NURS 2514 Week 2 Upper & Lower GI
Pharmacology 2025/2026 Exam
Questions and Verified Answers |
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Ondansetron - 🧠 ANSWER ✔✔Type: antiemetic
Class: Serotonin Receptor Antagonists
MOA: Acts on serotonin blocking receptors = less available serotonin In CTZ
Adverse Effects: Headache, constipation, diarrhea, dizziness Urinary retention,
muscle pain QT PROLONGATION (Most Important)
Dexamethasone - 🧠 ANSWER ✔✔Type: antiemetic
,Class: glucocorticoid
MOA: unknown
Adverse Effects: No negative effects when used for symptom management briefly
Nursing Considerations: used for nausea associated with chemotherapy. Can be
used alone or combined with other antiemetics (Ondansetron)
Metoclopramide - 🧠 ANSWER ✔✔Type: antiemetic
Class: Dopamine Antagonist
MOA: Blocks dopamine and serotonin receptors in the CTZ, enhances upper GI
tract response to acetycholine (↑ peristalsis)
Adverse Effects: in high doses, diarrhea and sedation are common
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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PRIVACY STATEMENT. ALL RIGHTS RESERVED
, with long term use: risk of tardive dyskinesia (repetitive, involuntary movements
of arms, legs, facial muscles)
Counterindication: patients with GI obstruction, perforation or hemorrhage Due to
increased peristalsis
Nursing Considerations: GI Assessment, Assess mental status (drowsiness) Look
for uncontrolled movement
Nabilone - 🧠 ANSWER ✔✔Type: antiemetic
Class: cannabinoid
MOA: activation of receptors around the vomiting center
Effect: used to suppress chemo induced nausea and vomiting
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
3
PRIVACY STATEMENT. ALL RIGHTS RESERVED
Pharmacology 2025/2026 Exam
Questions and Verified Answers |
Already Graded A+
Ondansetron - 🧠 ANSWER ✔✔Type: antiemetic
Class: Serotonin Receptor Antagonists
MOA: Acts on serotonin blocking receptors = less available serotonin In CTZ
Adverse Effects: Headache, constipation, diarrhea, dizziness Urinary retention,
muscle pain QT PROLONGATION (Most Important)
Dexamethasone - 🧠 ANSWER ✔✔Type: antiemetic
,Class: glucocorticoid
MOA: unknown
Adverse Effects: No negative effects when used for symptom management briefly
Nursing Considerations: used for nausea associated with chemotherapy. Can be
used alone or combined with other antiemetics (Ondansetron)
Metoclopramide - 🧠 ANSWER ✔✔Type: antiemetic
Class: Dopamine Antagonist
MOA: Blocks dopamine and serotonin receptors in the CTZ, enhances upper GI
tract response to acetycholine (↑ peristalsis)
Adverse Effects: in high doses, diarrhea and sedation are common
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
2
PRIVACY STATEMENT. ALL RIGHTS RESERVED
, with long term use: risk of tardive dyskinesia (repetitive, involuntary movements
of arms, legs, facial muscles)
Counterindication: patients with GI obstruction, perforation or hemorrhage Due to
increased peristalsis
Nursing Considerations: GI Assessment, Assess mental status (drowsiness) Look
for uncontrolled movement
Nabilone - 🧠 ANSWER ✔✔Type: antiemetic
Class: cannabinoid
MOA: activation of receptors around the vomiting center
Effect: used to suppress chemo induced nausea and vomiting
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
3
PRIVACY STATEMENT. ALL RIGHTS RESERVED
