Test bank for rubin s pathology clinicopathologic foundations of medicine 7th edition with answer key

TEST BANK FOR RUBIN’S PATHOLOGY: CL
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Chapteru1:uCelluAdaptation,uInjuryuanduDeath

Ischemiauanduotherutoxicuinjuriesuincreaseutheuaccumulationuofuintracellularucalciumuasuauresult
u

1. of:
A) releaseuofustoreducalciumufromutheumitochondria.
B) improveduintracellularuvolumeuregulation.
C) decreaseduinfluxuacrossutheucellumembrane.
D) attractionuofucalciumutoufattyuinfiltrates.
Theupatientuisufoundutouhaveuliverudisease,uresultinguinutheuremovaluofuaulobeuofuhisuliver.
2. Adaptationutoutheureducedusizeuofutheuliveruleadsutou_ ofutheuremaininguliverucells.
A) metaplasia
B) organuatrophy
C) compensatoryuhyperplasia
D) physiologicuhypertrophy
Aupersonueatingupeanutsustartsuchokinguanducollapses.uHisuairwayuobstructionuisupartiallyucl
eared,ubutuheuremainsuhypoxicuuntiluheureachesutheuhospital.uTheuprolongeducelluhypoxia
3. causeduaucerebraluinfarctionuanduresulting _uinutheubrain.
A) caspaseuactivation
B) coagulationunecrosis
C) rapiduphagocytosis
D) proteinup53udeficiency
Bacteriauanduvirusesucauseucelludamageuby ,uwhichuisuuniqueufromutheuintracellular
4. damageucausedubyuotheruinjuriousuagents.
A) disruptingutheusodium/potassiumuATPaseupump
B) interruptinguoxidativeumetabolismuprocesses
C) replicatinguanduproducingucontinueduinjury

,TEST BANK FOR RUBIN’S PATHOLOGY: CL
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D) decreasinguproteinusynthesisuandufunction
Theupatientuhasuauprolongeduinterruptionuinuarterialublooduflowutouhisuleftukidney,ucausing
5. hypoxicucelluinjuryuandutheureleaseuofufreeuradicals.uFreeuradicalsudamageucellsuby:
A) destroyinguphospholipidsuinutheucellumembrane.
B) alteringutheuimmuneuresponseuofutheucell.
C) disruptingucalciumustorageuinutheucell.
D) inactivationuofuenzymesuandumitochondria.

,TEST BANK FOR RUBIN’S PATHOLOGY: CL
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6. Injureducellsuhaveuimpaireduflowuofusubstancesuthroughutheucellumembraneuasuauresultuof:
A) increasedufatuload.
B) alteredupermeability.
C) altereduglucoseuutilization.
D) increasedusurfaceureceptors.
7. Reversibleuadaptiveuintracellularuresponsesuareuinitiateduby:
A) stimulusuoverload.
B) geneticumutations.
C) chemicalumessengers.
D) mitochondrialuDNA.
8. Injureducellsubecomeuveryuswollenuasuauresultuof:
A) increaseducelluproteinusynthesis.
B) altereducelluvolumeuregulation.
C) passiveuentryuofupotassiumuintoutheucell.
D) blebuformationuinutheuplasmaumembrane.
Audiabeticupatientuhasuimpairedusensation,ucirculation,uanduoxygenationuofuhisufeet.uHeustepsuonuau
pieceuofuglass,utheuwoundudoesunotuheal,uandutheuareautissueubecomesunecrotic.uTheunecrotic
9. celludeathuisucharacterizeduby:
A) rapiduapoptosis.
B) cellularurupture.
C) shrinkageuanducollapse.
D) chronicuinflammation.
Au99-year-olduwomanuhasuexperiencedutheudeclineuofucellufunctionuassociateduwithuage.uA
10. groupuofutheoriesuofucellularuagingufocusuonuprogrammed:
A) changesuwithugeneticuinfluences.
B) eliminationuofucellureceptorusites.
C) insufficientutelomeraseuenzyme.

, TEST BANK FOR RUBIN’S PATHOLOGY: CL
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D) DNAumutationuorufaultyurepair.
Anu89-year-
oldufemaleupatientuhasuexperiencedusignificantudecreasesuinuherumobilityuandustaminauduringuau
3-
weekuhospitalustayuforutheutreatmentuofuaufemoraluheadufracture.uWhichuofutheufollowingupheno
menaumostulikelyuaccountsuforutheupatientsudecreaseuinumuscleufunction
11. thatuunderliesuherureducedumobility?
A) Impairedumuscleucellumetabolismuresultingufromumetaplasia
B) Dysplasiauasuauconsequenceuofuinflammationuduringuboneuremodeling
C) Disuseuatrophyuofumuscleu cellsuduringuauprolongeduperioduofuimmobility