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Exam (elaborations)

Pharmacology Exam 1 Questions with Solution Updated 2025/2026

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Access the Pharmacology Exam 1 Questions with Solution, updated for 2025/2026. Contains verified exam-style questions and accurate answers covering major drug classifications, mechanisms of action, therapeutic uses, side effects, and safe medication practices. Perfect for nursing, pharmacy, and healthcare students preparing for their first pharmacology exam.

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August 10, 2025
Number of pages
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Pharm Exam 1 Questions
BOLD - my answers
BLUE - correct answers

1. A client taking phenytoin suddenly develops hives. What is the best explanation for this
occurrence and the nurse’s best response?
a. A hypersensitive (excessive) response and the dose should be reduced
b. A random idiosyncratic response that will not disrupt treatment plan
c. A paradoxical response related to the body’s attempt to maintain homeostasis
and will resolve over time
d. An allergic response and the medication should be stopped
2. A client is given a new medication and reports nausea within an hour after taking the
drug. The nurse knows that nausea is an expected side effect. What is the best action?
a. Report the symptom to the pharmacist to modify the order
b. Administer next dose as scheduled and tell client to report more symptoms
c. Hold the drug and let the provider know before administering the next dose
d. Explore non-pharmacological measures to minimize the side effect
3. A nurse is preparing to administer medication to a hospitalized patient who has been
taking lithium for 3 days. The client is complaining of mild nausea, fatigue, and dry
mouth. The client’s lithium levels are 0.8 mEq/L. What is the best response?
a. Administer the dose and tell the client the expected side effects are
temporary
b. Request an order for amiloride
c. Contact the provider to request an order for serum electrolytes
d. Hold the dose and notify the provider of the client’s lithium levels
4. What is the nurse’s best response when a client refuses medication?
a. Remind the client of the consequences associated with noncompliance
b. Investigate the reason the client is refusing
c. Bring in a social worker for counselling
d. Call the provider and explore alternative medications
5. Why is IV diazepam used in the treatment of status epilepticus?
a. The IV product has a 5 day half-life to prevent reoccurance
b. The medication resolves continual seizures rapidly with no loading dose
c. The drug alleviates suffering when the family requests euthanasia
d. Diazepam is a secondary medication to make the patient forget the event
6. A client taking levodopa/carbidopa reports feeling lightheaded/dizzy, especially when
standing from a sitting position. What will the nurse expect the provider to recommend?
a. Alpha-adrenergic antagonist
b. Drug holiday
c. Increase salt and water intake
d. Amantadine
7. A client taking interferon beta-1a reports feeling depressed. What is the nurse’s best
action?
a. Notify the provider of these symptoms




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b. Request an order for an antidepressant
c. Reassure the client that the symptoms will subside
d. Skip the next dose and report if symptoms persist
8. Which of the following is least likely to occur during the assessment phase of drug
therapy?
a. Developing outcomes for effective responses to drug therapy
b. Determining if there are any financial restraints
c. Identify client’s level of understanding
d. Obtain information about clients current medication use
9. After administering a medication, the client complains of an upset stomach. The nurse
recognizes this as a negative effect of the drug and identifies it as which of the following?
a. Side effect
b. Intended effect
c. Teratogenic effect
d. Paradoxical effect
10. A child diagnosed with ADHD begins taking a CNS stimulant. Which statement by the
child's parents indicates a need for further teaching?
a. This medication will help my child improve attention and focus
b. This drug will make my child more impulsive at school
c. I will make sure my child takes this in the morning after breakfast
d. I should report insomnia and appetite loss to the provider
11. Which side effects of a cholinesterase inhibitor would be most concerning to a nurse?
a. Nausea, vomiting, and diarrhea
b. Symptomatic bradycardia that may lead to fainting
c. Confusion and memory impairment
d. Dizziness and headache
12. A client experiencing alcohol withdrawal is given a benzodiazepine. Why is this helpful?
a. Benzodiazepines relieve muscle spasms and spasticity
b. Benzodiazepines exacerbate alcohol withdrawal symptoms
c. Benzodiazepines suppress symptoms brought on by alcohol withdrawal
d. Alcohol does not interact with benzodiazepines
13. A client is taking a FGA and the nurse notices the client has trouble speaking, chewing
and observes slow, worm-like movement of the tongue. The nurse suspects which of the
following adverse effects is occurring?
a. Parkinsonism
b. Acute dystonia
c. Tardive dyskinesia
d. Akathisia
14. A client is receiving lamotrigine as a treatment for partial seizures. Which assessment
finding will lead the nurse to stop the drug and contact the provider immediately?
a. Dizziness
b. Rash
c. Insomnia
d. Loss of taste




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