Georgette Review PMHNP LATEST UPDATE 2025-2026
\COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS
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When many answers are wrong
remarkably similar, they are
usually _____________
Interprofessional Collaborate is
collaboration is usually right.
encouraged. Delegate is
usually wrong.
ADPIER Assessment, diagnosis, Plan, intervention, evaluate, refer out last.
Lithium Normal 0.6-1.2
Lithium toxicity occurs at levels > 1.5
severe nausea, diarrhea, vomiting, confusion, drowsiness,
Signs of Lithium toxicity
muscle weakness, heart palpitation, coarse hand
tremors, unsteady gait
Lithium is gold standard for MANIA
Lithium has evidence shown to reduce suicidal ideation
What does lithium cause in Ebstein anomaly (congenital heart defect)
neonate, especially 1st
trimester
dehydration and rise
hyponatremia cause lithium
levels to
TSH
creatinine (0.6-1.2)
BUN (10-20)
Baseline labs before initiation
HCG (all psychotropics
of lithium
females 12-51) EKG 50+
Urinalysis (check for proteins, 4+ may indicate kidney disease)
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hypothyroidism
coase hand tremors with
toxicity maculopapular
Side Effects of Lithium rash
diarrhea, vomiting, cramps--signs of
toxicity. Monitor closely. anorexia
t wave
inversions
leukocyto
sis
staying
Pt education for lithimum hydrated
avoiding
NSAIDS
complianc
e
Depakote normal level 50-125
Depakote toxicity level greater than 150
Teratogenic effects of spina bifida
Depakote
alopecia
Adverse effects of depakote hepatotoxicity (RUQ pain or brown/red urine--order
LFTs) AST 5-40, ALT 5-35, yellowing of skin or eyes,
fatigue
Signs of Depakote toxicity disorientation, lethargy, respiratory depression, nausea/vomiting
DC med
check
Intervention for depakote toxicity
level LFT
ammonia
MAOI + tyramine causes hypertensive crisis
elevated BP
sudden explosive like
headache facial
Symptoms of hypertensive flushing
crisis palpitations
pupillary dilation
diaphoresis
fever
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MEPERI
DINE
STIMULA
NTS
Hypertensive crisis occurs
with MAOI + decongesta
nts TCAs
atypicals
St. John's
wart L-
tryptoph
an
asthma
meds
DC offending
Treatment for hypertensive
crisis agent Administer
PHENTOLAMINE
Teratogenic effects of benzos floppy baby, cleft palate
Teratogenic effects of tegratol neural tube defect
teratogenic effects of lithium ebstein anomaly (heart defect) (avoid, especially 1st trimester)
teratogenic effects of neural tube defects/spina bifida
depakote
Adverse reaction to Lamictal Steven Johnson's Syndrome
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FEVER --high
yield sore
throat
facial
swelling
Signs of SJS tongue
swelling
red rash
skin
sloughing
body
aches
prodromal
headache
malaise
arthralgia
painful mucus membranes
Lamotrigine is least likely to sedation or weight gain
cause
agranulocytosis (decrease WBCs)
Carbamazepine (tegretol)
aplastic anemia (pallor, fatigue, HA, fever, nosebleeds,
black box warning
bleeding gums, skin rash, SOA)
Screen for HLAB-1502 allele before initiating, due to
Carbamazepine and asians
high incidence of SJS if positive for allele.
check for pregnancy before starting mood stabilizer
Child-bearing aged women start on folic acid to support neural tube development
during the first month that a woman is pregnant
Clozaril/clozapine can cause agranulocytosis and neutropenia
For monitoring neutropenia ANC
in Clozaril, monitor
DC clozarli if ANC less than 1000
DC clozaril if WBC 2000-3000, risk of agranulocytosis
When on clozaril monitor for signs and symptoms of infection: sudden fever, chills, sore throat,
weakness
Clozaril only known decrease risk of suicide in patients with schizophrenia.
antipsychotic to
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