What are telangictasias - CORRECT ANS - fine, irregular red lines produced by capillary dilation
Which type of collagen provides the scaffolding of articular cartilage? - CORRECT ANS - Collagen
IX is the collagen, or scaffolding, that holds articular cartilage in place.
What is the term for a chronic inflammatory joint disease characterized by stiffening and fusion of the
spine and sacroiliac joints? - CORRECT ANS - Ankylosing spondylitis is the result of chronic
inflammation in the spine and sacroiliac joints resulting in stiffening and fusion of the spine.
What is needed for osteoclast activation - CORRECT ANS - RANKL
What leads to primary osteoporosis - CORRECT ANS - alterations in RANKL/OPG system lead to
dysregulation
Type IX collagen does what - CORRECT ANS - The glue that holds together the type two collagen
acaffold of articular cartliage
Osteosarcoma looks like what - CORRECT ANS - most common malignant primary bone tumor. Has
a moth eaten pattern of bone destruction.
Giant cells in myelogenic tumors affect what gender more often - CORRECT ANS - females
What is the hallmark of the OA process - CORRECT ANS - Loss of proteoglycans from the articular
cartilage
, What is chronic fatigue syndrome - CORRECT ANS - (Myalgic encephalomyelitis)- a debilitating
and complex disorder characterized by profound fatigue, musculoskeletal pain, cognitive impairment,
unrefreshing sleep, impaired neurologic energy production, and immune impairments.
What layer of the skin has langerhans-cells with dendritic processes and immune function -
CORRECT ANS - epidermis
What is a vesicle - CORRECT ANS - elevated, superficial, filled with serous fluid, less than 1cm. Ex-
herpes, varicella
What is osteomyelitis - CORRECT ANS - infection of bone
Describe the most likely route by which the microorganisms reached the patient's bone.
Submit and Compare, displayed below - CORRECT ANS - The microorganisms likely reached her
bone by extension from the nearby infected ulcer at the base of her big toe.
Name the microorganism that is most likely causing the osteomyelitis.
Submit and Compare, displayed below - CORRECT ANS - staphylococcus aureus is the most
common pathogen, although many diabetic foot ulcers are polymicrobial infections.
Describe sequestrum. - CORRECT ANS - Sequestrum is an area of necrotic bone that separates from
the healthy bone.
What is the most common cause of a corner metaphyseal fracture in a child younger than 12 months
of age? - CORRECT ANS - A transverse tibia fracture resulting in a straight horizontal break across
the tibial shaft is a common cause of a corner metaphyseal fracture in a child under 12 months of age.
A transverse fracture is caused by direct force, often involving the metaphysis, and is considered a
sign of suspected physical abuse, though transverse fractures could be caused by other types of
trauma. A spiral fracture, caused by a twisting force, also often involves the metaphysis and is also a
sign of suspected physical abuse.
Evaluation of osteogenesis imperfecta - CORRECT ANS - hould include genetic testing, bone scans,
and bone density testing. Osteogenesis imperfecta is a disorder caused by a genetic mutation in the
gene that encodes for type I collagen, the main component of bone and blood vessels. The Sillence