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Exam (elaborations)

ACS EXAM QUESTIONS WITH COMPLETE SOLUTIONS

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ACS EXAM QUESTIONS WITH COMPLETE SOLUTIONS

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ACS
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ACS








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ACS
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ACS

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July 17, 2025
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2024/2025
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ACS4

In a helix, the R groups on the amino acid residues: - ANSWERSThe R groups of the amino acids
stick outward from the α helix



pI - ANSWERSpH value where the net charge of an ionizable species is zero



Peptide Bonds (resonance) - ANSWERSpolarity of the peptide bond increases; has partial double
bond character; carbonyl carbon and amide N are coplanar- free rotation about the bond is
resctricted



Ramachandran plot - ANSWERSdisplays allowed regions of protein folding space. Phi-psi angle
combinations are shown. Green areas indicate which combinations are most favorable



role of b-marcaptoethanol in reducing disulfide bonds - ANSWERSused to fully break the
covalent disulfide bond. Used in Anfinsen's experiment



nucleotides - ANSWERSmonomer unit for nucleic acids and are compoposed of nitrogenous
base, 5-carbon sugar, and a phosphate group



DNA - ANSWERSmore stable; carrier of genetic information, double stranded



RNA - ANSWERSless stable; intermediate expression of genetic information. Can form secondary
structure by H-bonding with itself.



tRNA - ANSWERStransfer RNA, holds amino acids used in protein synthesis, wobble position

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