NR507 Midterm Exam Study
Guide-1 Questions and
Answers 2025
, NR507 Midterm Exam Study Guide
General Study Tips and Recommendations
✓ Topics and content on guides are intended to focus student attention when reading/studying and
some topics may be repeated in multiple chapters.
✓ Multiple test items are derived from the same topic areas to encourage deeper comprehension.
✓ Students must have a broad understanding of content and not simply memorize passages in
textbooks or articles.
✓ Information contained in the chapters as well as boxes and table within the chapters may
include test items.
✓ Exam questions represent various levels of cognitive learning. You are expected to analyze,
synthesis, and evaluate patient scenarios in order to answer the questions.
✓ Read all of the answers BEFORE reading the stem of the question. This will help you focus on the
key content and not get distracted by extraneous information. Once you have selected your
answer, read the question one more time to ensure that the best answer has been chosen.
✓ Utilize your time well by not rushing. You will have plenty of time to read each question for
understanding before you select your final answer.
Major Content Topics:
Alterations in Immunity & Inflammation
• Hypersensitivity
• Immunodeficiency
• Autoimmunity
Alterations in Hematologic Function
• Anemia
• Role of erythropoietin in RBC production
• Primary site of RBC production
• Anemia
• Microcytic anemias
• Macrocytic anemias
• Normocytic anemias
• Hemoglobinopathies
Alterations of Cardiovascular Function
• Coronary artery disease
Definition: imbalance between myocardial oxygen demand and supply from coronary arteries
Prolonged O2 demand on the heart leads to Myocardial Infraction
Cause: Atherosclerosis of coronary arteries with myocardial ischemia
, PATHO: LDL in blood overtime starts to stick to artery wall. It grows over time which limits the blood flow
to heart. As people do activity, sob and chest pain with activities. Goes away with rest.-stable angina
Unstable: plaque rupture: artery wall messed up, body sends clotting factors to artery to repair it and
forms a thrombus.
ACS: Thrombus keeps growing and growing which stops blood flow : unstable angina (chest pain
unrelieved by rest and nitroglycerin doesn’t relieve chest pain.
Once thrombus completes blocks blood flow= MI(heart muscle dies)
Non-modifiable: age(men > 45 y/o ; women > 55 y/o), family history
modifiable:: Elevated LDL(BAD) & Decreased HLD(Good), Hypertension, Diabetes, smoking
Present as Stable Angina, Prinzmetal Angia, Acute Coronary Syndrome(unstable angina, Non ST
elevation, MI, NSTEMI, STEMI Chronic Ischemia heart disease, sudden cardiac death)
Less common cause:
Coronary Embolus: A-Fib, Infective endocarditis, left atrial or ventricular thrombus, cardiac cath
Vasculitis(CAD in Children): * Kawasaki disease (medium vessel vasculitis cause coronary artery
aneurysm)
Vasospasm: reduce blood flow
Aortic Valve Stenosis: not enough blood to coronaries leading to myocardial ischemia
Causes of concentric ventricular hypertrophy: HTN, hypertrophic cardiomyopathy d/t more heart
muscle to supply
Stable(Plaque) Angina(hasn’t ruptured)
(Near -total occlusion w/ no infraction of b/c atherosclerotic plaque grows slowly gives heart to develop
**collateral circulationRerouting**)- that supplies the hyperperfused area
Secondary to Myocardial Ischemia(Reversible Cell Injury)
Atherosclerotic plaque occluding > 75% of coronary artery lumen
S/S chest pain with activity, sob, fatigue-goes away with rest
Infraction: Irreversible cell injury or death
Described as :
Deep poorly localized squeezing, crushing, suffocating, retrosternal pain(jaw, neck, arm)
Other symptoms: sob, nausea, vomiting, diaphoresis, fatigue, dizziness
*** Reproducible during: Physical exertion or Emotional Stress***
Guide-1 Questions and
Answers 2025
, NR507 Midterm Exam Study Guide
General Study Tips and Recommendations
✓ Topics and content on guides are intended to focus student attention when reading/studying and
some topics may be repeated in multiple chapters.
✓ Multiple test items are derived from the same topic areas to encourage deeper comprehension.
✓ Students must have a broad understanding of content and not simply memorize passages in
textbooks or articles.
✓ Information contained in the chapters as well as boxes and table within the chapters may
include test items.
✓ Exam questions represent various levels of cognitive learning. You are expected to analyze,
synthesis, and evaluate patient scenarios in order to answer the questions.
✓ Read all of the answers BEFORE reading the stem of the question. This will help you focus on the
key content and not get distracted by extraneous information. Once you have selected your
answer, read the question one more time to ensure that the best answer has been chosen.
✓ Utilize your time well by not rushing. You will have plenty of time to read each question for
understanding before you select your final answer.
Major Content Topics:
Alterations in Immunity & Inflammation
• Hypersensitivity
• Immunodeficiency
• Autoimmunity
Alterations in Hematologic Function
• Anemia
• Role of erythropoietin in RBC production
• Primary site of RBC production
• Anemia
• Microcytic anemias
• Macrocytic anemias
• Normocytic anemias
• Hemoglobinopathies
Alterations of Cardiovascular Function
• Coronary artery disease
Definition: imbalance between myocardial oxygen demand and supply from coronary arteries
Prolonged O2 demand on the heart leads to Myocardial Infraction
Cause: Atherosclerosis of coronary arteries with myocardial ischemia
, PATHO: LDL in blood overtime starts to stick to artery wall. It grows over time which limits the blood flow
to heart. As people do activity, sob and chest pain with activities. Goes away with rest.-stable angina
Unstable: plaque rupture: artery wall messed up, body sends clotting factors to artery to repair it and
forms a thrombus.
ACS: Thrombus keeps growing and growing which stops blood flow : unstable angina (chest pain
unrelieved by rest and nitroglycerin doesn’t relieve chest pain.
Once thrombus completes blocks blood flow= MI(heart muscle dies)
Non-modifiable: age(men > 45 y/o ; women > 55 y/o), family history
modifiable:: Elevated LDL(BAD) & Decreased HLD(Good), Hypertension, Diabetes, smoking
Present as Stable Angina, Prinzmetal Angia, Acute Coronary Syndrome(unstable angina, Non ST
elevation, MI, NSTEMI, STEMI Chronic Ischemia heart disease, sudden cardiac death)
Less common cause:
Coronary Embolus: A-Fib, Infective endocarditis, left atrial or ventricular thrombus, cardiac cath
Vasculitis(CAD in Children): * Kawasaki disease (medium vessel vasculitis cause coronary artery
aneurysm)
Vasospasm: reduce blood flow
Aortic Valve Stenosis: not enough blood to coronaries leading to myocardial ischemia
Causes of concentric ventricular hypertrophy: HTN, hypertrophic cardiomyopathy d/t more heart
muscle to supply
Stable(Plaque) Angina(hasn’t ruptured)
(Near -total occlusion w/ no infraction of b/c atherosclerotic plaque grows slowly gives heart to develop
**collateral circulationRerouting**)- that supplies the hyperperfused area
Secondary to Myocardial Ischemia(Reversible Cell Injury)
Atherosclerotic plaque occluding > 75% of coronary artery lumen
S/S chest pain with activity, sob, fatigue-goes away with rest
Infraction: Irreversible cell injury or death
Described as :
Deep poorly localized squeezing, crushing, suffocating, retrosternal pain(jaw, neck, arm)
Other symptoms: sob, nausea, vomiting, diaphoresis, fatigue, dizziness
*** Reproducible during: Physical exertion or Emotional Stress***
