate action? A. Heart rate 72/min B. Heart rate 48/min C. Blood pressure 130/70 mmHg D. Respiratory rate 20/min A client with diabetes reports blurry vision and frequent urination. Which complication is most likely? A. Hypoglycemia B. Hyperglycemia C. Hyponatremia D. Hypocalcemia 3 A client is scheduled for surgery and says, “I’m afraid I won’t wake up.” Which nursing response is best? A. “Don’t worry, everything will be fine.” B. “Why would you think that way?” C. “It sounds like you are feeling anxious. Tell me more about your fears.” D. “Many people feel scared before surgery.” A postpartum client with a firm fundus reports heavy bleeding. What is the priority action? A. Administer IV fluids B. Assess for bladder distension C. Call the provider immediately D. Increase oxytocin infusion A client with heart failure is prescribed furosemide. Which dietary teaching is correct? A. Avoid bananas B. Eat more processed foods C. Increase potassium-rich foods D. Restrict protein intake 4 A nurse is teaching a client prescribed sertraline for depression. Which statement indicates understanding? A. “I can stop this medication once I feel better.” B. “It may take a few weeks before I notice improvement.” C. “This medication will make me sleepy all the time.” D. “I can drink alcohol with this medication.” A client is receiving blood transfusion and develops fever and chills. What is the nurse’s first action? A. Stop the transfusion immediately B. Document the reaction C. Administer acetaminophen D. Notify the blood bank A client with cirrhosis has ascites and shortness of breath. Which intervention is most important? A. Encourage ambulation

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HESI Comprehensive

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August 17, 2025
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Written in
2025/2026
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HESI Comprehensive Questions and
Answers | Latest Version | 2025/2026 |
Correct & Verified
A client with pneumonia is receiving IV antibiotics. Which finding indicates the treatment is

effective?

A. Temperature 101°F

B. White blood cell count 15,000


✔✔C. Clear breath sounds and improved oxygen saturation


D. Productive cough with yellow sputum




A client is prescribed warfarin. Which instruction is most important?

A. Take medication with milk

B. Limit intake of citrus fruits


✔✔C. Report unusual bruising or bleeding immediately


D. Expect frequent headaches as a side effect




A client with COPD is prescribed oxygen at 2 L/min via nasal cannula. Why is this rate

important?



1

,A. It improves lung compliance


✔✔B. Higher oxygen can suppress respiratory drive


C. It prevents atelectasis

D. It reduces bronchospasms




A nurse is assessing a client receiving digoxin. Which finding requires immediate action?

A. Heart rate 72/min


✔✔B. Heart rate 48/min


C. Blood pressure 130/70 mmHg

D. Respiratory rate 20/min




A client with diabetes reports blurry vision and frequent urination. Which complication is most

likely?

A. Hypoglycemia


✔✔B. Hyperglycemia


C. Hyponatremia

D. Hypocalcemia




2

,A client is scheduled for surgery and says, “I’m afraid I won’t wake up.” Which nursing response

is best?

A. “Don’t worry, everything will be fine.”

B. “Why would you think that way?”


✔✔C. “It sounds like you are feeling anxious. Tell me more about your fears.”


D. “Many people feel scared before surgery.”




A postpartum client with a firm fundus reports heavy bleeding. What is the priority action?

A. Administer IV fluids


✔✔B. Assess for bladder distension


C. Call the provider immediately

D. Increase oxytocin infusion




A client with heart failure is prescribed furosemide. Which dietary teaching is correct?

A. Avoid bananas

B. Eat more processed foods


✔✔C. Increase potassium-rich foods


D. Restrict protein intake


3

, A nurse is teaching a client prescribed sertraline for depression. Which statement indicates

understanding?

A. “I can stop this medication once I feel better.”


✔✔B. “It may take a few weeks before I notice improvement.”


C. “This medication will make me sleepy all the time.”

D. “I can drink alcohol with this medication.”




A client is receiving blood transfusion and develops fever and chills. What is the nurse’s first

action?


✔✔A. Stop the transfusion immediately


B. Document the reaction

C. Administer acetaminophen

D. Notify the blood bank




A client with cirrhosis has ascites and shortness of breath. Which intervention is most important?

A. Encourage ambulation


✔✔B. Place the client in high Fowler’s position



4

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