lOMoARcPSD|44532475
Module 5 Quiz
Furosemide (Lasix) 3 questions (loop diuretics):
Act on the thick ascending loop of Henle to block reabsorption of sodium and
chloride.
Sodium and water are lost along with potassium, calcium, and magnesium.
Most effective diuretics available are very potent; can cause marked depletion of
water and electrolytes. ***
Generally reserved for situations that require rapid or massive mobilization of
fluid.
*** Useful in patients with severe renal impairment (can promote diuresis even
when GFR and renal blood flow are low).
Should be taken in the morning due to diuresis.
Can be used in Ivy form for emergent treatment of pulmonary edema or acute
heart failure.
Assess vital signs, daily weights (report gain or loss >2lbs. in 24 hours), &
electrolytes.
Caution patients about possible orthostatic hypotension.
Side effects:
o Dehydration
o Hypotension
o Electrolyte imbalances
Hyponatremia
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, lOMoARcPSD|44532475
Hypokalemia
o Hyperglycemia
o Ototoxicity
Drug interactions:
o Digoxin-secondary to low potassium
o Ototoxic drugs
o Lithium-secondary to low sodium
o Antihypertensive agents
o NSAIDS-can counteract diuretic effect
!!WARNING!!
o When administering a dose into an IV, with a syringe, it must be pushed
SLOWLY, not to exceed 20mg/min. ***
o Too rapid IV push is associated with ringing in the ears (tinnitus) and
permanent hearing loss (ototoxicity), especially when combined with other
ototoxic drugs like gentamicin or vancomycin.
o Best practice is to use an infusion pump with drug library.
Potassium supplements:
- Patients on potassium-wasting diuretics are usually on potassium supplements.
- Monitoring of serum potassium levels is essential.
- Normal serum potassium levels are 3.5 - 5.0.
Loop diuretics (furosemide), how do they work in the nephron?
Downloaded by madiba South Africa stuvia ()
Module 5 Quiz
Furosemide (Lasix) 3 questions (loop diuretics):
Act on the thick ascending loop of Henle to block reabsorption of sodium and
chloride.
Sodium and water are lost along with potassium, calcium, and magnesium.
Most effective diuretics available are very potent; can cause marked depletion of
water and electrolytes. ***
Generally reserved for situations that require rapid or massive mobilization of
fluid.
*** Useful in patients with severe renal impairment (can promote diuresis even
when GFR and renal blood flow are low).
Should be taken in the morning due to diuresis.
Can be used in Ivy form for emergent treatment of pulmonary edema or acute
heart failure.
Assess vital signs, daily weights (report gain or loss >2lbs. in 24 hours), &
electrolytes.
Caution patients about possible orthostatic hypotension.
Side effects:
o Dehydration
o Hypotension
o Electrolyte imbalances
Hyponatremia
Downloaded by madiba South Africa stuvia ()
, lOMoARcPSD|44532475
Hypokalemia
o Hyperglycemia
o Ototoxicity
Drug interactions:
o Digoxin-secondary to low potassium
o Ototoxic drugs
o Lithium-secondary to low sodium
o Antihypertensive agents
o NSAIDS-can counteract diuretic effect
!!WARNING!!
o When administering a dose into an IV, with a syringe, it must be pushed
SLOWLY, not to exceed 20mg/min. ***
o Too rapid IV push is associated with ringing in the ears (tinnitus) and
permanent hearing loss (ototoxicity), especially when combined with other
ototoxic drugs like gentamicin or vancomycin.
o Best practice is to use an infusion pump with drug library.
Potassium supplements:
- Patients on potassium-wasting diuretics are usually on potassium supplements.
- Monitoring of serum potassium levels is essential.
- Normal serum potassium levels are 3.5 - 5.0.
Loop diuretics (furosemide), how do they work in the nephron?
Downloaded by madiba South Africa stuvia ()
