MSC Test 2 Questions and Answers Fully Solved Latest Version 2025-2026
Tissue donated from another individual, same species - AnswersDefine Allograft
Are multi-nucleated cells developed from Hematopoietic Stem Cells - AnswersDefine
Osteoclasts
Chondrocytes - AnswersThe mature cells that makeup just 2% of healthy articular cartilage are
called?
Scaffold - AnswersDefine Osteoconduction
MSC's are summoned to the site, thanks to chemotaxis signals, and some differentiate into
osteoblasts which lay new osteoid - AnswersExplain the role of Mesenchymal Stem Cells in the
bone formation cascade?
Proteoglycan, Collagen - AnswersTypes of scaffolds in cartilage include?
False - AnswersThe epiphyseal line is found in the epiphysis? (T/F)
TRUE - AnswersRANKL ignites osteoclasts precursor fusion and osteoclastic activity? (T/F)
stimulates development of cell rich bone marrow stores - AnswersBone Marrow Stimulation:
TRUE - AnswersChondrocytes come from Mesenchymal Stem Cells lineage (T/F)
Corticosteroid Injections, PRP - AnswersNon-invasive treatment options for joint preservation
include? (Select All)
The process in which the graft material resorbs (or old necrotic bone is resorbed) and new bone
matrix is laid down - AnswersDefine Creeping Substitution:
Cell migration courtesy of a chemical signal - AnswersChemotaxis is....?
Grows Bone - AnswersExplain the role of the body's natural Bone Morphogenic Protein (BMP) in
the bone formation process?
FALSE - AnswersBone marrow aspiration/concentration, a type of autograft is considered an
invasive treatment option? (T?F)
Oral Surgeon
Sports Medicine Physician
Neurosurgeons
Podiatrist - AnswersWhich specialties are likely targets for biologic sales? (Select all that apply)
Eat dead cells and foreign particles, Engulf and digest necrotic tissues and debris, Are part of
, the white blood cell lineage - AnswersMacrophages: (select all that apply)
1) Anatomic Reduction
2) Stable internal fixation
3) Preserve Blood Supply
4) Early Mobilization - AnswersThe 4 main AO principles of bone healing are:
Programmed Cell Death - AnswersDefine Apoptosis
1) Inflammation
2) Soft Callus
3) Hard Callus
4) Remodeling - AnswersIn Order, the FOUR steps of bone healing are:
Growth Factor
Signaling Protein
Inductive - AnswersSynonyms for cytokine: (Select all that apply)
osteochondral autograft transfer system - AnswersDefine OATS Procedure?
Hyaline Cartilage is composed of Type II collagen whereas fibrocartilage is composed of Type I
& II Collagen - AnswersThe MAIN STRUCTURAL difference between hyaline cartilage and
fibrocartilage is which of the following?
FALSE - AnswersRANKL is secreted by osteoclasts, bind to the receptors of OPCs which
differentiate into osteoblasts? (T/F)
This product contains "viable cells" - AnswersRelative to a biologic technology that we may sell,
when a biologic material is described as having an "osteogenic" property, what does this mean
about this product/technology?
1) Fibrocartilage
2) Hyaline Cartilage
3) Elastic Cartilage - AnswersThe three types of cartilage found in the human body include?
Risk of pain and injury that may occur after autograft harvesting - AnswersDefine Donor Site
Morbidity?
osteochondral autograft transfer system - AnswersOATS Procedure stands for?
Tissue donated from another individual, same species - AnswersDefine Allograft
Are multi-nucleated cells developed from Hematopoietic Stem Cells - AnswersDefine
Osteoclasts
Chondrocytes - AnswersThe mature cells that makeup just 2% of healthy articular cartilage are
called?
Scaffold - AnswersDefine Osteoconduction
MSC's are summoned to the site, thanks to chemotaxis signals, and some differentiate into
osteoblasts which lay new osteoid - AnswersExplain the role of Mesenchymal Stem Cells in the
bone formation cascade?
Proteoglycan, Collagen - AnswersTypes of scaffolds in cartilage include?
False - AnswersThe epiphyseal line is found in the epiphysis? (T/F)
TRUE - AnswersRANKL ignites osteoclasts precursor fusion and osteoclastic activity? (T/F)
stimulates development of cell rich bone marrow stores - AnswersBone Marrow Stimulation:
TRUE - AnswersChondrocytes come from Mesenchymal Stem Cells lineage (T/F)
Corticosteroid Injections, PRP - AnswersNon-invasive treatment options for joint preservation
include? (Select All)
The process in which the graft material resorbs (or old necrotic bone is resorbed) and new bone
matrix is laid down - AnswersDefine Creeping Substitution:
Cell migration courtesy of a chemical signal - AnswersChemotaxis is....?
Grows Bone - AnswersExplain the role of the body's natural Bone Morphogenic Protein (BMP) in
the bone formation process?
FALSE - AnswersBone marrow aspiration/concentration, a type of autograft is considered an
invasive treatment option? (T?F)
Oral Surgeon
Sports Medicine Physician
Neurosurgeons
Podiatrist - AnswersWhich specialties are likely targets for biologic sales? (Select all that apply)
Eat dead cells and foreign particles, Engulf and digest necrotic tissues and debris, Are part of
, the white blood cell lineage - AnswersMacrophages: (select all that apply)
1) Anatomic Reduction
2) Stable internal fixation
3) Preserve Blood Supply
4) Early Mobilization - AnswersThe 4 main AO principles of bone healing are:
Programmed Cell Death - AnswersDefine Apoptosis
1) Inflammation
2) Soft Callus
3) Hard Callus
4) Remodeling - AnswersIn Order, the FOUR steps of bone healing are:
Growth Factor
Signaling Protein
Inductive - AnswersSynonyms for cytokine: (Select all that apply)
osteochondral autograft transfer system - AnswersDefine OATS Procedure?
Hyaline Cartilage is composed of Type II collagen whereas fibrocartilage is composed of Type I
& II Collagen - AnswersThe MAIN STRUCTURAL difference between hyaline cartilage and
fibrocartilage is which of the following?
FALSE - AnswersRANKL is secreted by osteoclasts, bind to the receptors of OPCs which
differentiate into osteoblasts? (T/F)
This product contains "viable cells" - AnswersRelative to a biologic technology that we may sell,
when a biologic material is described as having an "osteogenic" property, what does this mean
about this product/technology?
1) Fibrocartilage
2) Hyaline Cartilage
3) Elastic Cartilage - AnswersThe three types of cartilage found in the human body include?
Risk of pain and injury that may occur after autograft harvesting - AnswersDefine Donor Site
Morbidity?
osteochondral autograft transfer system - AnswersOATS Procedure stands for?
