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GRADE 9 NOTES AQA Biology GCSE Topic 5 Homeostasis

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These are in-depth notes for topic 5 homeostasis in the AQA Biology GCSE. It covers everything you need to know for your GCSE exam for topic 5, highlighting the important parts of the specification to help you get those top GRADE 9s.

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Topic 5: Homeostasis Synapse Pathway (words)
Required Practical 7  Nerve impulses arrive at synapse
Required Practical 8  Neurotransmitter (chemical messenger) is
released into the synapse
Homeostasis:  Neurotransmitter diffuses across the synapse
 Maintenance of a constant internal  Neurotransmitter binds with the receptor of
environment the membrane of the post-synaptic neuron
 Keep out body at optimum conditions despite  Binding of neurotransmitters to receptor
internal & external conditions for enzyme stimulates impulse in the post-synaptic neuron
control & cell functions
Factors affecting reaction time
Features of a nerve cell/neuron  Age
 Dendrites to contact other nerves at synapses  Drugs
using neurotransmitters  Alcohol
 Long axon to transport electrical impulses to  Neurological Disease
other nerve cells  Tiredness
 Large surface area  Caffeine
 Myelin sheath to insulate nerve impulses  Stimulus
 Mitochondria provides energy to make  Distractions
neurotransmitters
The Brain
The nervous system  Made up of neurons
 2 parts:  Part of the CNS w/ spinal cord
o Peripheral nervous system  Cerebral cortex – consciousness, intelligence,
o Central nervous system – Brain & Spinal memory & language – top & front
Chord  Cerebellum – controls muscle movement –
 A response starts with a stimulus and a bottom & back
receptor  Medulla – control unconscious actions e.g.
 Stimulus: Detectable change in the breathing, digestions, heartbeat, in the
environment bottom stem
 Pituitary Gland – hormones, little sticking out
Types of Neurons: at front of brain
 3 types:  Hypothalamus – temperature control, top of
o Sensory neuron: pituitary gland tube
 E.g. the auditory or optic nerve  Difficult to examine/study/treat brain:
o Interneuron (relay neuron): o Complex
 Co-ordinates o Delicate/easily damaged
o Motor neuron: o Drugs can’t reach brain because of
 Moving membrane around it
o Don’t know what part of the brain does
Reflexes VS Reactions: what
 Reflexes are automatic responses to a  Map out the brain by:
stimulus that protect us from harm. They are o Study patients with brain damage –
very fast and we don’t think about them. E.g. damage to a certain area of brain
fight or flight corresponds to damage elsewhere so
 Reactions are thinking responses. you know what that part of the brain
does
Nervous Pathway: o Electrically stimulating parts of the brain
Stimulus  Receptor  Sensory Neuron  (synapse) – pushing an electrode into the brain.
 Interneuron  (synapse) Motor Neuron  Stimulation will cause a mental/physical
Effector  Response change – to get info on the role of this
part
Synapses Pathway
o MRI Scanning – magnetic resonance
Electrical impulse  Release of neurotransmitters 
imaging scanner creates a map of the
Diffuse into the other neuron  fits into the other
brain to show which part of the brain is
receptor (Specific & complimentary)  electrical
active/affected by a tumour
impulse continues to post synaptic neuron

, o EEG Electroencephalogram – visual o Long-sightedness
record of electronic activity by neurons – o Focal point is too far
amplifies & detects electrical signals o Lens is too thin/eyeball is too
from the brain short/cornea is less curved
o Convex lenses - Move the focal point
The Eye forwards
 Sensitive to light o Corrects hyperopia
 Retina – layer of light sensitive cells found at  Treatment:
the back of the eye o Generally these defects are treated with
 Fovea – focal point – light should hit here spectacle lenses which refract the light
 Optic nerve – sends signals to the brain from rays so that they do focus on the retina
eye o New technologies now include hard and
 Sclera – Strong white outer layer that soft contact lenses, laser surgery to
supports the structure of the eye & prevents change the shape of the cornea and a
damage replacement lens in the eye.
 Cornea – Curved transparent at the front of Endocrine System:
the eye to refract light  Pituitary Gland – master gland that secretes
 Iris – Muscles that control the size of the pupil hormones
 Ciliary muscles & Suspensory ligaments – hold  Pancreas – secretes insulin and glucagon to
the lens in place & controls its shape control blood glucose
(antagonistic muscles – muscles with opposite  Thyroid – secretes thyroxine to control
effect) metabolic, heart rate & temperature 
 Pupil Reflex: (Thyroxine from the thyroid gland stimulates
o Too much light the basal metabolic rate. It plays an important
 Damage to light sensitive cells role in growth and development)
 Circular muscles contract  Adrenal Gland – secretes adrenaline for fight
 Radial muscles relax or flight  (Adrenaline is produced by the
 Pupil constrict adrenal glands in times of fear or stress. It
o Too less light increases the heart rate and boosts the
 Not enough stimulus to cells delivery of oxygen and glucose to the brain
 Circular muscles relax and muscles, preparing the body for ‘flight or
 Radial muscles contract fight’)
 Pupil dilate  Oestrogen – secretes oestrogen for the
 Accommodation – The process of the eye menstrual cycle & for secondary sex
changing shape to focus on a near of distant characteristics
object  Testes – secretes testosterone for the sperm
o Near Object & for secondary sex characteristics
 Ciliary muscles contract  Works slower than nervous system but acts
 Suspensory ligaments loosen longer
 Lens is thicker + more curved =  Blood transports hormone to target
refract light rays strongly organ/tissue
o Far Object  Endocrine – secrets chemicals inside body
 Ciliary muscles loosen  Exocrine – secretes chemicals outside body
 Suspensory ligaments tighten Control of Body Temperature:
 Lens is thinner = refract light rays  37°C – optimum temperature
weakly  Too hot – enzymes denature
 Myopia:  Too cold – enzymes work too slowly
o Short-sightedness  Monitored & controlled by the
o Focal point is too short thermoregulatory centre in the brain
o Lens is too curved/eyeball is  Blood goes through the thermoregulatory
too wide/cornea is too centre in the brain (hypothalamus) and it
curved monitors the body temp by sensing the blood
o Concave lenses - Moves the temp
focal point backwards  External surface temperature is monitored by
o Corrects myopia receptors in the skin that send impulses to the
thermoregulatory centre
 Hyperopia:
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