The second postganglionic neuron terminates on smooth muscle, cardiac muscle, or
a gland at a specializes synapse called the __________ ________.
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Neuroeffector junction
What are Adrenergic Neurotransmitters?
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norepinephrine, epinephrine, dopamine
What drug is this?
•Alpha 1 agonist : Very little beta activity
Expected therapeutic effects
-Given IV to maintain BP
-Ophthalmic drops for mydriasis
-Intranasal and oral OTC for nasal congestion
Contraindications/cautions
-HTN, bradycardia, CAD, angina, glaucoma, hyperthyroidism, diabetes
Potential side effects or adverse reactions
-nasal burning or stinging
-rebound nasal congestion
-photophobia
-tremor, reflex bradycardia
-severe vasoconstriction
Potential interactions
-hypertensive crisis with MAOIs
-caffeine increases CNS stimulation
Nursing Considerations
-Monitor pulse, BP, central venous pressure with IV administration
-Watch IV rate and site carefully
-Observe for rebound congestion with nasal med
Patient/Family Teaching
-Ophthalmic drops may cause stinging or burning
-Talk to doctor if no relief within 5 days
-Wear sunglasses after using eye drops
, -Don't share nasal sprays
-Don't take more than recommended dose
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Phenylephrine
Norepinephrine -- Epinephrine -- Dopamine Actions
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•Has an intense short reaction
•Reabsorbed or metabolized by monoamine oxidase (MAO) or catechol-
O-methyltransferase (COMT)
Fill in the blanks to describe the mechanism of action of prazosin
Prazosin competes with ______ at alpha-adrenergic _________ on vascular _______ muscle in
arterioles veins. It works selectively on alpha __________ receptors.
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NE
Answer 1 : norepinephrine
Answer 2: receptors
Answer 3: smooth
Answer 4: 1
Stimulation of adrenergic receptors can be what three things?
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a gland at a specializes synapse called the __________ ________.
Give this one a try later!
Neuroeffector junction
What are Adrenergic Neurotransmitters?
,Give this one a try later!
norepinephrine, epinephrine, dopamine
What drug is this?
•Alpha 1 agonist : Very little beta activity
Expected therapeutic effects
-Given IV to maintain BP
-Ophthalmic drops for mydriasis
-Intranasal and oral OTC for nasal congestion
Contraindications/cautions
-HTN, bradycardia, CAD, angina, glaucoma, hyperthyroidism, diabetes
Potential side effects or adverse reactions
-nasal burning or stinging
-rebound nasal congestion
-photophobia
-tremor, reflex bradycardia
-severe vasoconstriction
Potential interactions
-hypertensive crisis with MAOIs
-caffeine increases CNS stimulation
Nursing Considerations
-Monitor pulse, BP, central venous pressure with IV administration
-Watch IV rate and site carefully
-Observe for rebound congestion with nasal med
Patient/Family Teaching
-Ophthalmic drops may cause stinging or burning
-Talk to doctor if no relief within 5 days
-Wear sunglasses after using eye drops
, -Don't share nasal sprays
-Don't take more than recommended dose
Give this one a try later!
Phenylephrine
Norepinephrine -- Epinephrine -- Dopamine Actions
Give this one a try later!
•Has an intense short reaction
•Reabsorbed or metabolized by monoamine oxidase (MAO) or catechol-
O-methyltransferase (COMT)
Fill in the blanks to describe the mechanism of action of prazosin
Prazosin competes with ______ at alpha-adrenergic _________ on vascular _______ muscle in
arterioles veins. It works selectively on alpha __________ receptors.
Give this one a try later!
NE
Answer 1 : norepinephrine
Answer 2: receptors
Answer 3: smooth
Answer 4: 1
Stimulation of adrenergic receptors can be what three things?
Give this one a try later!
