Antipsychotic MedicationsNR546 Week 3 very well answered for a good grades

Antipsychotic MedicationsNR546 Week 3 very well answered for a good grades Pines - ANSWERSbind more potently to the 5HT 2A receptor than the D2. Sedation is common and relates to a high affinity for histamine. These medications have the least risk of EPS but a high risk for weight gain and metabolic abnormalities. olanzapine (Zyprexa) - ANSWERStreatment of schizophrenia age 13 and older Special Comments: Best tolerated antipsychotic Risk: High metabolic risk Highest risk for weight gain, blood dyscrasias, QT prolongation, cardiovascular disease, cerebrovascular effects, hyperglycemia, and hyperprolactinemia quetiapine (Seroquel) - ANSWERSuse for schizophrenia ages 13 and older Risk: Moderate metabolic risk Low EPS risk Risk of orthostatic hypotension, blood dyscrasias (neutropenia, leukopenia, and agranulocytosis), QT prolongation, weight gain, and renal and hepatic impairment asenapine (Saphris) - ANSWERSapproved for schizophrenia ages 10 and older Special Comments: Available in sublingual and transdermal patch Risk: Low metabolic risk clozapine (Clozaril) - ANSWERSApproved for treatment-resistant schizophrenia and chronic suicidal behavior in schizophrenia or schizoaffective disorder Not indicated in acute presentation of schizophrenia Special Comments: The Absolute Neutrophil Count (ANC) must be 1500/mm3 when used and requires initial and weekly monitoring of WBC, granulocyte, and neutrophil counts. Risk: High metabolic risk Highest risk for weight gain. Low EPS risk. Black box warning: may cause severe neutropenia Contraindicated in liver disease and hepatic failure Not a first-choice mediation for treating schizophrenia Psychosis - ANSWERSmakes people feel out of control and out of touch with reality Antipsychotic meds can help relieve sx positive symptoms of schizophrenia - ANSWERShallucinations delusions Thought disorder Hostility Excitability negative sx of schizophrenia - ANSWERSthe "A's" alogia asociality anhedonia affective flattening amotivation cognitive sx of schizophrenia - ANSWERSAttention Working memory Verbal memory Visual memory Executive functioning Processing speed Social conditioning Affective Sx of Schizophrenia - ANSWERSdepression anxiety suicidality motor sx of schizophrenia - ANSWERSextrapyramidal symptoms (parkinsonism, dyskinesia) motor delay dyscoordination sx of psychosis - ANSWERShallucinations delusions disorganized speech disorganized behavior distortions of reality Inappropriate or very strong emotions or apathy Withdrawn behavior Sudden decline in self-care