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APEA MyQ Bank - Principles of
Pharmacology QUESTIONS AND
CORRECT DETAILED ANSWERS
Pharmacokinetics is:
A. The effect the drug has on the body.
B. The adverse response of the drug on the body.
C. The effect the body has on the drug.
D. The clinical formulation of the drug
Ans: C. The effect the body has on the drug.
Absorption, distribution, metabolism, excretion
The ratio of minimum effective concentration (MEC) to minimum toxic
concentration (MTC) of a drug is the:
Ans: therapeutic window
half life:
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Ans: the time it takes for the plasma concentration of the drug
to be reduced to half of its original value
Drug clearance formula
Ans: rate of drug elimination / plasma concentration of the
drug
steady state
Ans: when the rate of drug input equals the rate of drug
elimination
Which of the following actions triggers a rise in membrane or action
potential of a cell?
A. Opening of the voltage gated sodium ions
B. Closure of voltage gated sodium ions
C. Opening of calcium ion channel
D. Opening of potassium voltage gated channels
Ans: A. Opening of the voltage gated sodium ions
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Before stimulation, a cell has a slightly negative electric charge
(compared with ECF). Outside is more positively charged. When
stimulus is encountered, sodium ion channel opens and sodium
rushes into the cell, causing depolarization (rise in
membrane/action potential)
The process by which a drug's activity is altered in order to prepare it
for excretion:
Ans: biotransformation
The amino acid found in dairy products, fish, and eggs is tyrosine. The
amino acid from which tyrosine is made is:
Ans: phenylalanine.
People take tyrosine to help manage depression, ADD, ADHD,
narcolepsy, and to improve alertness following sleep
deprivation
The correct order of the transmission of a neurotransmitter is
presynaptic preparation followed by:
Ans: arrival of action potential, release of transmitter, receptor
interaction, and the termination of transmitter action
All rights reserved © 2025/ 2026 |
APEA MyQ Bank - Principles of
Pharmacology QUESTIONS AND
CORRECT DETAILED ANSWERS
Pharmacokinetics is:
A. The effect the drug has on the body.
B. The adverse response of the drug on the body.
C. The effect the body has on the drug.
D. The clinical formulation of the drug
Ans: C. The effect the body has on the drug.
Absorption, distribution, metabolism, excretion
The ratio of minimum effective concentration (MEC) to minimum toxic
concentration (MTC) of a drug is the:
Ans: therapeutic window
half life:
All rights reserved © 2025/ 2026 |
, Page |2
Ans: the time it takes for the plasma concentration of the drug
to be reduced to half of its original value
Drug clearance formula
Ans: rate of drug elimination / plasma concentration of the
drug
steady state
Ans: when the rate of drug input equals the rate of drug
elimination
Which of the following actions triggers a rise in membrane or action
potential of a cell?
A. Opening of the voltage gated sodium ions
B. Closure of voltage gated sodium ions
C. Opening of calcium ion channel
D. Opening of potassium voltage gated channels
Ans: A. Opening of the voltage gated sodium ions
All rights reserved © 2025/ 2026 |
, Page |3
Before stimulation, a cell has a slightly negative electric charge
(compared with ECF). Outside is more positively charged. When
stimulus is encountered, sodium ion channel opens and sodium
rushes into the cell, causing depolarization (rise in
membrane/action potential)
The process by which a drug's activity is altered in order to prepare it
for excretion:
Ans: biotransformation
The amino acid found in dairy products, fish, and eggs is tyrosine. The
amino acid from which tyrosine is made is:
Ans: phenylalanine.
People take tyrosine to help manage depression, ADD, ADHD,
narcolepsy, and to improve alertness following sleep
deprivation
The correct order of the transmission of a neurotransmitter is
presynaptic preparation followed by:
Ans: arrival of action potential, release of transmitter, receptor
interaction, and the termination of transmitter action
All rights reserved © 2025/ 2026 |
