NR 293
NR 293 Pharm Exam 1 Chamberlain
Risks for injury - know that anything can be a possible risk for patient injury
9 rights of medicine administration - right patient, right dose, right medication, right time,
right documentation, right route, right reason, right response
what is a prototype - the first drug of a class that all others are based from (ex- morphine)
what is pharmacokinetics - what the body does to the drug
what is pharmacodynamics - what the drug does to the body
bioavailability - what portion of the drug that entered the circulation can have an effect on
the body
first pass effect - a drug enters the GI tract and is filtered to the liver where some is
destroyed
what enzymes work in the liver - P-450 enzymes
if a patient has cirrhosis of the liver, what will happen when they take a medication? -
When the medication passes through the liver for the first pass, there will be less P-450
enzymes so the bioavailability of the medication will be higher and it will circulate in the
bloodstream longer.
half life - time required for 50% of the drug to be removed from the body
NR 293
,NR 293
Pharmacotherapeutics - treatment of conditions
enteral route - through the GI tract
parenteral tract - outside the GI tract
how is medication absorption different for neonates and children? - they have less gastric
acid to break down medications and availability is higher
why do more drugs enter neonate and children's brains, why are meds not as easily
excreted/destroyed by liver and kidneys ? - immature BBB, liver, and kidneys
Polypharmacy - The use of multiple medications on a regular basis
during which phase of the nursing process does a nurse prioritize the nursing diagnoses? -
planning
the nurse recognizes that drugs given by which route will be altered by the first pass
effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal - oral and rectal
NR 293
, NR 293
the nurse is reviewing a list of a patient's medications and notes one of the drugs has a
low therapeutic index. what does this mean? - the difference between a therapeutic dose
and a toxic dose are very close together
when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of
drug B? - level of drug B could rise to toxicity
A drug is highly protein bound, what does this mean? - it will have a longer duration of
action
do no harm is what ethical principle? - nonmaleficence
Which legal act required drug manufacturers to establish the safety and efficacy of a new
drug before its approval for use? - Kefauver-Harris, amendment of 1962
over the counter drugs (otc) are - nonprescription drugs that are used for short term
treatment
what herbal supplement is used to promote sleep and relaxation, prolonged use can cause
yellow discoloration of nails, risk for liver toxicity - kava
herbal supplement used to decrease nausea and vomiting induced by chemotherapy -
ginkgo
which drug classes are used as OTC remedies ?
a. NSAIDs
b. cold remedies
c. antibiotics
NR 293
NR 293 Pharm Exam 1 Chamberlain
Risks for injury - know that anything can be a possible risk for patient injury
9 rights of medicine administration - right patient, right dose, right medication, right time,
right documentation, right route, right reason, right response
what is a prototype - the first drug of a class that all others are based from (ex- morphine)
what is pharmacokinetics - what the body does to the drug
what is pharmacodynamics - what the drug does to the body
bioavailability - what portion of the drug that entered the circulation can have an effect on
the body
first pass effect - a drug enters the GI tract and is filtered to the liver where some is
destroyed
what enzymes work in the liver - P-450 enzymes
if a patient has cirrhosis of the liver, what will happen when they take a medication? -
When the medication passes through the liver for the first pass, there will be less P-450
enzymes so the bioavailability of the medication will be higher and it will circulate in the
bloodstream longer.
half life - time required for 50% of the drug to be removed from the body
NR 293
,NR 293
Pharmacotherapeutics - treatment of conditions
enteral route - through the GI tract
parenteral tract - outside the GI tract
how is medication absorption different for neonates and children? - they have less gastric
acid to break down medications and availability is higher
why do more drugs enter neonate and children's brains, why are meds not as easily
excreted/destroyed by liver and kidneys ? - immature BBB, liver, and kidneys
Polypharmacy - The use of multiple medications on a regular basis
during which phase of the nursing process does a nurse prioritize the nursing diagnoses? -
planning
the nurse recognizes that drugs given by which route will be altered by the first pass
effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal - oral and rectal
NR 293
, NR 293
the nurse is reviewing a list of a patient's medications and notes one of the drugs has a
low therapeutic index. what does this mean? - the difference between a therapeutic dose
and a toxic dose are very close together
when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of
drug B? - level of drug B could rise to toxicity
A drug is highly protein bound, what does this mean? - it will have a longer duration of
action
do no harm is what ethical principle? - nonmaleficence
Which legal act required drug manufacturers to establish the safety and efficacy of a new
drug before its approval for use? - Kefauver-Harris, amendment of 1962
over the counter drugs (otc) are - nonprescription drugs that are used for short term
treatment
what herbal supplement is used to promote sleep and relaxation, prolonged use can cause
yellow discoloration of nails, risk for liver toxicity - kava
herbal supplement used to decrease nausea and vomiting induced by chemotherapy -
ginkgo
which drug classes are used as OTC remedies ?
a. NSAIDs
b. cold remedies
c. antibiotics
NR 293
